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Pymetrozine

Pymetrozine structure

CAS No.: 123312-89-0

Chemical Name:: Pymetrozine

Synonyms: PYMETROZIN;6-Methyl-4-((pyridin-3-ylMethylene)aMino)-4,5-dihydro-1,2,4-triazin-3(2H)-one;CHESS;PLENUM;A 9364A;Fulfill;Endeavor;Hsdb 7054;pyrhexone;Cga 215944

CBNumber:: CB2267731

Molecular Formula:: C10H11N5O

Molecular Weight:: 217.23

MDL Number:: MFCD01632346

MOL File:: 123312-89-0.mol

Last updated:2025-01-27 09:38:02

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Pymetrozine Properties

Melting point	234.4°
Density	1.36g/cm3 (20～25℃）
vapor pressure	0Pa at 25.03℃
Flash point	>230 °C
storage temp.	0-6°C
solubility	DMSO (Slightly), Methanol (Slightly)
pka	12.90±0.40(Predicted)
form	Solid
color	White to Light Beige
BRN	7814151
Stability	Hygroscopic
InChIKey	QHMTXANCGGJZRX-WUXMJOGZSA-N
LogP	-0.18 at 25℃ and pH7.1
Surface tension	69.4-72.3mN/m at 10g/L and 20℃
Dissociation constant	0.19-4.07 at 20℃
CAS DataBase Reference	123312-89-0(CAS DataBase Reference)
EWG's Food Scores	2
FDA UNII	F0G3V7874J
Proposition 65 List	Pymetrozine
EPA Substance Registry System	Pymetrozine (123312-89-0)
UNSPSC Code	41116107
NACRES	NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS08,GHS09
Signal word	Warning
Hazard statements	H351-H361fd-H410
Precautionary statements	P202-P273-P280-P308+P313-P391-P405
Hazard Codes	Xn
Risk Statements	40-52/53-R52/53-R40
Safety Statements	36/37-61-S61-S36/37
WGK Germany	2
RTECS	XZ3018620
HS Code	29336990
Hazardous Substances Data	123312-89-0(Hazardous Substances Data)
Toxicity	LD50 orally in rats: 5820 mg/kg (Flückiger)

Pymetrozine price More Price(8)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	46119	Pymetrozin PESTANAL?, analytical standard	123312-89-0	250mg	$106	2024-03-01	Buy
TRC	P840350	Pymetrozine	123312-89-0	10g	$1030	2021-12-16	Buy
Medical Isotopes, Inc.	42131	Pymetrozine	123312-89-0	10g	$2000	2021-12-16	Buy
American Custom Chemicals Corporation	PST0000165	PYMETROZINE 95.00%	123312-89-0	10G	$2194.5	2021-12-16	Buy
AK Scientific	P699	Pymetrozine	123312-89-0	250mg	$131	2021-12-16	Buy

Product number	Packaging	Price	Buy
46119	250mg	$106	Buy
P840350	10g	$1030	Buy
42131	10g	$2000	Buy
PST0000165	10G	$2194.5	Buy
P699	250mg	$131	Buy

Pymetrozine Chemical Properties,Uses,Production

Descriptioin

Pymetrozine is a new neuroactive insecticide. It has a remarkable selectivity for sucking insect pests, such as aphids, whiteflies, and plant hoppers, due to its systemic action. Pymetrozine is the only representative of the pyridine azomethines, a new class of insecticides. Pymetrozine has been determined to be of low acute toxicity to humans, birds, aquatic organisms, mammals, and bees. It is also not mutagenic.

Reference

[1] J. Ausborn, H. Wolf, W. Mader, H. Kayser, The insecticide pymetrozine selectively against affects chordotonal mechanoreceptors, Journal of Experimental Biology, 2005, vol. 208, pp. 4451-4466.
[2] D. Fuog, S. J. Fergusson, C. Flückiger, Pymetrozine: A Novel Insecticide Affecting Aphids and Whiteflies, Insecticides with Novel Modes of Action, 1998, ISBN 978-3-642-08314-3
[3] Yu, Jixin et al. “Acute Toxicity of an Emerging Insecticide Pymetrozine to Procambarus clarkii Associated with Rice-Crayfish Culture (RCIS).” International journal of environmental research and public health vol. 15,5 984. 14 May. 2018, doi:10.3390/ijerph15050984

Uses

Pymetrozine is a pyridine azomethine antifeedant. Pymetrozine is used as insecticide.

Definition

ChEBI: A member of the class of 1,2,4-triazines that is 4,5-dihydro-1,2,4-triazin-3(2H)-one substituted by a methyl group at position 6 and a (pyridin-3-ylmethylidene)amino group at position 4.

Mode of action

Pymetrozine, 6-methyl-4-[(E)-(pyridin-3-ylmethylene) amino]-4,5-dihydro-2H-[1-3]-triazin-3 one, is a pyridine azomethine compound, which represents an emerging insecticide for plant-sucking insects, such as aphids, whiteflies and plant hoppers. In addition, pymetrozine has been reported to have effects on neuro regulation or nerve-muscle interaction in sucking insects, thus preventing the insertion of their style into the plant tissue. It has been widely applied on rice and other crops in China as a substitute for organophosphorus pesticides since approximately 2006 and is rated as a Class 1 pesticide (i.e., harmless according to the International Organization for Biological and Integrated Control Scale). Pymetrozine affects the behaviour of homopterous insects and causes them to stop feeding, eventually leading to their death[3].

Pymetrozine synthesis

Synthesis of Pymetrozine from 3-Pyridinecarboxaldehyde and 1,2,4-Triazin-3(2H)-one, 4-amino-4,5-dihydro-6-methyl-

Pymetrozine Preparation Products And Raw materials

Raw materials

1,2,4-Triazin-3(2H)-one, 4-amino-4,5-dihydro-6-methyl-

Preparation Products

Pymetrozine Suppliers

Global( 288)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
NANJING ACE CHEMICAL CO.,LTD	+8618268053070	e.wen@ace-chemical.com	China	7	58
Shijiazhuang Tongyang Import and Export Co., LTD	18031361688;	admin@sjztongyang.com	China	977	58
AS WATER CO., LTD.	+86-18994963526 +8618994963526	1346073549@qq.com	United Kingdom	176	58
Hebei Weibang Biotechnology Co., Ltd	+8615531157085	abby@weibangbio.com	China	8804	58
Hebei Yanxi Chemical Co., Ltd.	+8617531153977	allison@yan-xi.com	China	5855	58
Qingdao Trust Agri Chemical Co.,Ltd	+8613573296305	aroma@qdtrustagri.com	China	301	58
Hebei Weibang Biotechnology Co., Ltd	+8617732866630	bess@weibangbio.com	China	18147	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21632	55
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	FandaChem@Gmail.com	China	8341	55
Shanxi Naipu Import and Export Co.,Ltd	+86-13734021967 +8613734021967	kaia@neputrading.com	China	1001	58

Supplier	Advantage
NANJING ACE CHEMICAL CO.,LTD	58
Shijiazhuang Tongyang Import and Export Co., LTD	58
AS WATER CO., LTD.	58
Hebei Weibang Biotechnology Co., Ltd	58
Hebei Yanxi Chemical Co., Ltd.	58
Qingdao Trust Agri Chemical Co.,Ltd	58
Hebei Weibang Biotechnology Co., Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
Hangzhou FandaChem Co.,Ltd.	55
Shanxi Naipu Import and Export Co.,Ltd	58

View Lastest Price from Pymetrozine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-02-14	Pymetrozine 123312-89-0	US $0.00 / KG	1KG	99%	5000kg	Hebei Mujin Biotechnology Co.,Ltd
2024-11-26	pymetrozine 123312-89-0	US $0.00 / kg	10kg	50%	200	qingdao trust agri chemical co.,ltd
2024-11-19	Pymetrozine 123312-89-0	US $41.00 / mg		99.56%	10g	TargetMol Chemicals Inc.

Pymetrozine
123312-89-0
US $0.00 / KG
99%
Hebei Mujin Biotechnology Co.,Ltd

pymetrozine
123312-89-0
US $0.00 / kg
50%
qingdao trust agri chemical co.,ltd

Pymetrozine
123312-89-0
US $41.00 / mg
99.56%
TargetMol Chemicals Inc.

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1of4

Hsdb 7054 (E)-4,5-dihydro-6-Methyl-4-[(3-pyridinylMethylene)aMino]-1,2,4-triazin-3(2H)-one 4,5-Dihydro-6-Methyl-4-[(E)-(3-pyridinylMethylene)aMino]-1,2,4-triazin-3(2H)-one A 9364A (E)-6-Methyl-4-((pyridin-3-ylMethylene)aMino)-4,5-dihydro-1,2,4-triazin-3(2H)-one Pymetrozine 0 Pymetrozin Solution, 100ppm CHESS (e)-4,5-fihydro-6-methyl-4-((3-pyridinylmethylene)amino)-1,2,4-triazin-3(2h)-one PLENUM PYMETROZINE pymetrozine (ISO) (E)-4,5-dihydro-6-methyl-4-(3-pyridylmethyleneamino)-1,2,4-triazin-3(2H)-one 1,2,4-Triazin-3(2H)-one, 4,5-dihydro-6-methyl-4-((3-pyridinylmethylene)amino)-, (E)- Cga 215944 Einecs annex I index 613-202-00-4 Endeavor Fulfill 1,2,4-Triazin-3(2H)-one, 4,5-dihydro-6-methyl-4-(E)-(3-pyridinylmethylene)amino- pymetrozine (bsi, pa e-iso) PYMETHROZINE (E)-4,5-Dihydro-6-methyl-4(3-pyridylmethyleneamino)-1,2,4-triazin-3(2H)-one PYMETROZIN PESTANAL, 250 MG 6-Methyl-4-(pyridin-3-ylmethylideneamino)-2,5-dihydro-1,2,4-triazin-3-one Agkistrodon Halys Antivenin-1109 Venom of Agkistrodon Pallas Viper venom 6-methyl-4-[(E)-3-pyridinylmethylideneamino]-2,5-dihydro-1,2,4-triazin-3-one 100 μg/mL in AcCN Pymetrozine Standard 6-Methyl-4-((pyridin-3-ylMethylene)aMino)-4,5-dihydro-1,2,4-triazin-3(2H)-one PYMETROZIN Pyrazole ketone of aphid pyrhexone Pymetrozin Solution in Methanol Pymetrozine TC L16587000MEPymetrozinE10μg/mLin Methanol Pymetrozine 10.0 μg/ml Acetonitrile Pymetrozine in Methanol pymetrozine (ISO) Pymetrozine, 10 mM in DMSO CAS:123312-89-0 123312-89-0 23312-89-0 C10H11N5O C10H11N50 Alpha sort N-PPesticides&Metabolites OthersAlphabetic P Pesticides Pesticides&Metabolites PU - PZ Agro-Products Aromatics Heterocycles 123312-89-0