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8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione

8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione structure

CAS No.: 666816-98-4

Chemical Name:: 8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione

Synonyms: 8-Bromo-7-(2-butyn-1-yl)-3-methylxanthine;8-broMo-7-(but-2-yn-1-yl)-3-Methyl-1H-purine-2,6(3H,7H)-dione;8-Bromo-7-(2-butynyl)-3,7-dihydro-3-methyl-1H-purine-2,6-dione;3-Methyl-7-(2-butyn-1-yl)-8-bromoxanthine 8-Bromo-7-(2-butynyl)-3,7-dihydro-3-methyl-1H-purine-2,6-dione;Linagliptin INT1;8-BROMO-7-(BUT-2-YNYL);Linagliptin Impurity 36;Linagliptin Impurity 73;Iinagliptin Intermediate2;Linagliptin interMediateC

CBNumber:: CB22538943

Molecular Formula:: C10H9BrN4O2

Molecular Weight:: 297.11

MDL Number:: MFCD22126091

MOL File:: 666816-98-4.mol

Last updated:2024-11-13 21:11:14

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8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione Properties

Melting point	285 °C
Density	1.71
storage temp.	2-8°C
solubility	DMSO (Slightly), Methanol (Slightly)
form	powder to crystal
pka	8.91±0.70(Predicted)
color	White to Almost white
LogP	1.25 at 20℃
CAS DataBase Reference	666816-98-4

SAFETY

Risk and Safety Statements

Hazard statements	H412
Precautionary statements	P273-P501
HS Code	2933.99.8290

8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione price More Price(20)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	B4454	8-Bromo-7-(2-butyn-1-yl)-3-methylxanthine >98.0%(HPLC)(T)	666816-98-4	200mg	$103	2024-03-01	Buy
TCI Chemical	B4454	8-Bromo-7-(2-butyn-1-yl)-3-methylxanthine >98.0%(HPLC)(T)	666816-98-4	1g	$334	2023-01-07	Buy
TRC	B687605	8-Bromo-3-methyl-7-(2-butynyl)-xanthine	666816-98-4	100mg	$65	2021-12-16	Buy
Chem-Impex	43531	8-Bromo-7-(2-butyn-1-yl)-3-methylxanthine,≥98%(HPLC) ≥98%(HPLC)	666816-98-4	200MG	$107.46	2021-12-16	Buy
Matrix Scientific	096910	8-Bromo-7-(but-2-yn-1-yl)-3-methyl-1H-purine-2,6(3H,7H)-dione 95+%	666816-98-4	1g	$19	2021-12-16	Buy

Product number	Packaging	Price	Buy
B4454	200mg	$103	Buy
B4454	1g	$334	Buy
B687605	100mg	$65	Buy
43531	200MG	$107.46	Buy
096910	1g	$19	Buy

8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione Chemical Properties,Uses,Production

Chemical Properties

White powder

Synthesis

8-bromo-3-methyl-3,7-dihydro-1H-purine-2,6-dione (2.450 g, 10 mmol),1-bromo-2-butyne (1.596 g, 12 mmol), Sodium carbonate (1.590 g, 15 mmol), and 20mL of acetone was added to a 100mL flask. The reaction system was heated to 40 ° C, and the reaction was stirred for 4h. After the reaction was cooled to room temperature, suction filtration was performed, and the filter cake was washed with methanol to obtain a crude product as a pale yellow solid. The crude product was reconstituted with dichloromethane and cyclohexane. Yield 2.912 g of 8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione. The yield was 98%, and the purity was 99.9%.

8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione synthesis

Synthesis of 8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione from 8-Bromo-3-methyl-xanthine and 1-BROMO-2-BUTYNE

8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione Preparation Products And Raw materials

Raw materials

8-Bromo-3-methyl-xanthine 1-BROMO-2-BUTYNE

Preparation Products

8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione Suppliers

Global( 417)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Joiny Pharmaceutical Co.,LTD	+8613681955282	gyd@joiny-pharma.com	China	255	58
Sinoway Industrial co., ltd.	0592-5800732; +8613806035118	xie@china-sinoway.com	China	988	58
Anhui Ruihan Technology Co., Ltd	+8617756083858	daisy@anhuiruihan.com	China	973	58
Frapp's ChemicalNFTZ Co., Ltd.	+86 (576) 8169-6106	sales@frappschem.com	China	880	50
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29791	60
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1803	55
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21634	55
Hangzhou FandaChem Co.,Ltd.	+8615858145714	FandaChem@Gmail.com	China	9206	55
Shanghai Yingrui Biopharma Co., Ltd.	+86-21-33585366 - 03@	sales03@shyrchem.com	CHINA	738	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32957	60

Supplier	Advantage
Shanghai Joiny Pharmaceutical Co.,LTD	58
Sinoway Industrial co., ltd.	58
Anhui Ruihan Technology Co., Ltd	58
Frapp's ChemicalNFTZ Co., Ltd.	50
Capot Chemical Co.,Ltd.	60
Beijing Cooperate Pharmaceutical Co.,Ltd	55
Henan Tianfu Chemical Co.,Ltd.	55
Hangzhou FandaChem Co.,Ltd.	55
Shanghai Yingrui Biopharma Co., Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60

View Lastest Price from 8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-11-29	8-Bromo-7-But-2-Ynyl-3-Methyl-Purine-2,6-Dione / Linagliptin Intermediate 666816-98-4	US $0.00-0.00 / kg	1kg	99%	20tons	Sinoway Industrial co., ltd.
2024-11-26	8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione 666816-98-4	US $0.00-0.00 / kg	1kg	98%	1 ton	Nanjing Fred Technology Co., Ltd
2024-11-18	8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione 666816-98-4	US $0.00-0.00 / KG	1KG	98.0%	10000KGS	Shaanxi Dideu New Materials Co. Ltd

8-Bromo-7-But-2-Ynyl-3-Methyl-Purine-2,6-Dione / Linagliptin Intermediate
666816-98-4
US $0.00-0.00 / kg
99%
Sinoway Industrial co., ltd.

8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione
666816-98-4
US $0.00-0.00 / kg
98%
Nanjing Fred Technology Co., Ltd

8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione
666816-98-4
US $0.00-0.00 / KG
98.0%
Shaanxi Dideu New Materials Co. Ltd

666816-98-4(8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione)Related Search:

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Rivaroxaban 3-(R)-Piperidinyl PhthaliMide D-(-)-tartaric acid Linagliptin 5-Acetyl Rhein 1,1'-[(5E)-5-Methyl-7-oxo-5-undecene-1,11-diyl] Bis

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8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione 8-broMo-7-(but-2-ynyl)-3-Methyl-3,7-dihydropurine-2,6-dione 3-Methyl-7-(2-butyn-1-yl)-8-bromoxanthine 8-broMo-7-but-2-yn-1-yl-3-Methyl-3,7-dihydro-1H-purine-2,6-dione 8-BroMo-7-(2-butyn-a-yl)-3,7-dihydro-3-Methyl-1-1H-purine-2,6-dione Linagliptin interMediateC (R)-tert-butyl 1-(7-(but-2-ynyl)-3-Methyl-1-((4-Methylquinazolin-2-yl)Methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-ylcarbaMate 3-Methyl-7-(2-butin-1-yl)-8-broMoxanthine 1H-Purine-2,6-dione, 8-broMo-7-(2-butynyl)-3,7-dihydro-3-Methyl- Iinagliptin Intermediate2 Linagliptin INT1 8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione/3-Methyl-7-(2-butyn-1-yl)-8-bromoxanthine 8-Bromo-7-(2- butynyl)-3,7-dihydro- 3-methyl-1H-pur ine-2,6-dion 8-BROMO-7-(BUT-2-YNYL) 8-bromo-7-(but-2-ynyl)-3-methyl-3,4,5,7-tetrahydro-1H-purine-2,6-dione 8-Bromo-7-(but-2-yn-1-yl)-3-methyl-1H-purine-2,6(3H 8- bromo -7-(2- butyne)-3- methyl xanthine 8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2 8-bromo-7-(2-butynyl)-3,7-dihydro-3-methyl-1H-indole-2,6-dione Linagliptin Impurity 36 8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dion 8-Bromo-7-(2-butyn-1-yl)-3-methylxanthine > 1H-Purine-2,6-dione, 8-bromo-7-(2-butyn-1-yl)-3,7-dihydro-3-methyl- 8-Bromo-7-(2-butyn-1-yl)-3,7-dihydro-3-methyl-1H-purine-2,6-dione LINAGLIPTIN CAS 668270-12-0 INTERMEDIATES 8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione USP/EP/BP (2-(chloromethyl)-4-methylquinazoline)，8-bromo-7-(but-2-ynyl)-3-methyl-1H- purine-2,6(3H,7H)-dione Linagliptin intermediates，8-bromo-7-(but-2-ynyl)-3-methyl-1H- purine-2,6(3H,7H)-dione Linagliptin Impurity 73 8-Bromo-7-(but-2-yn-1-yl)-3-methyl-1Hpurin-2,6(3H,7H)-dione 8-bromo-7-but-2-yn-1-yl-3-methyl-3,7-dihydro-1H-purine-2,6-d... 8-Bromo-7-(2-butyn-1-yl)-3-methylxanthine]Q: What is 8-Bromo-7-(2-butyn-1-yl)-3-methylxanthine] Q: What is the CAS Number of 8-Bromo-7-(2-butyn-1-yl)-3-methylxanthine] Q: What is the storage condition of 8-Bromo-7-(2-butyn-1-yl)-3-methylxanthine] 8-BROMO-3-METHYL-7-BUT-2-YNYL XANTHINE 8-Bromo-7-(2-butynyl)-3,7-dihydro-3-methyl-1H-purine-2,6-dione 8-broMo-7-(but-2-yn-1-yl)-3-Methyl-1H-purine-2,6(3H,7H)-dione 8-Bromo-7-(2-butyn-1-yl)-3-methylxanthine 3-Methyl-7-(2-butyn-1-yl)-8-bromoxanthine 8-Bromo-7-(2-butynyl)-3,7-dihydro-3-methyl-1H-purine-2,6-dione 8-Bromo-7-But-2-Ynyl-3-Methyl-Purine-2,6-Dione / Linagliptin Intermediate Hydrazinecarbothioamide,N-(10-methoxyphenyl)- 8-bromo-7 -(2-butynyl) -3-methylxanthine 8-bromo-3-methyl-7-(prop-1-yn-1-yl)-1H-purine-2,6(3H,7H)-dione 8-Bromo-7-(but-2-yn-1-yl)-3-methyl-1H-purine-2,6(3 Linagliptin intermediate 8-bromo-7-but-2-yn-1-yl-3-methyl-3,7-dihydro-1H-purine-2,6-dione 8-Bromo-7-(2-butynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione 8-BROMO-7-(BUT-2-YN-1-YL)-3-METHYL-1H-PURINE-2,6-DIONE 8-Bromo-7-but-2-ynyl-3-methyl-4,5-dihydropurine-2,6-dione 666816-98-4 666816-98-4