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BIS(2,2,2-TRICHLORO-1,1-DIMETHYLETHYL) PHOSPHOROCHLORIDATE

BIS(2,2,2-TRICHLORO-1,1-DIMETHYLETHYL) PHOSPHOROCHLORIDATE structure

CAS No.: 17677-92-8

Chemical Name:: BIS(2,2,2-TRICHLORO-1,1-DIMETHYLETHYL) PHOSPHOROCHLORIDATE

Synonyms: BIS(2,2,2-TRICHLORO-1,1-DIMETHYLETHYL) PHOSPHOROCHLORIDATE

CBNumber:: CB7511978

Molecular Formula:: C8H12Cl7O3P

Molecular Weight:: 435.323841

MDL Number:

MOL File:: 17677-92-8.mol

Last updated:2024-12-19 13:56:28

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BIS(2,2,2-TRICHLORO-1,1-DIMETHYLETHYL) PHOSPHOROCHLORIDATE Properties

Melting point	mp 81-82 °C
solubility	crystallized from pentane
form	colorless solid

BIS(2,2,2-TRICHLORO-1,1-DIMETHYLETHYL) PHOSPHOROCHLORIDATE price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
American Custom Chemicals Corporation	HCH0136546	BIS(2,2,2-TRICHLORO-1,1-DIMETHYLETHYL) PHOSPHOROCHLORIDATE 95.00%	17677-92-8	5MG	$504.26	2021-12-16	Buy

Product number	Packaging	Price	Buy
HCH0136546	5MG	$504.26	Buy

BIS(2,2,2-TRICHLORO-1,1-DIMETHYLETHYL) PHOSPHOROCHLORIDATE Chemical Properties,Uses,Production

Uses

BIS(2,2,2-TRICHLORO-1,1-DIMETHYLETHYL) PHOSPHOROCHLORIDATE is used as a phosphorylating reagent.

Synthesis

Bis(2,2,2-trichloro-1,1-dimethylethyl) Phosphorochloridate is conveniently prepared by the reaction of 2-trichloromethyl-2-propanol with PCl3 in pyridine solvent to afford bis(2,2,2-trichloro-1,1-dimethylethyl) chlorophosphite (71%). The chlorophosphite is oxidized with (Diacetoxyiodo)benzene to give 65% of the desired phosphorochloridate (eq 1). This overall procedure represents an improved synthesis of the phosphorochloridate when compared to the different methods reported in the literature, which give mixtures of bis(2,2,2-trichloro-1,1-dimethylethyl) chlorophosphite and 2,2,2-trichloro-1,1-dimethylethyl dichlorophosphite.^[1][2]

Synthesis Reference(s)

[1](a) Gerrard, W. JCS 1944, 85. (b) Gerrard, W.; Wyvill, P. L. Research (London) 1949, 2, 536. (c) Gerrard, W.; Isaacs, M. J. D.; Machell, G.; Smith, K. B.; Wyvill, P. L. JCS 1953, 1920. (d) Gerrard, W.; Green, W. J.; Phillips, R. J. JCS 1954, 1148.
[2] (a) Abramov, V. S.; Khairullin, V. K. JGU 1957, 27, 501. (b) Sasse, K. MOC 1964, XII/2, 45.

BIS(2,2,2-TRICHLORO-1,1-DIMETHYLETHYL) PHOSPHOROCHLORIDATE Preparation Products And Raw materials

Raw materials

Preparation Products

17677-92-8(BIS(2,2,2-TRICHLORO-1,1-DIMETHYLETHYL) PHOSPHOROCHLORIDATE)Related Search:

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BIS(2,2,2-TRICHLORO-1,1-DIMETHYLETHYL) PHOSPHOROCHLORIDATE 17677-92-8