BENACTYZINE HYDROCHLORIDE
- CAS No.
- 57-37-4
- Chemical Name:
- BENACTYZINE HYDROCHLORIDE
- Synonyms
- cedad;fobex;Amizyl;Amisil;amisyl;amizil;cafron;ea2092;katron;parpon
- CBNumber:
- CB2154541
- Molecular Formula:
- C20H26ClNO3
- Molecular Weight:
- 363.88
- MDL Number:
- MFCD00012624
- MOL File:
- 57-37-4.mol
- MSDS File:
- SDS
| Melting point | 177-179 °C(lit.) |
|---|---|
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly, Heated), Methanol (Slightly) |
| form | Solid |
| color | Crystals from Me2CO |
| Merck | 14,1029 |
| CAS DataBase Reference | 57-37-4(CAS DataBase Reference) |
| FDA UNII | 26R628272Q |
| EPA Substance Registry System | Benzeneacetic acid, .alpha.-hydroxy-.alpha.-phenyl-, 2-(diethylamino)ethyl ester, hydrochloride (57-37-4) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301 | |||||||||
| Precautionary statements | P264-P270-P301+P310+P330-P405-P501 | |||||||||
| Hazard Codes | T | |||||||||
| Risk Statements | 23/24/25 | |||||||||
| Safety Statements | 36/37/39-45 | |||||||||
| RIDADR | UN 2811 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | DD2800000 | |||||||||
| HS Code | 2922.50.4000 | |||||||||
| HazardClass | 6.1(b) | |||||||||
| PackingGroup | III | |||||||||
| Toxicity | LD50 orl-rat: 184 mg/kg TXAPA9 1,42,59 | |||||||||
| NFPA 704 |
|
BENACTYZINE HYDROCHLORIDE price More Price(16)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | B0053 | Benactyzine Hydrochloride >98.0%(HPLC)(T) | 57-37-4 | 5g | $172 | 2024-03-01 | Buy |
| TRC | B119600 | Benactyzine Hydrochloride | 57-37-4 | 5g | $110 | 2021-12-16 | Buy |
| Chem-Impex | 37634 | Benactyzinehydrochloride,98%(Assaybytitration,HPLC) 98%(Assaybytitration,HPLC) | 57-37-4 | 5G | $181.44 | 2021-12-16 | Buy |
| ApexBio Technology | C6667 | Benactyzine Hydrochloride | 57-37-4 | 100mg | $60 | 2021-12-16 | Buy |
| ChemScene | CS-8073 | Benactyzine Hydrochloride 99.69% | 57-37-4 | 100mg | $72 | 2021-12-16 | Buy |
BENACTYZINE HYDROCHLORIDE Chemical Properties,Uses,Production
Originator
Suavitil,Merck Sharp and Dohme,US,1957
Uses
Benactyzine Hydrochloride is an antagonist of acetylcholine in the central and peripheral nervous system. Benactyzine Hydrochloride is used as an antispasmodic.
Manufacturing Process
114 parts of ethyl benzilate, 175 parts of β-diethylaminoethanol and 0.2 part of metallic sodium were placed in a flask attached to a total-reflux variable take-off fractionating column. The pressure was reduced to 100 mm and heat was applied by an oil bath the temperature of which was slowly raised to 90°C. During three hours of heating 17 parts of ethanol distilled (35.5°C). When the distillation of the ethanol became slow, the bath temperature was raised to 120°C. When the vapor temperature indicated distillation of the amino alcohol the take off valve was closed and the mixture was refluxed for one hour. At the end of this period the vapor temperature had dropped and two more parts of ethanol were distilled, The remaining aminoalcohol was slowly distilled for three hours. The pressure was then reduced to 20 mm and the remainder of the aminoalcohol distilled at 66°C. During the reaction the color of the solution changed from yellow to deep red. The residue was dissolved in 500 parts of ether, washed once with dilute brine, and three times with water, dried over sodium sulfate and finally dried over calcium sulfate. 500 parts of a saturated solution of HCl in absolute ether was added and the resulting precipitate filtered. Dry HCl gas was passed into the filtrate to a slight excess and the precipitate again filtered. The combined precipitates were washed with cold acetone. The 106 parts of product was purified by recrystallization from acetone as fine white crystals which melt at 177°- 178°C.
Therapeutic Function
Tranquilizer; Anticholinergic
Safety Profile
Poison by ingestion, intraperitoneal, subcutaneous, intradermal, and intravenous routes. Human systemic effects by ingestion of very small amounts: toxic psychosis. Experimental reproductive effects. When heated to decomposition it emits very toxic fumes of NO, and HCl
BENACTYZINE HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9341 | 55 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49391 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569265 +86-18612256290 | 1056@dideu.com | China | 3284 | 58 |
| SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17367 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 9126 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | CHINA | 52867 | 58 |
| Alfa Chemistry | +1-5166625404 | Info@alfa-chemistry.com | United States | 21317 | 58 |
View Lastest Price from BENACTYZINE HYDROCHLORIDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-07-20 | Benactyzine Hydrochloride
57-37-4
|
US $1.00-1.00 / KG | 1g | 99% | 50tons | Shaanxi Dideu Medichem Co. Ltd | |
 |
2020-01-10 | Benactyzine Hydrochloride
57-37-4
|
US $9.80 / KG | 1KG | ≥98% | 20 tons | Career Henan Chemical Co |
-
- Benactyzine Hydrochloride
57-37-4
- US $1.00-1.00 / KG
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-
- Benactyzine Hydrochloride
57-37-4
- US $9.80 / KG
- ≥98%
- Career Henan Chemical Co
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