FMOC-S-trityl-L-cysteine
- CAS No.
- 103213-32-7
- Chemical Name:
- FMOC-S-trityl-L-cysteine
- Synonyms
- FMOC-CYS(TRT)-OH;FMOC-CYS(TRT);FMOC-L-CYS(TRT)-OH;Fomc-Cys(Trt)-OH;N-FMOC-S-TRITYL-L-CYSTEINE;Fmoc-Cyc(Trt)-OH;FMOC-L-CYS(TRT);Fmoc-Cys(Trt)-0H;FMOC-L-CYS(TRITYL);FMOC Cysteine (trt)
- CBNumber:
- CB2138770
- Molecular Formula:
- C37H31NO4S
- Molecular Weight:
- 585.71
- MDL Number:
- MFCD00038538
- MOL File:
- 103213-32-7.mol
- MSDS File:
- SDS
Melting point | 170-173 °C(lit.) |
---|---|
Boiling point | 763.4±60.0 °C(Predicted) |
alpha | 16 º (c=1, THF) |
Density | 1.270±0.06 g/cm3(Predicted) |
refractive index | 18 ° (C=1, THF) |
storage temp. | 2-8°C |
solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
pka | 3.70±0.10(Predicted) |
form | Powder |
color | White to almost white |
optical activity | [α]20/D +16.0±2°, c = 1% in THF |
Water Solubility | Insoluble in water. Soluble in most organic solvents. |
BRN | 4221286 |
InChIKey | KLBPUVPNPAJWHZ-UMSFTDKQSA-N |
CAS DataBase Reference | 103213-32-7(CAS DataBase Reference) |
UNSPSC Code | 12352209 |
NACRES | NA.26 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P261-P305+P351+P338 | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 36/37/38 | |||||||||
Safety Statements | 22-24/25-26 | |||||||||
WGK Germany | 3 | |||||||||
F | 9-21 | |||||||||
Hazard Note | Irritant | |||||||||
HS Code | 29309090 | |||||||||
NFPA 704 |
|
FMOC-S-trityl-L-cysteine price More Price(64)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 8.52008 | Fmoc-Cys(Trt)-OH Novabiochem? | 103213-32-7 | 25g | $72.8 | 2024-03-01 | Buy |
Sigma-Aldrich | 8.52008 | Fmoc-Cys(Trt)-OH Novabiochem? | 103213-32-7 | 100g | $183 | 2024-03-01 | Buy |
Sigma-Aldrich | 8.52008 | Fmoc-Cys(Trt)-OH Novabiochem? | 103213-32-7 | 250g | $365 | 2024-03-01 | Buy |
Sigma-Aldrich | 8.52008 | Fmoc-Cys(Trt)-OH Novabiochem? | 103213-32-7 | 1kg | $1370 | 2024-03-01 | Buy |
Sigma-Aldrich | 47695 | Fmoc-Cys(Trt)-OH ≥95.0% (sum of enantiomers, HPLC) | 103213-32-7 | 100g | $75.2 | 2024-03-01 | Buy |
FMOC-S-trityl-L-cysteine Chemical Properties,Uses,Production
Chemical Properties
white to light yellow crystal powde
Uses
Fmoc-Cys(Trt)-OH is an N-terminal protected cysteine derivative used in peptide synthesis. Some of the examples are:
- Synthesis of mono- and bi-functionalized platinum(IV) complexes to target angiogenic tumor vasculature.
- Synthesis of proteins through native chemical ligation of peptide hydrazides as thioester surrogates via solid-phase synthesis.
- Synthesis of glycoconjugates by conjugating reducing sugars to cysteine residues of peptides.
Uses
It is potentially useful for proteomics studies, and solid phase peptide synthesis techniques. Cysteine is versatile amino acid involved with many biological processes, including the formation of disulfide bonds - a critical component of protein structure. This compound could be useful as an unusual amino acid analog to aid in the deconvolution of protein structure and function.
General Description
The standard derivative for Fmoc SPPS of peptides containing Cys [1]. The Trt group is removed with 95% TFA containing 1-5% TIS. Ideally, this derivative should be introduced using the symmetrical anhydride or DIPCDI/HOBt activation [2,3] to minimize enantiomerization. If activation with uronium or phosphonium reagents, such as HBTU or PyBOP?, is to be employed, it is strongly recommended that collidine is used as the base [4], as this has been shown to significantly reduce loss of optical integrity during coupling.
The product number for this product was previously 04-12-1018.
To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
FMOC-S-trityl-L-cysteine Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Chengdu ZY Biochemical Technology Co., Ltd. | +86-86-2888626688 +8618980008884 | xuehaiying@zybiochem.com | China | 120 | 58 |
Chengdu Baishixing Science and Technology Industry Co.,Ltd | +86-15008457246 +86-15008457246 | yuki@cd-bsx.com | China | 53 | 58 |
Sichuan HongRi Pharma-Tech Co.,Ltd | +86-028-64841719 +8617390183901 | daisy@enlaibio.com | China | 1106 | 58 |
hebei hongtan Biotechnology Co., Ltd | +852-6619 3215 +86-17731935328 | sales03@chemcn.cn | China | 970 | 58 |
Hebei Zhuanglai Chemical Trading Co Ltd | +86-16264648883 +86-16264648883 | niki@zlchemi.com | China | 7245 | 58 |
Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29730 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-+86-371-66670886 | info@dakenam.com | China | 19805 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21628 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29858 | 58 |
View Lastest Price from FMOC-S-trityl-L-cysteine manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
![]() |
2025-04-26 | FMOC-S-trityl-L-cysteine
103213-32-7
|
US $0.00 / kg | 1kg | 99% | 200mt/year | Jinan Finer Chemical Co., Ltd | |
![]() |
2025-04-25 | Fmoc-L-Cys(trt)-OH
103213-32-7
|
US $50.00 / kg | 1kg | 99 | 5000 | Hebei Zhuanglai Chemical Trading Co Ltd | |
![]() |
2025-04-25 | Fmoc-Cys(Trt)-OH
103213-32-7
|
US $0.00 / Kg/Drum | 1KG | 98%min | 500kgs | WUHAN FORTUNA CHEMICAL CO., LTD |
-
- FMOC-S-trityl-L-cysteine
103213-32-7
- US $0.00 / kg
- 99%
- Jinan Finer Chemical Co., Ltd
-
- Fmoc-L-Cys(trt)-OH
103213-32-7
- US $50.00 / kg
- 99
- Hebei Zhuanglai Chemical Trading Co Ltd
-
- Fmoc-Cys(Trt)-OH
103213-32-7
- US $0.00 / Kg/Drum
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD