(2E,4E,6Z)-3-Methyl-7-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-3-propoxy-3-naphthalenyl)-2,4,6-octatrienoicacid
- CAS No.
- 180713-37-5
- Chemical Name:
- (2E,4E,6Z)-3-Methyl-7-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-3-propoxy-3-naphthalenyl)-2,4,6-octatrienoicacid
- Synonyms
- CD 3159;UVI 2112;LG 100754;LG100754 >=98% (HPLC);(2E,4E,6Z)-3-Methyl-7-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-3-propoxy-3-naphthalenyl)-2,4,6-octatrienoicacid;(2E,4E,6Z)-3-Methyl-7-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-3-propoxy-2-naphthalenyl)-2,4,6-Octatrienoic acid;2,4,6-Octatrienoic acid, 3-methyl-7-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-3-propoxy-2-naphthalenyl)-, (2E,4E,6Z)-
- CBNumber:
- CB22518831
- Molecular Formula:
- C26H36O3
- Molecular Weight:
- 396.56
- MDL Number:
- MFCD00951259
- MOL File:
- 180713-37-5.mol
- MSDS File:
- SDS
(2E,4E,6Z)-3-Methyl-7-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-3-propoxy-3-naphthalenyl)-2,4,6-octatrienoicacid Properties
Boiling point | 549.4±50.0 °C(Predicted) |
---|---|
Density | 1.003±0.06 g/cm3(Predicted) |
storage temp. | Store at -20°C |
solubility | DMSO: soluble10mg/mL, clear |
pka | 4.74±0.33(Predicted) |
form | powder |
color | white to beige |
(2E,4E,6Z)-3-Methyl-7-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-3-propoxy-3-naphthalenyl)-2,4,6-octatrienoicacid price More Price(18)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | SML0771 | LG100754 ≥98% (HPLC) | 180713-37-5 | 5mg | $134 | 2024-03-01 | Buy |
Sigma-Aldrich | SML0771 | LG100754 ≥98% (HPLC) | 180713-37-5 | 25mg | $325.8 | 2024-03-01 | Buy |
Cayman Chemical | 19647 | LG 100754 ≥98% | 180713-37-5 | 1mg | $32 | 2024-03-01 | Buy |
Cayman Chemical | 19647 | LG 100754 ≥98% | 180713-37-5 | 5mg | $116 | 2024-03-01 | Buy |
Cayman Chemical | 19647 | LG 100754 ≥98% | 180713-37-5 | 10mg | $214 | 2024-03-01 | Buy |
(2E,4E,6Z)-3-Methyl-7-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-3-propoxy-3-naphthalenyl)-2,4,6-octatrienoicacid Chemical Properties,Uses,Production
Description
LG 100754 is a ligand of retinoid X receptor (RXR) that modulates the activity of RXR dimers. It acts as an antagonist towards RXR homodimers but as an agonist of heterodimers consisting of RXR and retinoic acid receptor (RAR) or PPARs. LG 100754, at 1 μM, is a weak agonist of RXR-PPARγ but strongly enhances signaling through the heterodimer in response to PPARγ ligands, including rosiglitazone and 15-deoxy-Δ12,14-prostaglandin J2 . Through this action, LG 100754 decreases glucose levels and relieves insulin resistance in mice.
Uses
LG 100754 is a novel RXR:PPARγ agonist and decreases glucose levels in vivo. It can also be used in compositions comprising anti-androgen and anti-thyroid agents and kits for diagnosis and treatment of viral respiratory infection.
(2E,4E,6Z)-3-Methyl-7-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-3-propoxy-3-naphthalenyl)-2,4,6-octatrienoicacid Preparation Products And Raw materials
Raw materials
Preparation Products
(2E,4E,6Z)-3-Methyl-7-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-3-propoxy-3-naphthalenyl)-2,4,6-octatrienoicacid Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
Dalian Meilun Biotech Co., Ltd. | 0411-62910999 13889544652 | meilunui@163.com | China | 4670 | 58 |
EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8449 | 60 |
Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9707 | 58 |
BOC Sciences | -- | info@bocsci.com | USA | 0 | 65 |
ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8141 | 58 |
Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44941 | 58 |