ANQ 11125
- CAS No.
- 153966-48-4
- Chemical Name:
- ANQ 11125
- Synonyms
- ANQ 11125;1-14-Motilin (swine), 3-L-phenylalanine-13-L-leucine- (9CI)
- CBNumber:
- CB21382620
- Molecular Formula:
- C86H125N19O21
- Molecular Weight:
- 1761.03
- MDL Number:
- MFCD27991292
- MOL File:
- 153966-48-4.mol
ANQ 11125 price More Price(2)
ANQ 11125 Chemical Properties,Uses,Production
Biological Activity
anq 11125 is a selective antagonist of motilin receptor with pkd of 8.24 [1].motilin receptor is a g protein-coupled receptor for motilin and stimulates contraction of gut smooth muscle.anq 11125 is a selective motilin receptor antagonist. the affinity of anq 11125 for motilin receptor is about 10 times less than motilin [1]. in rabbit antral smooth muscle tissue, anq-11125 bound to motilin receptor with pkd value of 8.16. while, anq-11125 didn’t induce contractions of rabbit duodenum. anq-11125 (10-5 m) induced contractile response by 29% compared to ach [2].
References
[1]. depoortere i, macielag mj, galdes a, et al. antagonistic properties of [phe3,leu13]porcine motilin. eur j pharmacol, 1995, 286(3): 241-247.
[2]. peeters tl, depoortere i, macielag mj, et al. the motilin antagonist anq-11125 blocks motilide-induced contractions in vitro in the rabbit. biochem biophys res commun, 1994, 198(2): 411-416.
ANQ 11125 Preparation Products And Raw materials
Raw materials
Preparation Products
ANQ 11125 Suppliers
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Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10259 | 58 |
Zhejiang Hangyu API Co., Ltd | +8617531972939 | anna@api-made.com | China | 2944 | 58 |
Hangzhou Peptidego Biotech Co.,Ltd. | 0571-87213919 | eric@peptidego.com | China | 6525 | 58 |
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Hangzhou Baige Pharmaceutical Technology Co. , Ltd. | 0571-85350119 15888826472 | 15888826472@163.com | China | 2729 | 58 |
Shanghai HongTide Biotechnology Co.,Ltd. | 19961912513 | sales@hongtide.com | China | 4616 | 58 |
Combio (Suzhou) Ltd. | 0512-51886999 17706251929 | office@combiosz.com | China | 2224 | 58 |