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N-Octadecyl-N'-propyl-sulfamide

CAS No.
925891-74-3
Chemical Name:
N-Octadecyl-N'-propyl-sulfamide
Synonyms
N-Octadecyl-N'-propyl-sulfamide;Sulfamide, N-octadecyl-N'-propyl-;N-(propylsulfamoyl)octadecan-1-amine
CBNumber:
CB22591861
Molecular Formula:
C21H46N2O2S
Molecular Weight:
390.67
MDL Number:
MFCD10565622
MOL File:
925891-74-3.mol
Last updated:2023-05-21 10:59:17

N-Octadecyl-N'-propyl-sulfamide Properties

storage temp. Store at -20°C
solubility ≤0.2mg/ml in ethanol
form crystalline solid

N-Octadecyl-N'-propyl-sulfamide price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 10009661 N-Octadecyl-N'-propyl-sulfamide ≥95% 925891-74-3 5mg $76 2024-03-01 Buy
Cayman Chemical 10009661 N-Octadecyl-N'-propyl-sulfamide ≥95% 925891-74-3 10mg $142 2024-03-01 Buy
Cayman Chemical 10009661 N-Octadecyl-N'-propyl-sulfamide ≥95% 925891-74-3 25mg $335 2024-03-01 Buy
Cayman Chemical 10009661 N-Octadecyl-N'-propyl-sulfamide ≥95% 925891-74-3 50mg $593 2024-03-01 Buy
ApexBio Technology C4735 N-Octadecyl-N'-propyl-sulfamide 925891-74-3 25mg $381 2021-12-16 Buy
Product number Packaging Price Buy
10009661 5mg $76 Buy
10009661 10mg $142 Buy
10009661 25mg $335 Buy
10009661 50mg $593 Buy
C4735 25mg $381 Buy

N-Octadecyl-N'-propyl-sulfamide Chemical Properties,Uses,Production

Description

Peroxisome proliferator-activated receptors (PPARs) play an essential role in regulating lipid and glucose metabolism. Oleoyl ethanolamide (OEA), a natural ligand for PPARα, has been shown to suppress food intake and reduce weight gain in rats when administered systemically at 10 mg/kg intraperitoneally. N-Octadecyl-N''-propyl-sulfamide is an analog of OEA with selective binding affinity for PPARα. It is a more potent activator of PPARα, exhibiting an EC50 value of 100 nM, compared to OEA, which exhibits an EC50 value of 120 nM. At a dose of 1 mg/kg for 8-11 days, N-octadecyl-N''-propyl-sulfamide induces satiety, thereby decreasing food-intake, body weight, and plasma triglyceride concentration in free-feeding Wistar and obese Zucker (fa/fa) rats.

References

[1]. cano c, pavón j, serrano a, et al. novel sulfamide analogs of oleoylethanolamide showing in vivo satiety inducing actions and pparalpha activation. j med chem. 2007 jan 25;50(2):389-93.
[2]. fu j1, gaetani s, oveisi f, et al. oleylethanolamide regulates feeding and body weight through activation of the nuclear receptor ppar-alpha. nature. 2003 sep 4;425(6953):90-3.

N-Octadecyl-N'-propyl-sulfamide Preparation Products And Raw materials

Raw materials

Preparation Products

N-Octadecyl-N'-propyl-sulfamide Suppliers

Global( 19)Suppliers
Supplier Tel Email Country ProdList Advantage
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8141 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8739 58
ApexBio Technology -- sales@apexbt.com United States 6254 58
N-Octadecyl-N'-propyl-sulfamide N-(propylsulfamoyl)octadecan-1-amine Sulfamide, N-octadecyl-N'-propyl- 925891-74-3 C21H46N2O2S