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1-Boc-3-(cyanomethylene)azetidine

1-Boc-3-(cyanomethylene)azetidine Structure
1-Boc-3-(cyanomethylene)azetidine structure
CAS No.
1153949-11-1
Chemical Name:
1-Boc-3-(cyanomethylene)azetidine
Synonyms
tert-butyl 3-(cyanoMethylene)azetidine-1-carboxylate;benzyl 3-(cyanomethylene)azetidine-1-carboxylate;3-Cyanomethylene-azetidine-1-carboxylic acid tert-butyl ester;Baricitinib-013;Baricitinib Impurity 10;tert-Butyl 3-(cyanomethylene);1-Boc-3-(cyanomethylene)azetidine;P-Hydroxy phenyl butanone (Raspberry ketone);1-(tert-Butoxycarbonyl)-3-(cyanomethylene)azetidine;ert-butyl3-(cyanomethylidene)azetidine-1-carboxylate
CBNumber:
CB22485423
Molecular Formula:
C10H14N2O2
Molecular Weight:
194.23
MDL Number:
MFCD12761241
MOL File:
1153949-11-1.mol
MSDS File:
SDS
Last updated:2024-04-06 17:48:18
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1-Boc-3-(cyanomethylene)azetidine Properties

Boiling point 309.7±35.0 °C(Predicted)
Density 1.215
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
form powder to crystal
pka -1.88±0.20(Predicted)
color White to Orange to Green

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
Hazard statements  H301+H311+H331-H315-H319
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
RIDADR  UN 3439 6.1/PG III
HazardClass  6.1
PackingGroup  III
HS Code  2933998090
NFPA 704
0
3 0

1-Boc-3-(cyanomethylene)azetidine price More Price(20)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical B5217 1-(tert-Butoxycarbonyl)-3-(cyanomethylene)azetidine >95.0%(GC) 1153949-11-1 200mg $52 2024-03-01 Buy
TCI Chemical B5217 1-(tert-Butoxycarbonyl)-3-(cyanomethylene)azetidine >95.0%(GC) 1153949-11-1 1g $148 2024-03-01 Buy
TRC B117850 1-(tert-Butoxycarbonyl)-3-(cyanomethylene)azetidine 1153949-11-1 1g $45 2021-12-16 Buy
TRC B117850 1-(tert-Butoxycarbonyl)-3-(cyanomethylene)azetidine 1153949-11-1 25g $340 2021-12-16 Buy
Apolloscientific OR930876 tert-Butyl3-(cyanomethylene)azetidine-1-carboxylate 95% 1153949-11-1 10g $135 2021-12-16 Buy
Product number Packaging Price Buy
B5217 200mg $52 Buy
B5217 1g $148 Buy
B117850 1g $45 Buy
B117850 25g $340 Buy
OR930876 10g $135 Buy

1-Boc-3-(cyanomethylene)azetidine Chemical Properties,Uses,Production

Uses

1-(tert-Butoxycarbonyl)-3-(cyanomethylene)azetidine is used in the synthesis of baricitinib via Horner-Emmons reaction of tert-butyl-oxoazetidine-carboxylate followed by sulfonamidation, nucleophilic addition. and subsequent Suzuki-coupling reaction.

Uses

1-(tert-Butoxycarbonyl)-3-(cyanomethylene)azetidine is used in the synthesis of baricitinib via Horner-Emmons reaction of tert-butyl-oxoazetidine-carboxylate followed by sulfonamidation, nucleophilic addition. and subsequent Suzuki-coupling reaction.

1-Boc-3-(cyanomethylene)azetidine Preparation Products And Raw materials

Raw materials

Preparation Products

1-Boc-3-(cyanomethylene)azetidine Suppliers

Global( 204)Suppliers
Supplier Tel Email Country ProdList Advantage
Firsky International Trade (Wuhan) Co., Ltd 		+8615387054039 admin@firsky-cn.com China 427 58
Hangzhou ICH Biofarm Co., Ltd 		+86-0571-28186870; +undefined8613073685410 sales@ichemie.com China 1001 58
Henan Fengda Chemical Co., Ltd 		+86-371-86557731 +86-13613820652 info@fdachem.com China 20285 58
Beijing Cooperate Pharmaceutical Co.,Ltd 		010-60279497 sales01@cooperate-pharm.com CHINA 1803 55
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21634 55
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32957 60
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29880 58
Shenzhen Nexconn Pharmatechs Ltd 		+86-755-89396905 +86-15013857715 admin@nexconn.com China 10311 58
Jinan Carbotang Biotech Co.,Ltd. 		+8615866703830 figo.gao@foxmail.com China 8497 58
Chengdu Pukang Biotechnology Co., Ltd 		028-82550498 export@pu-kang.com CHINA 210 58
Supplier Advantage
Firsky International Trade (Wuhan) Co., Ltd 		58
Hangzhou ICH Biofarm Co., Ltd 		58
Henan Fengda Chemical Co., Ltd 		58
Beijing Cooperate Pharmaceutical Co.,Ltd 		55
Henan Tianfu Chemical Co.,Ltd. 		55
ATK CHEMICAL COMPANY LIMITED 		60
career henan chemical co 		58
Shenzhen Nexconn Pharmatechs Ltd 		58
Jinan Carbotang Biotech Co.,Ltd. 		58
Chengdu Pukang Biotechnology Co., Ltd 		58

View Lastest Price from 1-Boc-3-(cyanomethylene)azetidine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-Boc-3-(cyanomethylene)azetidine pictures 2024-11-26 1-Boc-3-(cyanomethylene)azetidine
1153949-11-1
 US $0.00-0.00 / kg 1kg 98% 1 ton Nanjing Fred Technology Co., Ltd
tert-butyl 3-(cyanomethylidene)azetidine-1-carboxylate pictures 2024-04-06 tert-butyl 3-(cyanomethylidene)azetidine-1-carboxylate
1153949-11-1
 US $880.00 / g 1g 98 500 Kg R&D Scientific Inc.
1-Boc-3-(cyanomethylene)azetidine pictures 2023-12-23 1-Boc-3-(cyanomethylene)azetidine
1153949-11-1
 US $500.00 / KG 1KG 99% 2000 ton/year Henan Fengda Chemical Co., Ltd

1-Boc-3-(cyanomethylene)azetidine Spectrum

1-Boc-3-(cyanomethylene)azetidine(1153949-11-1)1HNMR

1153949-11-1(1-Boc-3-(cyanomethylene)azetidine)Related Search:

3,5-Dimethyl-piperazine-1-carboxylic acid tert-butyl ester 1-N-Boc-3-hydroxyazetidine (R)-1-Boc-2-cyanopyrrolidine tert-butyl 4-(2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)Methyl)benzoyl)piperazine-1-carboxylate 4-[6-(6-BROMO-8-CYCLOPENTYL-5-METHYL-7-OXO-7,8-DIHYDRO-PYRIDO[2,3-D]PYRIMIDIN-2-YLAMINO)-PYRIDIN-3-YL]-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
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tert-butyl 3-oxidanyl-3-pyridin-2-yl-azetidine-1-carboxylate tert-butyl 4-((4'-chloro-5,5-diMethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)Methyl)piperazine-1-carboxylate 1-Boc-Azetidine-3-yl-methanol tert-Butyl 4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]piperidine-1-carboxylate tert-butyl 2,2,4,8-tetraMethyl-1,2,3,4-tetrahydroquinolin-7-ylcarbaMate
tert-butyl 3-(4-(7-carbamoyl-2H-indazol-2-yl)phenyl)piperidine-1-carboxylate tert-butyl 2-(1-(3,4-difluoro-2-((2-fluoro-4-iodophenyl)aMino)benzoyl)-3-hydroxyazetidin-3-yl)piperidine-1-carboxylate tert-butyl 2-(3-hydroxy-1-(2,2,2-trifluoroacetyl)azetidin-3-yl)piperidine-1-carboxylate

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1-Boc-3-(cyanomethylene)azetidine tert-butyl 3-(cyanoMethylidene)azetidine-1-carboxylate 3-(Cyanomethylene)-1-azetidinecarboxylic acid tert-butyl ester 1-(tert-Butoxycarbonyl)-3-(cyanomethylene)azetidine P-Hydroxy phenyl butanone (Raspberry ketone) tert-Butyl 3-(cyanomethylene) 1-(tert-Butoxycarbonyl)-3-(cyanomethylene)azetidine 1-Azetidinecarboxylic acid, 3-(cyanomethylene)-, 1,1-dimethylethyl ester Baricitinib Impurity 10 Baricitinib-013 benzyl 3-(cyanomethylene)azetidine-1-carboxylate tert-butyl 3-(cyanoMethylene)azetidine-1-carboxylate 3-Cyanomethylene-azetidine-1-carboxylic acid tert-butyl ester ert-butyl3-(cyanomethylidene)azetidine-1-carboxylate 1153949-11-1