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7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one

7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one structure

CAS No.: 199327-61-2

Chemical Name:: 7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one

Synonyms: Gefitinib-8;quinazolin-4(3H);Gefitinib iMpurity F;Gefitinib Impurity 14;Gefitinib Impurity 17;Gefintinib Impurity 5;Getitinib interMediate;Gefitinib impurities135;Gefitinib impurities132;InterMediate of Gefitinib

CBNumber:: CB21477111

Molecular Formula:: C16H21N3O4

Molecular Weight:: 319.36

MDL Number:: MFCD12760130

MOL File:: 199327-61-2.mol

MSDS File:: SDS

Last updated:2024-07-12 17:58:41

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7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one Properties

Melting point	233-236 °C
Boiling point	519.5±60.0 °C(Predicted)
Density	1.32±0.1 g/cm3(Predicted)
storage temp.	2-8°C
solubility	DMSO (Slightly), Methanol (Slightly)
form	Solid
pka	7.10±0.10(Predicted)
color	White to Off-White
CAS DataBase Reference	199327-61-2(CAS DataBase Reference)
FDA UNII	R9YH59H93M

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H319-H335-H302+H312+H332-H315
Precautionary statements	P260-P273-P280-P312
HS Code	2933599590

7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one price More Price(17)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	M264670	7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one	199327-61-2	100mg	$95	2021-12-16	Buy
American Custom Chemicals Corporation	CHM0167548	7-METHOXY-6-(3-MORPHOLIN-4-YL-PROPOXY)-3H-QUINAZOLIN-4-ONE 95.00%	199327-61-2	1G	$918.23	2021-12-16	Buy
American Custom Chemicals Corporation	CHM0167548	7-METHOXY-6-(3-MORPHOLIN-4-YL-PROPOXY)-3H-QUINAZOLIN-4-ONE 95.00%	199327-61-2	10G	$4030.95	2021-12-16	Buy
American Custom Chemicals Corporation	CHM0167548	7-METHOXY-6-(3-MORPHOLIN-4-YL-PROPOXY)-3H-QUINAZOLIN-4-ONE 95.00%	199327-61-2	100G	$12647.25	2021-12-16	Buy
AK Scientific	X2633	7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one	199327-61-2	1g	$94	2021-12-16	Buy

Product number	Packaging	Price	Buy
M264670	100mg	$95	Buy
CHM0167548	1G	$918.23	Buy
CHM0167548	10G	$4030.95	Buy
CHM0167548	100G	$12647.25	Buy
X2633	1g	$94	Buy

7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one Chemical Properties,Uses,Production

Description

7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one is a pharmaceutical intermediate used in the preparation of gefitinib, an orally active selective inhibitor of the epidermal growth factor receptor tyrosine kinase, an enzyme that regulates intracellular signalling pathways that associated with the proliferation and survival of cancer cells.

Chemical Properties

White Solid

Uses

Gefitinib intermediate.

7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one Preparation Products And Raw materials

Raw materials

Preparation Products

6-Acetoxy-4-chloro-7-methoxyquinazoline Gefitinib

7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one Suppliers

Global( 275)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Zibo Hangyu Biotechnology Development Co., Ltd	+86-0533-2185556 +8617865335152	Mandy@hangyubiotech.com	China	10986	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29793	60
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1803	55
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21634	55
Hangzhou FandaChem Co.,Ltd.	+8615858145714	FandaChem@Gmail.com	China	8778	55
Nanjing ChemLin Chemical Industry Co., Ltd.	025-83697070	product@chemlin.com.cn	CHINA	3009	60
Shanghai Yingrui Biopharma Co., Ltd.	+86-21-33585366 - 03@	sales03@shyrchem.com	CHINA	738	60
Anqing Chico Pharmaceutical Co., Ltd.	15380796838	chloewu@chicopharm.cn	CHINA	340	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29880	58
NINGBO INNO PHARMCHEM CO., LTD.	13867897135	sales@nbinno.com	CHINA	923	58

Supplier	Advantage
Zibo Hangyu Biotechnology Development Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Beijing Cooperate Pharmaceutical Co.,Ltd	55
Henan Tianfu Chemical Co.,Ltd.	55
Hangzhou FandaChem Co.,Ltd.	55
Nanjing ChemLin Chemical Industry Co., Ltd.	60
Shanghai Yingrui Biopharma Co., Ltd.	60
Anqing Chico Pharmaceutical Co., Ltd.	58
career henan chemical co	58
NINGBO INNO PHARMCHEM CO., LTD.	58

View Lastest Price from 7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-11-26	7-methoxy-6-(3-morpholin-4-yl-propoxy）quinazolin-4(3H)-one 199327-61-2	US $0.00-0.00 / kg	1kg	99%(HPLC)	2tons	Nanjing Fred Technology Co., Ltd
2024-08-27	7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one 199327-61-2	US $110.00-560.00 / g	5g	99%	50	Zibo Hangyu Biotechnology Development Co., Ltd
2021-03-17	7-methoxy-6-(3-morpholin-4-ylpropoxy)-1H-quinazolin-4-one 199327-61-2	US $50.00 / g	10g	99.8%	10tons	Hebei shuoxi biotechnology co. LTD

7-methoxy-6-(3-morpholin-4-yl-propoxy）quinazolin-4(3H)-one
199327-61-2
US $0.00-0.00 / kg
99%(HPLC)
Nanjing Fred Technology Co., Ltd

7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one
199327-61-2
US $110.00-560.00 / g
99%
Zibo Hangyu Biotechnology Development Co., Ltd

7-methoxy-6-(3-morpholin-4-ylpropoxy)-1H-quinazolin-4-one
199327-61-2
US $50.00 / g
99.8%
Hebei shuoxi biotechnology co. LTD

199327-61-2(7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one)Related Search:

Methoxydiethylborane m-Anisyl alcohol p-Anisidine POLY(ETHYLENE GLYCOL) METHYL ETHER ACRYLATE 4-Methoxybenzoic acid

p-Anisaldehyde Anisole Methoxyacetic acid (Trifluoromethoxy)benzene Gefitinib-d6

Gefitinib 6-Hydroxy-7-methoxy-3,4-dihydroquinazolin-4-one 4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol 2-Amino-4-methoxy-5-(3-morpholinopropoxy)benzonitrile 3,4-Dihydro-7-methoxy-4-oxoquinazolin-6-yl acetate

4-(3-Chloropropyl)morpholine Gefitinib Impurity 11 6,7-Dimethoxy-3,4-dihydroquinazoline-4-one

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7-Methoxy-6-(3-Morpholin-4-ylpropoxy) Quinazolin- 4-(3H)-One Gefitinib HCL InterMediates G5 Getitinib interMediate Gefitinib iMpurity F 7-METHOXY-6-(3-MORPHOLINOPROPOXY)QUINAZOLIN-4(3H)-ONE 7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one 7-Methoxy-6-(3-morpholinopropoxy)-3,4-dihydroquinazolin-4-one 7-Methoxy-6-[3-(4-morpholinyl)propoxy]-4(3H)-quinazolinone Gefitinib Impurity 14 7-methoxy-6-(3-morpholin-4-ylpropoxy)-1H-quinazolin-4-one 7-Methoxy-6-(3-morpholin-4-ylpropoxy)quainazolin-4(3H)-one 6-(3-morpholinopropoxy)-7-methoxyquinazolin-4(3H)-one 7-Methoxy-6-(3-morpholinopropoxy) quinazolin-4(3H) 7-Methoxy-6-(3-morpholin-4-yl-propoxy)-3H-quinazolin-4-one 7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin 7-Methoxy-6-[3-(Morpholin-4-yl)propoxy]-3,4-dihydroquinazolin-4-one InterMediate of Gefitinib 7-Methoxy-6-(3-Morpholin-4-yl-propoxy) -4-(3H)-quinazolinone Gefitinib Impurity 17 Gefintinib Impurity 5 Gefitinib-8 4(3H)-Quinazolinone, 7-methoxy-6-[3-(4-morpholinyl)propoxy]- 7-METHOXY-6-(MORPHOLIN-4-YL PROPY L)QUINAZOLIN-4-(3H)-ONE Gefitinib impurities135 Gefitinib impurities132 TIANFU-CHEM - 7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one 7-Methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4(1H)-one 7-methoxy-6- (3-morpholine-4-ylpropyloxy) quinazoline-4 (3H) - one 7-Methoxy-6-(3-morpholinopropoxy)quizolin-4(3H)-one 7-methoxy-6-(4-morpholinobutyl) quinazolin-4(3H)-one [containing < 0.5 % formamide (EC No 200-842-0)] [containing ≥ 0.5 % formamide (EC No 200-842-0) ] 199327-61-2 31936 Gefitinib INTERMEDIATES Heterocycles Intermediates Intermediates & Fine Chemicals Pharmaceuticals