ChemicalBook >> CAS DataBase List >>2-[(6-CHLORO-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)METHYL]BENZONITRILE

2-[(6-CHLORO-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)METHYL]BENZONITRILE

2-[(6-CHLORO-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)METHYL]BENZONITRILE structure

CAS No.: 865758-95-8

Chemical Name:: 2-[(6-CHLORO-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)METHYL]BENZONITRILE

Synonyms: Alogliptin 6-Chloro N-Desmethyl Impurity;Alogliptin-5;ALOGLIPTIN int2;Alogliptin Impurity 08;alogliptin impurities10;alogliptin impurities157;Alogliptin Related Compound 27;Agger coluMn dean interMediates;Benzonitrile, 2-[(6-chloro-3,4-dihydro-2,4-dioxo-1(2H)-pyrim...;2-((6-Chloro-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)methyl)benzonitrile

CBNumber:: CB22452423

Molecular Formula:: C12H8ClN3O2

Molecular Weight:: 261.66

MDL Number:: MFCD09907853

MOL File:: 865758-95-8.mol

Last updated:2024-11-13 18:13:23

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2-[(6-CHLORO-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)METHYL]BENZONITRILE Properties

Density	1.48
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
solubility	Dichloromethane, Ethyl Acetate, Methanol
form	Solid
pka	8.11±0.40(Predicted)
color	White

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P280-P301+P312-P302+P352-P305+P351+P338

2-[(6-CHLORO-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)METHYL]BENZONITRILE price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	C365465	2-((6-Chloro-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)methyl)benzonitrile	865758-95-8	250mg	$1320	2021-12-16	Buy
American Custom Chemicals Corporation	HCH0356880	2-((6-CHLORO-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)METHYL)BENZONITRILE 95.00%	865758-95-8	5MG	$501.02	2021-12-16	Buy
ChemScene	CS-M2294	2-((6-Chloro-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)methyl)benzonitrile	865758-95-8	50mg	$141	2021-12-16	Buy
ChemScene	CS-M2294	2-((6-Chloro-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)methyl)benzonitrile	865758-95-8	100mg	$234	2021-12-16	Buy
Crysdot	CD11041261	2-((6-Chloro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile 95+%	865758-95-8	100mg	$277	2021-12-16	Buy

Product number	Packaging	Price	Buy
C365465	250mg	$1320	Buy
HCH0356880	5MG	$501.02	Buy
CS-M2294	50mg	$141	Buy
CS-M2294	100mg	$234	Buy
CD11041261	100mg	$277	Buy

2-[(6-CHLORO-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)METHYL]BENZONITRILE Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

Alogliptin (A575425) intermediate.

Uses

2-((6-Chloro-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)methyl)benzonitrile is used as a reactant/ intermediate in discovery of Alogliptin (A575425), which is an antidiabetic agent.

2-[(6-CHLORO-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)METHYL]BENZONITRILE synthesis

Synthesis of 2-[(6-CHLORO-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)METHYL]BENZONITRILE from 6-Chlorouracil and 2-Cyanobenzyl bromide

2-[(6-CHLORO-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)METHYL]BENZONITRILE Preparation Products And Raw materials

Raw materials

6-Chlorouracil 2-Cyanobenzyl bromide

Preparation Products

2-[(6-Chloro-3,4-dihydro-3-Methyl-2,4-dioxo-1(2h)-pyriMidinyl)Methyl]benzonitrile

2-[(6-CHLORO-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)METHYL]BENZONITRILE Suppliers

Global( 119)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29858	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28172	58
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14332	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49732	58
Neostar United (Changzhou) Industrial Co., Ltd.	+86-0519-85551759 +8613506123987	marketing1@neostarunited.com	China	8831	58
Chengdu Aslee Biopharmaceuticals, Inc.	28-85305008		CHINA	964	58
SIMAGCHEM CORP	+86-13806087780	sale@simagchem.com	China	17365	58
Hubei Ipure Biology Co., Ltd	+8613367258412	ada@ipurechemical.com	China	10244	58
Shanghai Rochi Pharmaceutical Co.,Ltd.	21-38751876 +8615000076078	info@rochipharma.com	China	431	58
AFINE CHEMICALS LIMITED	+86-0571-85134551	sales@afinechem.com	China	15393	58

Supplier	Advantage
career henan chemical co	58
Hubei Jusheng Technology Co.,Ltd.	58
Standardpharm Co. Ltd.	58
CONIER CHEM AND PHARMA LIMITED	58
Neostar United (Changzhou) Industrial Co., Ltd.	58
Chengdu Aslee Biopharmaceuticals, Inc.	58
SIMAGCHEM CORP	58
Hubei Ipure Biology Co., Ltd	58
Shanghai Rochi Pharmaceutical Co.,Ltd.	58
AFINE CHEMICALS LIMITED	58

View Lastest Price from 2-[(6-CHLORO-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)METHYL]BENZONITRILE manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-04-04	2-[(6-CHLORO-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)METHYL]BENZONITRILE 865758-95-8	US $0.00-0.00 / KG	1KG	98%	1ton	Henan Aochuang Chemical Co.,Ltd.
2025-03-03	Agger coluMn dean interMediates 865758-95-8	US $0.00-0.00 / KG	1KG	98.0%	10000KGS	Shaanxi Dideu New Materials Co. Ltd
2019-07-10	2-[(6-CHLORO-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)METHYL]BENZONITRILE 865758-95-8	US $1.00 / KG	1KG	98%	150KG	Career Henan Chemical Co

2-[(6-CHLORO-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)METHYL]BENZONITRILE
865758-95-8
US $0.00-0.00 / KG
98%
Henan Aochuang Chemical Co.,Ltd.

Agger coluMn dean interMediates
865758-95-8
US $0.00-0.00 / KG
98.0%
Shaanxi Dideu New Materials Co. Ltd

2-[(6-CHLORO-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)METHYL]BENZONITRILE
865758-95-8
US $1.00 / KG
98%
Career Henan Chemical Co

865758-95-8(2-[(6-CHLORO-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)METHYL]BENZONITRILE)Related Search:

Alogliptin Impurity B 2-[(6-Chloro-3,4-dihydro-3-Methyl-2,4-dioxo-1(2h)-pyriMidinyl)Methyl]benzonitrile 2-(AMinoMethyl)benzonitrile hydrochloride Alogliptin benzoate impurity K Benzonitrile, 2-[(tetrahydro-3-Methyl-2,4,6-trioxo-1(2H)-pyriMidinyl)Methyl]-

Alogliptin Related Compound 26 α,α-Dibromo-o-tolunitrile 2-[(6-CHLORO-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)METHYL]BENZONITRILE (R)-2-((3-methyl-2,4-dioxo-6-(piperidin-3-ylamino)-3,4-Dihydro- pyrimidin-1(2H)-yl)methyl)benzonitrile hydrogen chloride Alogliptin Related Compound 18

Alogliptin Impurity 34 Alogliptin Related Compound 32 Alogliptin Impurity 35 Alogliptin Related Compound 21 (R)-2-((6-(3-((3-(2-cyanobenzyl)-1-Methyl-2,6-dioxo-1,2,3,6-tetrahydropyriMidin-4-yl)aMino)piperidin-1-yl)-3-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)Methyl)benzonitrile

Alogliptin Impurity 16 Alogliptin Impurity 10 Alogliptin Related Compound 31

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2-[(6-CHLORO-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)METHYL]BENZONITRILE 2-((6-Chloro-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)methyl)benzonitrile 2-[(6-Chloro-3,4-dihydro-2,4-dioxo-1(2H)-pyriMidinyl)Methyl]-benzonitrile Agger coluMn dean interMediates Benzonitrile, 2-[(6-chloro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)methyl]- Alogliptin Related Compound 27 alogliptin impurities10 alogliptin impurities157 Benzonitrile, 2-[(6-chloro-3,4-dihydro-2,4-dioxo-1(2H)-pyrim... Alogliptin impurity 9/2-((6-Chloro-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)methyl)benzonitrile Alogliptin-5 ALOGLIPTIN int2 Alogliptin 6-Chloro N-Desmethyl Impurity Alogliptin Impurity 08 865758-95-8 895758-95-8