ChemicalBook >> CAS DataBase List >>Molsidomine
Molsidomine
- CAS No.
- 25717-80-0
- Chemical Name:
- Molsidomine
- Synonyms
- SIN-10;Coruno;morial;CAS 276;CORVATON;corvasal;Corraton;MOTAZOMIN;SydnopharM;molsidolat
- CBNumber:
- CB2234645
- Molecular Formula:
- C9H14N4O4
- Molecular Weight:
- 242.23
- MDL Number:
- MFCD00869301
- MOL File:
- 25717-80-0.mol
- MSDS File:
- SDS
Last updated:2024-11-19 15:53:33
| Melting point | 140-141°C |
|---|---|
| Boiling point | 385.05°C (rough estimate) |
| Density | 1.3186 (rough estimate) |
| refractive index | 1.6300 (estimate) |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | Sparingly soluble in water, soluble in anhydrous ethanol and in methylene chloride. |
| pka | pK (100°) 3.0 ± 0.1 |
| form | Solid |
| color | White to Off-White |
| λmax | 317nm(MeOH)(lit.) |
| Merck | 14,6234 |
| CAS DataBase Reference | 25717-80-0(CAS DataBase Reference) |
| FDA UNII | D46583G77X |
| ATC code | C01DX12 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P301+P312+P330 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22 | |||||||||
| Safety Statements | 36 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | WU7677400 | |||||||||
| HS Code | 29349990 | |||||||||
| Toxicity | LD50 in male, female mice, male, female rats (mg/kg): 780, 750, 1380, 1350 s.c.; 860, 800, 830, 760 i.v.; 700, 760, 1250, 1250 i.p.; 830, 840, 1050, 1200 orally (Nakaguchi) | |||||||||
| NFPA 704 |
|
Molsidomine price More Price(33)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | M2901 | Molsidomine | 25717-80-0 | 500mg | $91.1 | 2023-01-07 | Buy |
| Sigma-Aldrich | M2901 | Molsidomine | 25717-80-0 | 5g | $522 | 2023-01-07 | Buy |
| TCI Chemical | M2524 | Molsidomine >98.0%(HPLC)(T) | 25717-80-0 | 1g | $48 | 2024-03-01 | Buy |
| TCI Chemical | M2524 | Molsidomine >98.0%(HPLC)(T) | 25717-80-0 | 5g | $141 | 2024-03-01 | Buy |
| Sigma-Aldrich | Y0000821 | Molsidomine European Pharmacopoeia (EP) Reference Standard | 25717-80-0 | y0000821 | $150 | 2024-03-01 | Buy |
Molsidomine Chemical Properties,Uses,Production
Chemical Properties
White to Off-White Solid
Originator
Corvasal,Hoechst
Uses
Molsidomine is an antianginal agent. Molsidomine is an effective therapeutic agents in the treatment of angina pectoris. Molsidomine is a sydnonimine derivative that acts as a heterocyclic direct nitric oxide donor.
Definition
ChEBI: 1-ethoxy-N-[3-(4-morpholinyl)-5-oxadiazol-3-iumyl]methanimidate is a member of morpholines.
Manufacturing Process
1.6 parts by volume of ethyl chloroformate is stirred dropwise into a suspension of 1.0 part by weight of 3-morpholinosydnonimine hydrochloride in 5 parts by volume of pyridine, and the mixture is agitated for a while to allow reaction to take place. Pyridine is removed from the reaction mixture by evaporation, and the residue is dissolved in a small amount of water and extracted with chloroform several times. The extract is dehydrated by adding anhydrous magnesium sulfate and subjected to filtration. Chloroform is removed from the filtrate by distillation, crude crystals being obtained. Recrystallization of the crude crystals from toluene gives 0.6 part by weight of 3-morpholino-N-carboethoxysydnonimine having a melting point of 140°- 141°C. Yield 51%.
brand name
Corvaton (Hoechst-Roussel).
Therapeutic Function
Coronary vasodilator
Molsidomine Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 184)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 5857 | 58 |
| Hebei Weibang Biotechnology Co., Ltd | +8617732866630 | bess@weibangbio.com | China | 18151 | 58 |
| airuikechemical co., ltd. | +86-18353166132 +86-18353166132 | sales02@airuikechemical.com | China | 983 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8618959220845 | sales@amoychem.com | China | 6383 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5906 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49374 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29810 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569262 +86-15319487004 | 1015@dideu.com | China | 3209 | 58 |
View Lastest Price from Molsidomine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-12-24 | molsidomine
25717-80-0
|
US $0.00-0.00 / Kg | 1Kg | 99.9% | 200tons | airuikechemical co., ltd. | |
 |
2024-11-19 | Molsidomine
25717-80-0
|
US $30.00 / mg | 99.96% | 10g | TargetMol Chemicals Inc. | ||
 |
2024-11-19 | Molsidomine
25717-80-0
|
US $30.00 / mg | 99.96% | 10g | TargetMol Chemicals Inc. |
-
- molsidomine
25717-80-0
- US $0.00-0.00 / Kg
- 99.9%
- airuikechemical co., ltd.
-
- Molsidomine
25717-80-0
- US $30.00 / mg
- 99.96%
- TargetMol Chemicals Inc.
-
- Molsidomine
25717-80-0
- US $30.00 / mg
- 99.96%
- TargetMol Chemicals Inc.
ethyl (3-morpholin-4-yl-1-oxa-2-aza-3-azoniacyclopenta-2,4-dien-5-yl)aminoformate
CORVATON
N-Carboxy-3-morpholino-syndone imine ethyl ester
corvasal
SIN-10
n-carboxy-3-morpholinosynonimine ethyl ester
N-(ETHOXYCARBONYL)-3-(4-MORPHOLINO)SYDNONE IMINE
N-[ETHOXYCARBONYL]-3-[4-MORPHOLINYL]SYDNONE IMINE
MOTAZOMIN
MORSIDOMINE
MORSYDOMINE
MOLSIDOMINE
5-[(Ethoxycarbonyl)aMino]-3-(4-Morpholinyl)-1,2,3-oxadiazoliuM Inner Salt
CAS 276
Corraton
Coruno
N-(Ethoxycarbonyl)-3-Morpholinosydnone iMine
SIN 10 (pharMaceutical)
SydnopharM
N-(Ethoxycarbonyl)-3-(4-morpholino)sydnone imine, SIN-10
1-Ethoxy-N-(3-morpholin-4-yl-1-oxa-2-aza-3-azoniacyclopenta-2,4-dien-5-yl)methanimidate
5-Ethoxycarbonyl-3-morpholinosydnonimine
N-(Ethoxycarbonyl)-3-(4-morpholino)syndone imine
N-Ethoxycarbonyl-3-morphalinosydnomine
molsidolat
morial
n-(ethoxycarbonyl)-3-(4-morpholinyl)-sydnoneimin
n-carboxy-3-morpholino-sydnoneiminethylester
n-carboxy-3-morpholinosydnonimineethylester
n-ethoxycarbonyl-3-morpholinosydnonimine
Molsidomine, 98%, Guanylate cyclase activator
(1E)-1-ethoxy-N-[3-(4-morpholinyl)-5-oxadiazol-3-iumyl]methanimidate
Molsidomine>
Molsidomine CRS
Molsidomine USP/EP/BP
(Ethoxycarbonyl)(3-morpholino-1,2,3-oxadiazol-3-ium-5-yl)amide
Molsidomine, ≥ 98.0%
25717-80-0
C9H14N4O4
Nitric Oxide Metabolism
NO Donors
Cell Signaling Enzymes
Biochemicals and Reagents
Application Index
BioChemical
Enzymes, Inhibitors, and Substrates
Nitric Oxide
API