ChemicalBook >> CAS DataBase List >>2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid

2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid

CAS No.
391211-97-5
Chemical Name:
2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid
Synonyms
2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid;3,4-difluoro-2-(2-fluoro-4-iodoanilino)benzoic acid;2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic acid 98%;3,4-Difluoro-2-(2-fluoro-4-iodophenylaMino)benzoic Acid;3,4-Difluoro-2-[(2-fluoro-4-iodophenyl)aMino]benzoic Acid;Benzoic acid, 3,4-difluoro-2-[(2-fluoro-4-iodophenyl)aMino]-;2-(N-2''-FLURO-4''-IODOPHENYL)AMINO-3,4-DIFLUORO BENZOIC ACID;2-(N-2''-FLURO-4''-IODOPHENYL)AMINO-3,4-DIFLUORO BENZOIC ACID;3,4-Difluoro-2-(2-fluoro-4-iodophenylamino)benzoic acid
CBNumber:
CB21507957
Molecular Formula:
C13H7F3INO2
Molecular Weight:
393.1
MDL Number:
MFCD08690072
MOL File:
391211-97-5.mol
Last updated:2024-03-27 11:02:23

2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid Properties

Melting point 189-191°C
Boiling point 370.1±42.0 °C(Predicted)
Density 1.939±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,2-8°C
solubility DMSO (Sparingly), Methanol (Slightly)
form Solid
pka 3.25±0.36(Predicted)
color Off-White to Beige
FDA UNII 5A6V9RGK6M

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P261-P280-P305+P351+P338
HS Code  2916399090

2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid price More Price(20)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC F591960 2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoicAcid 391211-97-5 2g $315 2021-12-16 Buy
Matrix Scientific 099339 3,4-Difluoro-2-((2-fluoro-4-iodophenyl)-amino)benzoic acid 95+% 391211-97-5 1g $353 2021-12-16 Buy
Apolloscientific PC408065 2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoicacid 98% 391211-97-5 1g $286 2021-12-16 Buy
SynQuest Laboratories 4657-K-01 3,4-Difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzoic acid 391211-97-5 1g $295 2021-12-16 Buy
AK Scientific 5091AB 3,4-Difluoro-2-((2-fluoro-4-iodophenyl)amino)benzoicacid 391211-97-5 5g $752 2021-12-16 Buy
Product number Packaging Price Buy
F591960 2g $315 Buy
099339 1g $353 Buy
PC408065 1g $286 Buy
4657-K-01 1g $295 Buy
5091AB 5g $752 Buy

2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid Chemical Properties,Uses,Production

Chemical Properties

Off-White Solid

Uses

Intermediate in the preparation of MEK inhibitors.

Synthesis

To a solution of methyl-3,4-diflluoro-2-((2-flluoro-4-iodophenyl)amino)benzoate (23, 6.0 g, 23.8 mmol) in methanol (80 mL) and water (80 mL) was added LiOH (7.8 g, 195 mmol). The reaction mixture was stirred at 78 C in an oil bath for 1 h. After cooling, the reaction mixture was acidified to pH = 2 with a 2 N HCl solution. The solid was filtered and washed with water to provide 2-(2-Fluoro-4-iodoanilino)-3,4-difluoro benzoic Acid (5.11 g, 96%) as a white solid.
2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid

29632-74-4
61079-72-9
391211-97-5
Synthesis of 2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid from 2-Fluoro-4-iodoaniline and 2,3,4-Trifluorobenzoic acid

2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 96)Suppliers
Supplier Tel Email Country ProdList Advantage
Yangzhou Qinyuan Pharmatech Co.,ltd
+86-18752526868 jennysun@yzqyyykj.com China 81 58
Fluoropharm Co., Ltd.
+86-0571-85586753; +8613336034509 sales@fluoropharm.com China 1376 60
ATK CHEMICAL COMPANY LIMITED
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career henan chemical co
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Accela ChemBio Inc.
+1-858-6993322 info@accelachem.com United States 18028 58
Chongqing Chemdad Co., Ltd
+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39894 58
Shanghai Yingrui Biopharma Co.,Ltd
21-33585366 export01@shyrchem.com CHINA 1319 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
+8613580539051 joe@yuhengpharm.com CHINA 21142 58
AFINE CHEMICALS LIMITED
+86-0571-85134551 sales@afinechem.com China 15352 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418684 +8618949823763 sales@tnjchem.com China 25356 58

View Lastest Price from 2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid pictures 2024-10-31 2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid
391211-97-5
US $0.00 / g 10g 99% 10tons Yangzhou Qinyuan Pharmatech Co.,ltd
	2-(N-2''-FLURO-4''-IODOPHENYL)AMINO-3,4-DIFLUORO BENZOIC ACID pictures 2019-07-06 2-(N-2''-FLURO-4''-IODOPHENYL)AMINO-3,4-DIFLUORO BENZOIC ACID
391211-97-5
US $1.00 / KG 1KG 99% 20kg Career Henan Chemical Co
2-(N-2''-FLURO-4''-IODOPHENYL)AMINO-3,4-DIFLUORO BENZOIC ACID 2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid 3,4-Difluoro-2-(2-fluoro-4-iodophenylaMino)benzoic Acid 3,4-Difluoro-2-[(2-fluoro-4-iodophenyl)aMino]benzoic Acid Benzoic acid, 3,4-difluoro-2-[(2-fluoro-4-iodophenyl)aMino]- 3,4-difluoro-2-(2-fluoro-4-iodoanilino)benzoic acid 2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic acid 98% 2-(N-2''-FLURO-4''-IODOPHENYL)AMINO-3,4-DIFLUORO BENZOIC ACID 3,4-Difluoro-2-(2-fluoro-4-iodophenylamino)benzoic acid 391211-97-5 C13H7F3INO2 Aromatics Intermediates & Fine Chemicals Pharmaceuticals
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