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ChemicalBook >> CAS DataBase List >>(E)-(4R,9aS)-7-[3-Methoxy-4-(4-methyl-1H-imidazol-1-yl)benzylidene]-4-(3,4,5-trifluorophenyl)hexahydropyrido[2,1-c][1,4]oxazin-6-one

(E)-(4R,9aS)-7-[3-Methoxy-4-(4-methyl-1H-imidazol-1-yl)benzylidene]-4-(3,4,5-trifluorophenyl)hexahydropyrido[2,1-c][1,4]oxazin-6-one

(E)-(4R,9aS)-7-[3-Methoxy-4-(4-methyl-1H-imidazol-1-yl)benzylidene]-4-(3,4,5-trifluorophenyl)hexahydropyrido[2,1-c][1,4]oxazin-6-one Structure
(E)-(4R,9aS)-7-[3-Methoxy-4-(4-methyl-1H-imidazol-1-yl)benzylidene]-4-(3,4,5-trifluorophenyl)hexahydropyrido[2,1-c][1,4]oxazin-6-one structure
CAS No.
937812-80-1
Chemical Name:
(E)-(4R,9aS)-7-[3-Methoxy-4-(4-methyl-1H-imidazol-1-yl)benzylidene]-4-(3,4,5-trifluorophenyl)hexahydropyrido[2,1-c][1,4]oxazin-6-one
Synonyms
HYR-141;Otamixaban;SynonyMs: HYR-141;γ-Secretase Modulators;γ-Secretase Modulators;gaMMa-Secretase Modulators;AMyloid-β production inhibitor;Amyloid-β production inhibitor;gammaSecretase Modulators,gamma Secretase Modulators;(E)-(4R,9AS)-7-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)benzylidene]-4-(3,4,5-trifluorophenyl)h
CBNumber:
CB22509981
Molecular Formula:
C26H24F3N3O3
Molecular Weight:
483.48
MDL Number:
MFCD13184813
MOL File:
937812-80-1.mol
Last updated:2024-07-02 08:55:03
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(E)-(4R,9aS)-7-[3-Methoxy-4-(4-methyl-1H-imidazol-1-yl)benzylidene]-4-(3,4,5-trifluorophenyl)hexahydropyrido[2,1-c][1,4]oxazin-6-one Properties

Boiling point 682.5±55.0 °C(Predicted)
Density 1.37
storage temp. Store at -20°C
solubility Soluble in DMSO
form Powder
pka 5.76±0.61(Predicted)
color White to off-white
FDA UNII S173RED00L

(E)-(4R,9aS)-7-[3-Methoxy-4-(4-methyl-1H-imidazol-1-yl)benzylidene]-4-(3,4,5-trifluorophenyl)hexahydropyrido[2,1-c][1,4]oxazin-6-one price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0346 gamma-SecretaseModulators 99.66% 937812-80-1 10mg $1171 2021-12-16 Buy
Matrix Scientific 143735 (E)-(4R,9AS)-7-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)benzylidene]-4-(3,4,5-trifluorophenyl)hexahydropyrido[2,1-c][1,4]oxazin-6-one 95% 937812-80-1 1g $3330 2021-12-16 Buy
Matrix Scientific 143735 (E)-(4R,9AS)-7-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)benzylidene]-4-(3,4,5-trifluorophenyl)hexahydropyrido[2,1-c][1,4]oxazin-6-one 95% 937812-80-1 5g $6476 2021-12-16 Buy
AK Scientific 3690AH Gamma-secretasemodulators 937812-80-1 5g $8792 2021-12-16 Buy
ChemScene CS-0346 gamma-SecretaseModulators 99.66% 937812-80-1 5mg $604 2021-12-16 Buy
Product number Packaging Price Buy
CS-0346 10mg $1171 Buy
143735 1g $3330 Buy
143735 5g $6476 Buy
3690AH 5g $8792 Buy
CS-0346 5mg $604 Buy

(E)-(4R,9aS)-7-[3-Methoxy-4-(4-methyl-1H-imidazol-1-yl)benzylidene]-4-(3,4,5-trifluorophenyl)hexahydropyrido[2,1-c][1,4]oxazin-6-one Chemical Properties,Uses,Production

Uses

A potent (Ki = 0.5 nM), selective, rapid acting, competitive and reversible fXa inhibitor that effectively inhibits both free and prothrombinase-bound fXa. Clinical studies show that it is efficacious, safe and well tolerated in humans and therefore has considerable potential for the treatment of acute coronary syndrome.

(E)-(4R,9aS)-7-[3-Methoxy-4-(4-methyl-1H-imidazol-1-yl)benzylidene]-4-(3,4,5-trifluorophenyl)hexahydropyrido[2,1-c][1,4]oxazin-6-one Preparation Products And Raw materials

Raw materials

Preparation Products

(E)-(4R,9aS)-7-[3-Methoxy-4-(4-methyl-1H-imidazol-1-yl)benzylidene]-4-(3,4,5-trifluorophenyl)hexahydropyrido[2,1-c][1,4]oxazin-6-one Suppliers

Global( 32)Suppliers
Supplier Tel Email Country ProdList Advantage
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49392 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207 sales@molcore.com China 49739 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 52927 58
Chembest Research Laboratories Limited +86-21-20908456 sales@BioChemBest.com China 6008 61
Haoyuan Chemexpress Co., Ltd. 021-58950125 info@chemexpress.com China 7553 61
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn United States 4863 58
CEG Chemical Science&Technology Co., Ltd. Mobile:13665161512 China 1785 58
Musechem +1-800-259-7612 info@musechem.com United States 4662 60
Shanghai Zeye Biotechnology Co., Ltd. 021-61998551 13122364865 sale1@shzysw.net China 9772 58
Supplier Advantage
CONIER CHEM AND PHARMA LIMITED 		58
TargetMol Chemicals Inc. 		58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		58
Aladdin Scientific 		58
Chembest Research Laboratories Limited 61
Haoyuan Chemexpress Co., Ltd. 61
MedChemexpress LLC 58
CEG Chemical Science&Technology Co., Ltd. 58
Musechem 60
Shanghai Zeye Biotechnology Co., Ltd. 58

937812-80-1((E)-(4R,9aS)-7-[3-Methoxy-4-(4-methyl-1H-imidazol-1-yl)benzylidene]-4-(3,4,5-trifluorophenyl)hexahydropyrido[2,1-c][1,4]oxazin-6-one)Related Search:

Rivaroxaban Abiraterone
(E)-(4R,9aS)-7-[3-Methoxy-4-(4-methyl-1H-imidazol-1-yl)benzylidene]-4-(3,4,5-trifluorophenyl)hexahydropyrido[2,1-c][1,4]oxazin-6-one HYR-141 Otamixaban SynonyMs: HYR-141 gaMMa-Secretase Modulators AMyloid-β production inhibitor γ-Secretase Modulators Pyrido[2,1-c][1,4]oxazin-6(1H)-one, hexahydro-7-[[3-Methoxy-4-(4-Methyl-1H-iMidazol-1-yl)phenyl]Methylene]-4-(3,4,5-trifluorophenyl)-, (4R,7E,9aS)- hexahydro-7-[[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]methylene]-4-(3,4,5-trifluorophenyl)-(4R,7E,9aS)-Pyrido[2,1-c][1,4]oxazin-6(1H)-one (E)-(4R,9AS)-7-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)benzylidene]-4-(3,4,5-trifluorophenyl)h γ-Secretase Modulators Amyloid-β production inhibitor gammaSecretase Modulators,gamma Secretase Modulators 937812-80-1