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D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT

CAS No.
103404-90-6
Chemical Name:
D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT
Synonyms
d-α-hydroxyglutaric acid disodium salt;sodiuM 2-hydroxypentanedioate;(r)-2-hydroxypentanedioic acid;Disodium (R)-2-hydroxyglutarate;(2R)-2-Hydroxypentanedioic acid;D-A-HYDROXYGLUTARIC ACID DISODIUM;SodiuM (R)-2-hydroxypentanedioate;D-α-Hydroxyglutaric acid disodium;isodium,(2R)-2-hydroxypentanedioate;D-α-Hydroxyglutaricaciddisodiumsalt
CBNumber:
CB2266017
Molecular Formula:
C5H9NaO5
Molecular Weight:
172.11
MDL Number:
MFCD00069573
MOL File:
103404-90-6.mol
MSDS File:
SDS
Last updated:2024-11-19 15:53:33

D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT Properties

Melting point >291°C (dec.)
storage temp. -20°C
solubility PBS (pH 7.2): 10 mg/ml
form A crystalline solid
color White to light yellow
optical activity [α]/D 8.5±1.5°, c = 1 in NaOH
Water Solubility Soluble to 100 mM in water
BRN 5318041
Stability Hygroscopic
InChIKey DZHFTEDSQFPDPP-HWYNEVGZSA-L

SAFETY

Risk and Safety Statements

WGK Germany  3
HS Code  29181990

D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT price More Price(42)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 16859 D-α-Hydroxyglutaric acid disodium salt ≥98.0% (GC) 103404-90-6 10mg $78.6 2024-03-01 Buy
Sigma-Aldrich 16859 D-α-Hydroxyglutaric acid disodium salt ≥98.0% (GC) 103404-90-6 50mg $316 2024-03-01 Buy
Cayman Chemical 11605 D-α-Hydroxyglutaric Acid (sodium salt) ≥95% 103404-90-6 10mg $49 2024-03-01 Buy
Cayman Chemical 11605 D-α-Hydroxyglutaric Acid (sodium salt) ≥95% 103404-90-6 25mg $109 2024-03-01 Buy
Sigma-Aldrich H8378 D-α-Hydroxyglutaric acid disodium salt ≥95% (GC) 103404-90-6 100mg $519 2024-03-01 Buy
Product number Packaging Price Buy
16859 10mg $78.6 Buy
16859 50mg $316 Buy
11605 10mg $49 Buy
11605 25mg $109 Buy
H8378 100mg $519 Buy

D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT Chemical Properties,Uses,Production

Description

D-α-Hydroxyglutaric Acid (D-2-HG) is an α-hydroxy acid that is over-produced in the human neurometabolic disease D-2-hydroxyglutaric aciduria (D-2-HGA). It is normally synthesized from 2-ketoglutarate (2-KG) by hydroxyacid-oxoacid transhydrogenase (HOT), although defects in HOT are not known to be associated with D-2-HGA. Instead, type I D-2-HGA involves mutations in D-2-hydroxyglutarate dehydrogenase, which converts D-2-HG back to 2-KG. Type II D-2-HGA results from gain-of-function mutations in isocitrate dehydrogenase 2, causing it to supplement HOT in converting 2-KG to D-2-HG. In bacteria, this α-hydroxy acid may be synthesized from oxalate and propionyl-coenzyme A by an α-hydroxyglutaric acid synthetase.

Chemical Properties

Pale Orange Solid

Uses

A potential inhibitor of glutamate carboxypeptidase.

Biochem/physiol Actions

Biomarker for inborn errors of metabolism and cancer

storage

Store at -20°C

D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 138)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32957 60
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29881 58
Hubei xin bonus chemical co. LTD
86-13657291602 linda@hubeijusheng.com CHINA 22963 58
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19553 58
Chongqing Chemdad Co., Ltd
+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39894 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49374 58
Zhengzhou Alfa Chemical Co.,Ltd
+8618530059196 sale04@alfachem.cn China 13432 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32165 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6312 58

View Lastest Price from D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
D-α-Hydroxyglutaric acid disodium pictures 2024-11-19 D-α-Hydroxyglutaric acid disodium
103404-90-6
US $30.00-67.00 / mg 98% 10g TargetMol Chemicals Inc.
D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT pictures 2019-08-02 D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT
103404-90-6
US $1.00 / KG 1KG 95-99% 500kg/month Career Henan Chemical Co

D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT Spectrum

D-alpha-Hydroxyglutaric acid disodiuM salt >=95% (GC) Disodium (R)-2-hydroxyglutarate D-α-Hydroxyglutaric Acid (sodium salt) D-ALPHA-HYDROXYGLUTARIC ACID DISODIU D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT D-ALPHA-HYDROXYGLUTARIC ACID DISODIUM SALT D-A-HYDROXYGLUTARIC ACID DISODIUM (r)-2-hydroxypentanedioic acid (2R)-2-Hydroxyglutaric Acid Disodium Salt Pentanedioic acid,2-hydroxy-, disodium salt, (2R)- sodiuM 2-hydroxypentanedioate SodiuM (R)-2-hydroxypentanedioate D-α-Hydroxyglutaric acid disodiuM salt D-α-Hydroxypentanedioic acid disodium salt, 95% D-.alpha.-Hydroxyglutaric Acid (sodium salt) D-alpha-Hydroxyglutaric Acid Disodium disodium:(2R)-2-hydroxypentanedioate (2R)-2-Hydroxypentanedioic acid isodium,(2R)-2-hydroxypentanedioate D-α-Hydroxyglutaric acid disodium D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT USP/EP/BP d-α-hydroxyglutaric acid disodium salt D-α-Hydroxyglutaricaciddisodiumsalt D-3-Hydroxypentanedioic acid disodium salt Pentanedioic acid, 2-hydroxy-, sodium salt (1:2), (2R)- (2R)-2-hydroxy-Pentanedioic acid sodium salt (1:2) D-α-Hydroxyglutaric Acid (sodium salt) Pentanedioic acid,2-hydroxy-,disodium salt,(2R)-(9ci) 103404-90-6 C5H6Na2O5 Peptide Synthesis Specialty Synthesis Amino Acid Derivatives Aliphatics Chiral Reagents Inhibitors