1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE
- CAS No.
- 6001-64-5
- Chemical Name:
- 1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE
- Synonyms
- MET;CHLOROBUTANOL HEMIHYDRATE;CHLORETONE;CHLOROBUTANOL HYDROUS;CHLORBUTE;CHLORBUTOL;MET HEMIHYDRATE;ACETONE CHLOROFORM;Chlorobutanol Base;ACETONE CHLOROFORME
- CBNumber:
- CB2134363
- Molecular Formula:
- C8H16Cl6O3
- Molecular Weight:
- 372.93
- MDL Number:
- MFCD02179352
- MOL File:
- 6001-64-5.mol
- MSDS File:
- SDS
Melting point | 77-79 °C(lit.) |
---|---|
Boiling point | 173-175 °C |
Flash point | 100 °C |
storage temp. | 2-8°C |
solubility | Slightly soluble in water, very soluble in ethanol (96 per cent), soluble in glycerol (85 per cent). |
form | Crystalline Powder, Crystals and/or Chunks |
color | White to almost white |
Water Solubility | Soluble in ethanol, ether, chloroform, and glycerol. Insoluble in water. |
Merck | 14,2129 |
BRN | 878167 |
Stability | Stable. Generates toxic fumes on combustion. Incompatible with strong oxidizing agents. |
LogP | 2.074 (est) |
CAS DataBase Reference | 6001-64-5 |
FDA UNII | 3X4P6271OX |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H302 | |||||||||
Precautionary statements | P301+P312+P330 | |||||||||
Hazard Codes | Xn | |||||||||
Risk Statements | 22-36/37/38 | |||||||||
Safety Statements | 26-36/37/39 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | UC0175000 | |||||||||
TSCA | Yes | |||||||||
HS Code | 29055900 | |||||||||
NFPA 704 |
|
1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE price More Price(34)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | SAB1305534 | MONOCLONAL ANTI-BI-PHOSPHO-MET/HGFR(Y1234/Y1235) antibody produced in mouse clone 6AT1877, IgG fraction of antiserum, buffered aqueous solution | 6001-64-5 | 400μl | $481 | 2024-03-01 | Buy |
Sigma-Aldrich | 112054 | 1,1,1-Trichloro-2-methyl-2-propanol hemihydrate 98% | 6001-64-5 | 50g | $57 | 2024-03-01 | Buy |
Sigma-Aldrich | 1112503 | Chlorobutanol United States Pharmacopeia (USP) Reference Standard | 6001-64-5 | 200mg | $491 | 2024-03-01 | Buy |
Sigma-Aldrich | Y0002029 | Chlorobutanol hemihydrate European Pharmacopoeia (EP) Reference Standard | 6001-64-5 | Y0002029 | $150 | 2023-01-07 | Buy |
Sigma-Aldrich | 1.01005 | 1,1,1-Trichloro-2-methyl-2-propanol hemihydrate EMPROVE? ESSENTIAL, Ph. Eur., BP, JP, NF | 6001-64-5 | 1KG | $221 | 2022-05-15 | Buy |
1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE Chemical Properties,Uses,Production
Chemical Properties
white crystalline solid
Uses
1,1,1-Trichloro-2-methyl-2-propanol hemihydrate in combination with dimethyl sulfone, can serve as an appropriate solvent for the freeze drying of certain parenteral organic drugs, which have an increase in many factors such as stability, dissolution rate, dosing accuracy and sterility.
Uses
Pharmaceutic aid (antimicrobial agent).
Uses
1,1,1-Trichloro-2-methyl-2-propanol hemihydrate converts benzisoxazole to α-aryloxyisobutyric acid. It forms eutectic with dimethyl sulfone, which is the most suitable media for freeze-drying due to its high solubilizing ability and a good rate of solvent removal.
brand name
Chloretone (Parke-Davis).
General Description
1,1,1-Trichloro-2-methyl-2-propanol hemihydrate (chlorobutanol) converts benzisoxazole to α-aryloxyisobutyric acid. 1,1,1-Trichloro-2-methyl-2-propanol hemihydrate (chlorobutanol) forms eutectic with dimethyl sulfone, which is the most suitable media for freeze-drying due to its high solubilizing ability and a good rate of solvent removal.
Biochem/physiol Actions
Chlorobutanol or 1,1,1-Trichloro-2-methyl-2-propanol is a opthalmic preservative and sedative hypnotic that possess antibacterial and antifungal properties. It also decreases the conduction velocity and induces conduction failure and automaticity within isolated ventricular muscle strips as well as impacts myocardial cells by acting on cell membrane and reduces isometric tension produced by heart.
1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Jiangxi Alpha Hi-tech Pharmaceutical Co., Ltd | 510-85010237 | overseamarketing@alphahi-tech.com | CHINA | 41 | 58 |
Hebei Weibang Biotechnology Co., Ltd | +8615531157085 | abby@weibangbio.com | China | 8806 | 58 |
Hebei Mujin Biotechnology Co.,Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12832 | 58 |
Wuhan Fortuna Chemical Co., Ltd | +86-027-59207850 | info@fortunachem.com | China | 5973 | 58 |
Hebei Weibang Biotechnology Co., Ltd | +8617732866630 | bess@weibangbio.com | China | 18148 | 58 |
Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29793 | 60 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
Hangzhou FandaChem Co.,Ltd. | +8615858145714 | FandaChem@Gmail.com | China | 8778 | 55 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29880 | 58 |
SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 | sales@sdzschem.com | China | 2930 | 58 |
View Lastest Price from 1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2025-01-10 | Chlorobutanol
6001-64-5
|
US $0.00 / KG | 1KG | 98.0%~101.0% | 5000kg/month | WUHAN FORTUNA CHEMICAL CO., LTD | ||
2024-12-11 | 1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE
6001-64-5
|
US $10.00 / KG | 1KG | 99% | 10 mt | Hebei Weibang Biotechnology Co., Ltd | ||
2024-11-18 | Chlorobutanol hemihydrate
6001-64-5
|
US $98.00 / g | 10g | TargetMol Chemicals Inc. |
- Chlorobutanol
6001-64-5
- US $0.00 / KG
- 98.0%~101.0%
- WUHAN FORTUNA CHEMICAL CO., LTD
- 1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE
6001-64-5
- US $10.00 / KG
- 99%
- Hebei Weibang Biotechnology Co., Ltd
- Chlorobutanol hemihydrate
6001-64-5
- US $98.00 / g
- TargetMol Chemicals Inc.
1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE Spectrum
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