D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT
- CAS No.
- 103404-90-6
- Chemical Name:
- D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT
- Synonyms
- d-α-hydroxyglutaric acid disodium salt;sodiuM 2-hydroxypentanedioate;(r)-2-hydroxypentanedioic acid;Disodium (R)-2-hydroxyglutarate;(2R)-2-Hydroxypentanedioic acid;D-A-HYDROXYGLUTARIC ACID DISODIUM;SodiuM (R)-2-hydroxypentanedioate;D-α-Hydroxyglutaric acid disodium;isodium,(2R)-2-hydroxypentanedioate;D-α-Hydroxyglutaricaciddisodiumsalt
- CBNumber:
- CB2266017
- Molecular Formula:
- C5H9NaO5
- Molecular Weight:
- 172.11
- MDL Number:
- MFCD00069573
- MOL File:
- 103404-90-6.mol
- MSDS File:
- SDS
Melting point | >291°C (dec.) |
---|---|
storage temp. | -20°C |
solubility | PBS (pH 7.2): 10 mg/ml |
form | A crystalline solid |
color | White to light yellow |
optical activity | [α]/D 8.5±1.5°, c = 1 in NaOH |
Water Solubility | Soluble to 100 mM in water |
BRN | 5318041 |
Stability | Hygroscopic |
InChIKey | DZHFTEDSQFPDPP-HWYNEVGZSA-L |
D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT price More Price(42)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 16859 | D-α-Hydroxyglutaric acid disodium salt ≥98.0% (GC) | 103404-90-6 | 10mg | $78.6 | 2024-03-01 | Buy |
Sigma-Aldrich | 16859 | D-α-Hydroxyglutaric acid disodium salt ≥98.0% (GC) | 103404-90-6 | 50mg | $316 | 2024-03-01 | Buy |
Cayman Chemical | 11605 | D-α-Hydroxyglutaric Acid (sodium salt) ≥95% | 103404-90-6 | 10mg | $49 | 2024-03-01 | Buy |
Cayman Chemical | 11605 | D-α-Hydroxyglutaric Acid (sodium salt) ≥95% | 103404-90-6 | 25mg | $109 | 2024-03-01 | Buy |
Sigma-Aldrich | H8378 | D-α-Hydroxyglutaric acid disodium salt ≥95% (GC) | 103404-90-6 | 100mg | $519 | 2024-03-01 | Buy |
D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT Chemical Properties,Uses,Production
Description
D-α-Hydroxyglutaric Acid (D-2-HG) is an α-hydroxy acid that is over-produced in the human neurometabolic disease D-2-hydroxyglutaric aciduria (D-2-HGA). It is normally synthesized from 2-ketoglutarate (2-KG) by hydroxyacid-oxoacid transhydrogenase (HOT), although defects in HOT are not known to be associated with D-2-HGA. Instead, type I D-2-HGA involves mutations in D-2-hydroxyglutarate dehydrogenase, which converts D-2-HG back to 2-KG. Type II D-2-HGA results from gain-of-function mutations in isocitrate dehydrogenase 2, causing it to supplement HOT in converting 2-KG to D-2-HG. In bacteria, this α-hydroxy acid may be synthesized from oxalate and propionyl-coenzyme A by an α-hydroxyglutaric acid synthetase.
Chemical Properties
Pale Orange Solid
Uses
A potential inhibitor of glutamate carboxypeptidase.
Biochem/physiol Actions
Biomarker for inborn errors of metabolism and cancer
storage
Store at -20°C
D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32957 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29881 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49374 | 58 |
Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 13432 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32165 | 58 |
HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6312 | 58 |
View Lastest Price from D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-11-19 | D-α-Hydroxyglutaric acid disodium
103404-90-6
|
US $30.00-67.00 / mg | 98% | 10g | TargetMol Chemicals Inc. | |||
2019-08-02 | D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT
103404-90-6
|
US $1.00 / KG | 1KG | 95-99% | 500kg/month | Career Henan Chemical Co |
- D-α-Hydroxyglutaric acid disodium
103404-90-6
- US $30.00-67.00 / mg
- 98%
- TargetMol Chemicals Inc.
- D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT
103404-90-6
- US $1.00 / KG
- 95-99%
- Career Henan Chemical Co