D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT
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D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT 속성
- 녹는점
- >291°C (dec.)
- 저장 조건
- -20°C
- 용해도
- PBS (pH 7.2): 10 mg/ml
- 물리적 상태
- 결정성 고체
- 색상
- White to light yellow
- optical activity
- [α]/D 8.5±1.5°, c = 1 in NaOH
- 수용성
- 물에 100mM까지 용해됨
- BRN
- 5318041
- 안정성
- 흡습성
- InChIKey
- DZHFTEDSQFPDPP-HWYNEVGZSA-L
안전
WGK 독일 | 3 | ||
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HS 번호 | 29181990 |
D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT C화학적 특성, 용도, 생산
개요
D-α-Hydroxyglutaric Acid (D-2-HG) is an α-hydroxy acid that is over-produced in the human neurometabolic disease D-2-hydroxyglutaric aciduria (D-2-HGA). It is normally synthesized from 2-ketoglutarate (2-KG) by hydroxyacid-oxoacid transhydrogenase (HOT), although defects in HOT are not known to be associated with D-2-HGA. Instead, type I D-2-HGA involves mutations in D-2-hydroxyglutarate dehydrogenase, which converts D-2-HG back to 2-KG. Type II D-2-HGA results from gain-of-function mutations in isocitrate dehydrogenase 2, causing it to supplement HOT in converting 2-KG to D-2-HG. In bacteria, this α-hydroxy acid may be synthesized from oxalate and propionyl-coenzyme A by an α-hydroxyglutaric acid synthetase.화학적 성질
Pale Orange Solid용도
A potential inhibitor of glutamate carboxypeptidase.D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT 준비 용품 및 원자재
원자재
준비 용품
D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT 공급 업체
글로벌( 135)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32760 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29894 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22968 | 58 |
BOC Sciences | +1-631-485-4226 |
inquiry@bocsci.com | United States | 19553 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 |
sales@chemdad.com | China | 39916 | 58 |
Alchem Pharmtech,Inc. | 8485655694 |
sales@alchempharmtech.com | United States | 63711 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49391 | 58 |
Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 |
sale04@alfachem.cn | China | 13214 | 58 |
HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 |
sales@hzclap.com | CHINA | 6313 | 58 |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 |
1026@dideu.com | China | 24330 | 58 |