ChemicalBook >> CAS DataBase List >>ABT 894
ABT 894
- CAS No.
- 799279-80-4
- Chemical Name:
- ABT 894
- Synonyms
- ABT 894;Sofiniclin;A 422894.0;Sofinicline;ABT-894; ABT 894; ABT894;3,6-Diazabicyclo[3.2.0]heptane, 3-(5,6-dichloro-3-pyridinyl)-, (1S,5S)-
- CBNumber:
- CB22627245
- Molecular Formula:
- C10H11Cl2N3
- Molecular Weight:
- 244.12
- MDL Number:
- MFCD19443714
- MOL File:
- 799279-80-4.mol
- MSDS File:
- SDS
Last updated:2024-07-02 08:55:03
| Boiling point | 417.4±45.0 °C(Predicted) |
|---|---|
| Density | 1.406±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | Soluble in DMSO |
| form | Solid |
| pka | 10.31±0.20(Predicted) |
| color | Off-white to brown |
| FDA UNII | SQC232V4YY |
ABT 894 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| American Custom Chemicals Corporation | KIN0001099 | ABT-894 95.00% | 799279-80-4 | 1G | $186.9 | 2021-12-16 | Buy |
| ChemScene | CS-6792 | Sofiniclin 95.98% | 799279-80-4 | 1mg | $432 | 2021-12-16 | Buy |
| ChemScene | CS-6792 | Sofiniclin 95.98% | 799279-80-4 | 5mg | $864 | 2021-12-16 | Buy |
| ChemScene | CS-6792 | Sofiniclin 95.98% | 799279-80-4 | 10mg | $1596 | 2021-12-16 | Buy |
ABT 894 Chemical Properties,Uses,Production
Biological Activity
Sofiniclin (ABT 894) is an agonist of nAChR as a potential non-stimulatory study in attention deficit disorder.
in vitro
ABT 894 is more potent than ABT-089 at both receptor subtypes, with K i values of 1.9 nM for 125 I-α-conotoxinMII binding and of 1.3 nM for 125 I-epibatidine binding.
in vivo
ABT 894 (0.001 to 0.10 mg/kg, po) produces significant reductions in LIDs compared to vehicle monkey. It does not decrease LIDs in monkeys with severe nigrostriatal damage.
< p>ABT 894 Preparation Products And Raw materials
Raw materials
Preparation Products
ABT 894 Suppliers
Global( 16)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | sales@chemhifuture.com | China | 3136 | 58 |
| MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4863 | 58 |
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9730 | 58 |
| BOC Sciences | -- | info@bocsci.com | USA | 0 | 65 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Absin Bioscience Inc. | 021-38015121 15000105423 | chenjw@absin.cn | China | 24734 | 58 |
| Nantong Hi-Future Biotechnology Co., Ltd | 18051384581 | sales@chemhifuture.com | China | 3059 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 | psaitong@jm-bio.com | China | 29778 | 58 |
ABT 894
A 422894.0
Sofiniclin
Sofinicline
ABT-894; ABT 894; ABT894
3,6-Diazabicyclo[3.2.0]heptane, 3-(5,6-dichloro-3-pyridinyl)-, (1S,5S)-
799279-80-4