Mitoquinone mesylate
- CAS No.
- 845959-50-4
- Chemical Name:
- Mitoquinone mesylate
- Synonyms
- MitoQ;MitoQ mesylate;MitoQ10 mesylate;Mitoquinol Mesylate;Mitoquinone mesylate;Mitoquinone mesylate (MitoQ);Mitoquinone (MitoQ10) mesylate;MitoQ mesylate|||MitoQ10 mesylate;Mitoquinone mesylate, 10 mM in DMSO;Mitoquinone mesylate, ethanol solution
- CBNumber:
- CB22505185
- Molecular Formula:
- C38H47O7PS
- Molecular Weight:
- 678.814341
- MDL Number:
- MFCD30747833
- MOL File:
- 845959-50-4.mol
- MSDS File:
- SDS
| storage temp. | -20°C |
|---|---|
| solubility | Soluble in DMSO. |
| form | waxy solid |
| color | Orange |
| Stability | Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
| FDA UNII | 6E01CG547T |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H319 | |||||||||
| Precautionary statements | P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501 | |||||||||
| NFPA 704 |
|
Mitoquinone mesylate price More Price(11)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 29317 | Mitoquinone (mesylate) | 845959-50-4 | 1mg | $29 | 2024-03-01 | Buy |
| Cayman Chemical | 29317 | Mitoquinone (mesylate) | 845959-50-4 | 25mg | $246 | 2024-03-01 | Buy |
| Cayman Chemical | 29317 | Mitoquinone (mesylate) | 845959-50-4 | 5mg | $78 | 2024-03-01 | Buy |
| Cayman Chemical | 29317 | Mitoquinone (mesylate) | 845959-50-4 | 10mg | $141 | 2024-03-01 | Buy |
| TRC | M372215 | MitoquinoneMesylate | 845959-50-4 | 10mg | $180 | 2021-12-16 | Buy |
Mitoquinone mesylate Chemical Properties,Uses,Production
Description
Mitoquinone mesylate (845959-50-4) is a mitochondria-targeted antioxidant.? Displays cardio- and neuroprotective effects.1 Displays beneficial effects in mouse models of Alzheimer’s disease.2,3 Protects pancreatic β-cells against oxidative stress and improves insulin secretion.4 Inhibits respiratory syncytial virus (RSV) production via lowering of mitochondrial ROS levels.5 Cell permeable.
Uses
Mitoquinone Mesylate is used in the transport and metabolism of some cationic ubiquinone antioxidants.
in vivo
Mitoquinone (MitoQ) treatment significantly reduces pancreatic oedema and neutrophil infiltration. MitoQ dose-dependently increases serum amylase with an approximate doubling at the higher dose. MitoQ treatment nearly doubles lung MPO activity induced by Caerulein with a significant increase of serum IL-6 levels also evident at 10 mg/kg (dose 1)[2].
References
1.Ghosh et al. (2010), Neuroprotection by a mitochondria-targeted drug in a Parkinson’s disease model; Free Radic. Biol. Med., 49 1674
2.McManus et al. (2011), The mitochondria-targeted antioxidant MitoQ prevents loss of spatial memory retention and early neuropathology in a transgenic mouse model of Alzheimer’s disease; J. Neurosci., 31 15703
3.Young and Franklin, (2019), The mitochondria-targeted antioxidant MitoQ inhibits memory loss, neuropathology, and extends lifespan in aged 3xTg-AD mice; Cell Neurosci. 101 103409
4.Lim et al. (2011), Mitochondria-targeted antioxidants protect pancreatic b-cells against oxidative stress and improve insulin secretion in glucotoxicity and glucolipotoxicity; Cell Physiol. Biochem., 28 873
5.MengJie et al. (2019), Subversion of Host Cell Mitochondria by RSV to Favor Virus Production in Dependent on Inhibition of Mitochondrial Complex I and ROS Generation; Cells 8 1417
Mitoquinone mesylate Preparation Products And Raw materials
Raw materials
Preparation Products
Mitoquinone mesylate Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou Hyper Chemicals Limited | +86-0086-57187702781 +8613675893055 | info@hyper-chem.com | China | 295 | 58 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | FandaChem@Gmail.com | China | 3237 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29808 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32159 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10473 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8467 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43340 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501; +undefined18621343501 | product@acmec-e.com | China | 33338 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 |
View Lastest Price from Mitoquinone mesylate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-01 | Mitoquinone mesylate
845959-50-4
|
US $0.00-0.00 / KG | 1KG | 99% | 5,000KG | Hangzhou Hyper Chemicals Limited | |
 |
2020-01-02 | Mitoquinone mesylate
845959-50-4
|
US $1.00 / KG | 1KG | Min98% HPLC | g/kg/ton | Career Henan Chemical Co |
-
- Mitoquinone mesylate
845959-50-4
- US $0.00-0.00 / KG
- 99%
- Hangzhou Hyper Chemicals Limited
-
- Mitoquinone mesylate
845959-50-4
- US $1.00 / KG
- Min98% HPLC
- Career Henan Chemical Co