ChemicalBook >> CAS DataBase List >>4-BUTYL-4-[HYDROXYMETHYL]-1,2-DIPHENYL-3,5-PYRAZOLIDINEDIONE HYDROGEN SUCCINATE [ESTER]

4-BUTYL-4-[HYDROXYMETHYL]-1,2-DIPHENYL-3,5-PYRAZOLIDINEDIONE HYDROGEN SUCCINATE [ESTER]

CAS No.
27470-51-5
Chemical Name:
4-BUTYL-4-[HYDROXYMETHYL]-1,2-DIPHENYL-3,5-PYRAZOLIDINEDIONE HYDROGEN SUCCINATE [ESTER]
Synonyms
ae-17;flogos;alfide;solurol;Aflogan;Calibene;SUXIBUZONE;Suxibuzona;lidinedione;Suxibuzonum
CBNumber:
CB2196749
Molecular Formula:
C24H26N2O6
Molecular Weight:
438.47
MDL Number:
MFCD00079562
MOL File:
27470-51-5.mol
Last updated:2024-11-19 20:33:22

4-BUTYL-4-[HYDROXYMETHYL]-1,2-DIPHENYL-3,5-PYRAZOLIDINEDIONE HYDROGEN SUCCINATE [ESTER] Properties

Melting point 126-127°
Boiling point 550.33°C (rough estimate)
Density 1.2847 (rough estimate)
refractive index 1.6300 (estimate)
storage temp. 2-8°C
solubility Practically insoluble in water, freely soluble in acetone, soluble in ethanol (96 per cent), practically insoluble in cyclohexane.
form Solid
pka 4.33±0.17(Predicted)
color White to Off-White
CAS DataBase Reference 27470-51-5
FDA UNII 86TDZ5WP2B
ATC code M02AA22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332
Precautionary statements  P261-P280-P301+P312+P330
Hazard Codes  Xn
Risk Statements  20/21/22
Safety Statements  36
WGK Germany  3
RTECS  WM9640000
Toxicity LD50 orally in mice: 5.683 micromol/kg (Esteve, 1973)

4-BUTYL-4-[HYDROXYMETHYL]-1,2-DIPHENYL-3,5-PYRAZOLIDINEDIONE HYDROGEN SUCCINATE [ESTER] price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S2400000 Suxibuzone European Pharmacopoeia (EP) Reference Standard 27470-51-5 s2400000 $220 2024-03-01 Buy
TRC S880000 Suxibuzone 27470-51-5 100mg $80 2021-12-16 Buy
AK Scientific X6836 Suxibuzone 27470-51-5 100mg $89 2021-12-16 Buy
American Custom Chemicals Corporation API0008442 SUXIBUZONE 95.00% 27470-51-5 100MG $238.35 2021-12-16 Buy
Medical Isotopes, Inc. 48782 Suxibuzone 27470-51-5 5G $2200 2021-12-16 Buy
Product number Packaging Price Buy
S2400000 s2400000 $220 Buy
S880000 100mg $80 Buy
X6836 100mg $89 Buy
API0008442 100MG $238.35 Buy
48782 5G $2200 Buy

4-BUTYL-4-[HYDROXYMETHYL]-1,2-DIPHENYL-3,5-PYRAZOLIDINEDIONE HYDROGEN SUCCINATE [ESTER] Chemical Properties,Uses,Production

Chemical Properties

White or almost white, crystalline powder.

Uses

Suxibuzone is a prodrug of the non steroidal anti inflammatory drug phenylbutazone. It is a drug used for joint and muscular pain.

Uses

analgesic, antipyretic, antiinflammatory

Definition

ChEBI: A pyrazolidine that is phenylbutazone which is substituted by a 3-carboxypropanoylmethyl group at the 4-position. Suxibuzone is a prodrug for phenylbutazone and is commonly used as an anti-inflammatory drug in horses.

brand name

Calibene;Danalon om;Danilon;Flamilon;Flofos.

World Health Organization (WHO)

Suxibuzone, a pyrazolone derivative with anti-inflammatory, analgesic and antipyretic activity, was introduced in 1974 for the treatment of rheumatic disorders. As it is structurally related to phenylbutazone, it is subjected to rigorously restricted indications by some national regulatory authorities. See WHO comment for phenylbutazone.

Biochem/physiol Actions

A prodrug of phenylbutazone.

4-BUTYL-4-[HYDROXYMETHYL]-1,2-DIPHENYL-3,5-PYRAZOLIDINEDIONE HYDROGEN SUCCINATE [ESTER] Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 89)Suppliers
Supplier Tel Email Country ProdList Advantage
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49374 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32161 58
Nextpeptide Inc
+86-0571-81612335 +8613336028439 sales@nextpeptide.com China 19908 58
Coresyn Pharmatech Co., Ltd.
+86-571-86626709 +86-18157142896 cbc@coresyn.com China 9984 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38631 58
SUZHOU SENFEIDA CHEMICAL CO.,LTD
+86-0512-83500002 +8615195660023 sales@senfeida.com China 23046 58
Aceschem Inc.
+1-817863-6948 +1-(817)863-6948 sales@aceschem.com United States 19632 58
Wuhan Topule Biopharmaceutical Co., Ltd
+8618327326525 masar@topule.com China 8467 58
LEAPCHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 43340 58
Shanghai Acmec Biochemical Technology Co., Ltd.
+undefined18621343501 product@acmec-e.com China 33338 58

View Lastest Price from 4-BUTYL-4-[HYDROXYMETHYL]-1,2-DIPHENYL-3,5-PYRAZOLIDINEDIONE HYDROGEN SUCCINATE [ESTER] manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Suxibuzone pictures 2024-11-19 Suxibuzone
27470-51-5
US $30.00-76.00 / mg 99.56% 10g TargetMol Chemicals Inc.
Suxibuzone pictures 2024-11-19 Suxibuzone
27470-51-5
US $30.00-76.00 / mg 99.56% 10g TargetMol Chemicals Inc.
  • Suxibuzone pictures
  • Suxibuzone
    27470-51-5
  • US $30.00-76.00 / mg
  • 99.56%
  • TargetMol Chemicals Inc.
  • Suxibuzone pictures
  • Suxibuzone
    27470-51-5
  • US $30.00-76.00 / mg
  • 99.56%
  • TargetMol Chemicals Inc.
4-BUTYL-4-[HYDROXYMETHYL]-1,2-DIPHENYL-3,5-PYRAZOLIDINEDIONE HYDROGEN SUCCINATE [ESTER] 4-butyl-4-(beta-carboxypropionyl-oxymethyl)-1,2-diphenyl-3,5-pyrazolidinedio 4-butyl-4-hydroxymethyl-1,2-diphenyl-3,5-pyrazolidinedionehydrogensuccinate ae-17 alfide SUXIBUZONE butanedioicacid,mono((4-butyl-3,5-dioxo-1,2-diphenyl-4-pyrazolidinyl)methyl flogos lidinedione solurol succinicacid,monoesterwith4-butyl-4-(hydroxymethyl)-1,2-diphenyl-3,5-pyrazo 3-(1,2-Diphenyl-3,5-dioxo-4-butylpyrazolidine-4-ylmethoxycarbonyl)propionic acid Succinic acid hydrogen (1,2-diphenyl-3,5-dioxo-4-butylpyrazolidin-4-yl)methyl ester Succinic acid hydrogen (4-butyl-3,5-dioxo-1,2-diphenyl-4-pyrazolidinyl)methyl ester Succinic acid hydrogen 1-[(4-butyl-3,5-dioxo-1,2-diphenyl-4-pyrazolidinyl)methyl] ester 3-((4-Butyl-3,5-dioxo-1,2-diphenyl-4-pyrazolidinyl)methoxycarbonyl)propionsaeure 3,5-Pyrazolidinedione, 4-butyl-4-(hydroxymethyl)-1,2-diphenyl-, hydrogen succinate (ester) 4-Butyl-4-(beta-carboxypropionyl-oxymethyl)-1,2-diphenyl-3,5-pyrazolidinedione 4-Hydroxymethylbutazolidine hemisuccinate Aflogan Acetanilide Impurity 1 Suxibuzone CRS Butanedioic acid, 1-[(4-butyl-3,5-dioxo-1,2-diphenyl-4-pyrazolidinyl)methyl] ester 4-((4-butyl-3,5-dioxo-1,2-diphenylpyrazolidin-4-yl)methoxy)-4-oxobutanoic acid Calibene Suxibuzona Suxibuzonum Inhibitor,Suxibuzone,inhibit 1-[3-[2-(dimethylamino)ethyl]-1-[[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]methyl]-1H-indol-5-yl]-N-methylmethanesulfon amide 27470-51-5 Biochemicals and Reagents BioChemical Substrate Analogs Enzyme Inhibitors by Type Enzymes, Inhibitors, and Substrates Enzyme Inhibitors DANILON