Polyinosinic-polycytidylic acid sodium salt
- CAS No.
- 42424-50-0
- Chemical Name:
- Polyinosinic-polycytidylic acid sodium salt
- Synonyms
- Poly (I:C) Na;Poly(I:C) sodium;POLY I POLY C, NA;Polymyocyte sodium salt;POLY[I] POLY[C] SODIUM SALT;polyinosinic-polycytidylic acid sodium;polyI-polyC sodium salt compound solution;POLYINOSINIC-POLYCYTIDYLIC ACID SODIUM SALT;Polyinosinicacid-polycytidylicacidsodiumsal;POLYINOSINIC ACID POLYCYTIDYLIC ACID, SODIUM SALT
- CBNumber:
- CB2187556
- Molecular Formula:
- C19H27N7O16P2
- Molecular Weight:
- 671.41
- MDL Number:
- MFCD00131957
- MOL File:
- 42424-50-0.mol
SAFETY
Risk and Safety Statements
Safety Statements | 22-24/25 |
---|---|
WGK Germany | 3 |
RTECS | TR0175000 |
Polyinosinic-polycytidylic acid sodium salt price More Price(17)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | P0913 | Polyinosinic–polycytidylic acid sodium salt ≥99% (less than 1% free nucleotides, TLC) | 42424-50-0 | 10mg | $134 | 2024-03-01 | Buy |
Sigma-Aldrich | P0913 | Polyinosinic–polycytidylic acid sodium salt ≥99% (less than 1% free nucleotides, TLC) | 42424-50-0 | 50mg | $457 | 2024-03-01 | Buy |
Sigma-Aldrich | 528906 | Polyinosinic Acid • Polycytidylic Acid, Sodium Salt, Double-Stranded - CAS 42424-50-0 - Calbiochem Known to induce interferon production. Hypochromicity: ≥40% at 248 nm. Extinction coefficient = 5000 M-1cm-1 at 260 nm, pH 7.0. | 42424-50-0 | 10MG | $115 | 2024-03-01 | Buy |
Sigma-Aldrich | P1530 | Polyinosinic–polycytidylic acid sodium salt TLR ligand tested | 42424-50-0 | 25mg | $210 | 2024-03-01 | Buy |
Sigma-Aldrich | P1530 | Polyinosinic–polycytidylic acid sodium salt TLR ligand tested | 42424-50-0 | 100mg | $627 | 2024-03-01 | Buy |
Polyinosinic-polycytidylic acid sodium salt Chemical Properties,Uses,Production
Uses
Polyinosinic Acid & Polycytidylic Acid Sodium Salt (double-stranded) is a TLR3 (Toll-like receptor 3) agonist.
Uses
TLR3 recognizes double-stranded RNA and is a major effector of the immune response against viral pathogens. Polyinosinic–polycytidylic acid sodium salt is a double-stranded homopolymer used as a model RNA to study cell signaling at the level of TLR3. Poly(IC) is a TRIF-dependent toll-like receptor-3 (TLR3) ligand.
Biological Activity
Polyinosinic-polycytidylic acid sodium (Poly(I:C) sodium) is a synthetic analog of double-stranded RNA and an agonist of toll-like receptor 3 (TLR3) and retinoic acid inducible gene I (RIG-I)-like receptors (RIG-I and MDA5). Polyinosinic-polycytidylic acid sodium can be used as a vaccine adjuvant to enhance innate and adaptive immune responses, and to alter the tumor microenvironment. Polyinosinic-polycytidylic acid sodium can directly trigger cancer cells to undergo apoptosis.
storage
Store at -20°C
Polyinosinic-polycytidylic acid sodium salt Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hangzhou Weitai Biological Pharmaceutical Co.,Ltd. | +8613282012786 | sales@weitai-pharmaceutical.com | China | 61 | 58 |
HangZhou RunYan Pharma Technology Co.,LTD. | +8618882027439 | sales2@runyanpharma.com | China | 302 | 58 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18751 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32161 | 58 |
Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30239 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 22784 | 58 |
Wuhan Fortuna Chemical Co., Ltd | +86-027-59207850 | info@fortunachem.com | China | 5975 | 58 |
View Lastest Price from Polyinosinic-polycytidylic acid sodium salt manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2024-12-18 | Polyinosinic–polycytidylic acid sodium salt ; Poly (I: C); Poly (I:C) Na;
42424-50-0
|
US $0.00-0.00 / kg | 1kg | 90.0%Min. HPLC | 1000kg | HangZhou RunYan Pharma Technology Co.,LTD. | |
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2024-12-13 | Polyinosinic-polycytidylic acid sodium salt
42424-50-0
|
US $0.00 / g | 1g | 45%-55% | 10kg/month | WUHAN FORTUNA CHEMICAL CO., LTD | |
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2024-11-19 | Polyinosinic-polycytidylic acid sodium
42424-50-0
|
US $38.00-88.00 / mg | 10g | TargetMol Chemicals Inc. |
-
- Polyinosinic–polycytidylic acid sodium salt ; Poly (I: C); Poly (I:C) Na;
42424-50-0
- US $0.00-0.00 / kg
- 90.0%Min. HPLC
- HangZhou RunYan Pharma Technology Co.,LTD.
-
- Polyinosinic-polycytidylic acid sodium salt
42424-50-0
- US $0.00 / g
- 45%-55%
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Polyinosinic-polycytidylic acid sodium
42424-50-0
- US $38.00-88.00 / mg
- TargetMol Chemicals Inc.
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