ChemicalBook >> CAS DataBase List >>8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione
8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione
- CAS No.
- 666816-98-4
- Chemical Name:
- 8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione
- Synonyms
- 8-Bromo-7-(2-butyn-1-yl)-3-methylxanthine;8-broMo-7-(but-2-yn-1-yl)-3-Methyl-1H-purine-2,6(3H,7H)-dione;8-Bromo-7-(2-butynyl)-3,7-dihydro-3-methyl-1H-purine-2,6-dione;3-Methyl-7-(2-butyn-1-yl)-8-bromoxanthine 8-Bromo-7-(2-butynyl)-3,7-dihydro-3-methyl-1H-purine-2,6-dione;Linagliptin INT1;8-BROMO-7-(BUT-2-YNYL);Linagliptin Impurity 36;Linagliptin Impurity 73;Iinagliptin Intermediate2;Linagliptin interMediateC
- CBNumber:
- CB22538943
- Molecular Formula:
- C10H9BrN4O2
- Molecular Weight:
- 297.11
- MDL Number:
- MFCD22126091
- MOL File:
- 666816-98-4.mol
Last updated:2024-07-29 15:17:36
Melting point | 285 °C |
---|---|
Density | 1.71 |
storage temp. | 2-8°C |
solubility | DMSO (Slightly), Methanol (Slightly) |
form | powder to crystal |
pka | 8.91±0.70(Predicted) |
color | White to Almost white |
LogP | 1.25 at 20℃ |
CAS DataBase Reference | 666816-98-4 |
8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione price More Price(20)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TCI Chemical | B4454 | 8-Bromo-7-(2-butyn-1-yl)-3-methylxanthine >98.0%(HPLC)(T) | 666816-98-4 | 200mg | $103 | 2024-03-01 | Buy |
TCI Chemical | B4454 | 8-Bromo-7-(2-butyn-1-yl)-3-methylxanthine >98.0%(HPLC)(T) | 666816-98-4 | 1g | $334 | 2023-01-07 | Buy |
TRC | B687605 | 8-Bromo-3-methyl-7-(2-butynyl)-xanthine | 666816-98-4 | 100mg | $65 | 2021-12-16 | Buy |
Chem-Impex | 43531 | 8-Bromo-7-(2-butyn-1-yl)-3-methylxanthine,≥98%(HPLC) ≥98%(HPLC) | 666816-98-4 | 200MG | $107.46 | 2021-12-16 | Buy |
Matrix Scientific | 096910 | 8-Bromo-7-(but-2-yn-1-yl)-3-methyl-1H-purine-2,6(3H,7H)-dione 95+% | 666816-98-4 | 1g | $19 | 2021-12-16 | Buy |
8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione Chemical Properties,Uses,Production
Chemical Properties
White powder
Synthesis
8-bromo-3-methyl-3,7-dihydro-1H-purine-2,6-dione (2.450 g, 10 mmol),1-bromo-2-butyne (1.596 g, 12 mmol), Sodium carbonate (1.590 g, 15 mmol), and 20mL of acetone was added to a 100mL flask. The reaction system was heated to 40 ° C, and the reaction was stirred for 4h. After the reaction was cooled to room temperature, suction filtration was performed, and the filter cake was washed with methanol to obtain a crude product as a pale yellow solid. The crude product was reconstituted with dichloromethane and cyclohexane. Yield 2.912 g of 8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione. The yield was 98%, and the purity was 99.9%.
![93703-24-3](/CAS/GIF/93703-24-3.gif)
![3355-28-0](/CAS/GIF/3355-28-0.gif)
![666816-98-4](/CAS/GIF/666816-98-4.gif)
Synthesis of 8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione from 8-Bromo-3-methyl-xanthine and 1-BROMO-2-BUTYNE
8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione Preparation Products And Raw materials
Global( 404)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Shanghai Joiny Pharmaceutical Co.,LTD | +8613681955282 | gyd@joiny-pharma.com | China | 249 | 58 |
Sinoway Industrial co., ltd. | 0592-5800732; +8613806035118 | xie@china-sinoway.com | China | 990 | 58 |
Anhui Ruihan Technology Co., Ltd | +8617756083858 | daisy@anhuiruihan.com | China | 994 | 58 |
Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 | sales@frappschem.com | China | 885 | 50 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1811 | 55 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21668 | 55 |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9332 | 55 |
Shanghai Yingrui Biopharma Co., Ltd. | +86-21-33585366 - 03@ | sales03@shyrchem.com | CHINA | 738 | 60 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32760 | 60 |
View Lastest Price from 8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2024-08-22 | 8-Bromo-7-But-2-Ynyl-3-Methyl-Purine-2,6-Dione / Linagliptin Intermediate
666816-98-4
|
US $0.00-0.00 / kg | 1kg | 99% | 20tons | Sinoway Industrial co., ltd. | |
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2024-06-14 | 8-Bromo-7-(2-butynyl)-3,7-dihydro-3-methyl-1H-purine-2,6-dione
666816-98-4
|
US $0.00 / kg | 1kg | 98% | hundreds of kgs | Shanghai Joiny Pharmaceutical Co.,LTD | |
![]() |
2024-05-09 | 8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione
666816-98-4
|
US $0.00-0.00 / kg | 1kg | 98% | 1 ton | Nanjing Fred Technology Co., Ltd |
-
- 8-Bromo-7-But-2-Ynyl-3-Methyl-Purine-2,6-Dione / Linagliptin Intermediate
666816-98-4
- US $0.00-0.00 / kg
- 99%
- Sinoway Industrial co., ltd.
-
- 8-Bromo-7-(2-butynyl)-3,7-dihydro-3-methyl-1H-purine-2,6-dione
666816-98-4
- US $0.00 / kg
- 98%
- Shanghai Joiny Pharmaceutical Co.,LTD
-
- 8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione
666816-98-4
- US $0.00-0.00 / kg
- 98%
- Nanjing Fred Technology Co., Ltd
666816-98-4(8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione)Related Search:
Linagliptin impurity 15
(1R trans)-2-(3,4-difluorophenyl)cyclopropane amine
Tetrahydro-2,2-dimethyl-4,7-methano-6H-1,3-dioxolo[4,5-d][1,2]oxazine-6-carboxylic acid phenylmethyl ester
Canagliflozin
Cyclopropanamine,2-(3,4-difluorophenyl)-(1R,2S) -(2R,3R)-2,3-dihydroxybutanedioate (1:1)
Rivaroxaban
3-(R)-Piperidinyl PhthaliMide D-(-)-tartaric acid
Linagliptin
5-Acetyl Rhein
1,1'-[(5E)-5-Methyl-7-oxo-5-undecene-1,11-diyl] Bis
1of4
8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione
8-broMo-7-(but-2-ynyl)-3-Methyl-3,7-dihydropurine-2,6-dione
3-Methyl-7-(2-butyn-1-yl)-8-bromoxanthine
8-broMo-7-but-2-yn-1-yl-3-Methyl-3,7-dihydro-1H-purine-2,6-dione
8-BroMo-7-(2-butyn-a-yl)-3,7-dihydro-3-Methyl-1-1H-purine-2,6-dione
Linagliptin interMediateC
(R)-tert-butyl 1-(7-(but-2-ynyl)-3-Methyl-1-((4-Methylquinazolin-2-yl)Methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-ylcarbaMate
3-Methyl-7-(2-butin-1-yl)-8-broMoxanthine
1H-Purine-2,6-dione, 8-broMo-7-(2-butynyl)-3,7-dihydro-3-Methyl-
Iinagliptin Intermediate2
Linagliptin INT1
8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione/3-Methyl-7-(2-butyn-1-yl)-8-bromoxanthine
8-Bromo-7-(2- butynyl)-3,7-dihydro- 3-methyl-1H-pur ine-2,6-dion
8-BROMO-7-(BUT-2-YNYL)
8-bromo-7-(but-2-ynyl)-3-methyl-3,4,5,7-tetrahydro-1H-purine-2,6-dione
8-Bromo-7-(but-2-yn-1-yl)-3-methyl-1H-purine-2,6(3H
8- bromo -7-(2- butyne)-3- methyl xanthine
8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2
8-bromo-7-(2-butynyl)-3,7-dihydro-3-methyl-1H-indole-2,6-dione
Linagliptin Impurity 36
8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dion
8-Bromo-7-(2-butyn-1-yl)-3-methylxanthine >
1H-Purine-2,6-dione, 8-bromo-7-(2-butyn-1-yl)-3,7-dihydro-3-methyl-
8-Bromo-7-(2-butyn-1-yl)-3,7-dihydro-3-methyl-1H-purine-2,6-dione
LINAGLIPTIN CAS 668270-12-0 INTERMEDIATES
8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione USP/EP/BP
(2-(chloromethyl)-4-methylquinazoline),8-bromo-7-(but-2-ynyl)-3-methyl-1H- purine-2,6(3H,7H)-dione
Linagliptin intermediates,8-bromo-7-(but-2-ynyl)-3-methyl-1H- purine-2,6(3H,7H)-dione
Linagliptin Impurity 73
8-Bromo-7-(but-2-yn-1-yl)-3-methyl-1Hpurin-2,6(3H,7H)-dione
8-bromo-7-but-2-yn-1-yl-3-methyl-3,7-dihydro-1H-purine-2,6-d...
8-Bromo-7-(2-butyn-1-yl)-3-methylxanthine]Q: What is
8-Bromo-7-(2-butyn-1-yl)-3-methylxanthine] Q: What is the CAS Number of
8-Bromo-7-(2-butyn-1-yl)-3-methylxanthine] Q: What is the storage condition of
8-Bromo-7-(2-butyn-1-yl)-3-methylxanthine]
8-BROMO-3-METHYL-7-BUT-2-YNYL XANTHINE
8-Bromo-7-(2-butynyl)-3,7-dihydro-3-methyl-1H-purine-2,6-dione
8-broMo-7-(but-2-yn-1-yl)-3-Methyl-1H-purine-2,6(3H,7H)-dione
8-Bromo-7-(2-butyn-1-yl)-3-methylxanthine
3-Methyl-7-(2-butyn-1-yl)-8-bromoxanthine 8-Bromo-7-(2-butynyl)-3,7-dihydro-3-methyl-1H-purine-2,6-dione
8-Bromo-7-But-2-Ynyl-3-Methyl-Purine-2,6-Dione / Linagliptin Intermediate
Hydrazinecarbothioamide,N-(10-methoxyphenyl)-
8-bromo-7 -(2-butynyl) -3-methylxanthine
8-bromo-3-methyl-7-(prop-1-yn-1-yl)-1H-purine-2,6(3H,7H)-dione
8-Bromo-7-(but-2-yn-1-yl)-3-methyl-1H-purine-2,6(3
Linagliptin intermediate 8-bromo-7-but-2-yn-1-yl-3-methyl-3,7-dihydro-1H-purine-2,6-dione
8-Bromo-7-(2-butynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione
666816-98-4
666816-98-4