Buprofezin | 69327-76-0

Buprofezin Properties

Melting point	104-106°C
alpha	22 º (c=8,6N HCl)
Boiling point	273°C (12 torr)
Density	1.18
vapor pressure	1.25 x l0^-3 Pa (25 °C)
refractive index	1.52-1.522
Flash point	176-178°C
storage temp.	0-6°C
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Solid
pka	3.02±0.20(Predicted)
color	White to Pale Beige
Water Solubility	0.9 mg/L at 20 ºC
Decomposition	176-178 ºC
BRN	8324923
CAS DataBase Reference	69327-76-0(CAS DataBase Reference)
FDA 21 CFR	175.300
EWG's Food Scores	1
FDA UNII	3B8KGI239I
NIST Chemistry Reference	4H-1,3,5-thiadiazin-4-one, 2-((1,1-dimethylethyl)imino)tetrahydro-3-(1-methylethyl)-5-phenyl-(69327-76-0)
EPA Substance Registry System	Buprofezin (69327-76-0)
Pesticides Freedom of Information Act (FOIA)	Buprofezin

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS08,GHS09
Signal word	Warning
Hazard statements	H373-H410
Precautionary statements	P260-P273-P314-P391-P501
RIDADR	UN3077(solid)
WGK Germany	2
RTECS	XI2865000
Toxicity	LD50 in mice, rats (mg/kg): 10000, 8740 orally; LC50 (48 hr) in carp: 2-10 mg/l (Kanno, 1981)

Buprofezin price More Price(7)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	37886	Buprofezin PESTANAL?, analytical standard	69327-76-0	100mg	$108	2024-03-01	Buy
Cayman Chemical	24137	Buprofezin ≥95%	69327-76-0	50mg	$33	2024-03-01	Buy
Cayman Chemical	24137	Buprofezin ≥95%	69327-76-0	100mg	$62	2024-03-01	Buy
TRC	B689670	Buprofezin	69327-76-0	250mg	$145	2021-12-16	Buy
American Custom Chemicals Corporation	API0001787	BUPROFEZIN 95.00%	69327-76-0	5MG	$550	2021-12-16	Buy

Product number	Packaging	Price	Buy
37886	100mg	$108	Buy
24137	50mg	$33	Buy
24137	100mg	$62	Buy
B689670	250mg	$145	Buy
API0001787	5MG	$550	Buy

Buprofezin Chemical Properties,Uses,Production

Uses

Buprofezin is a contact and ingested insecticide, active against Homoptera (whiteflies, leafhoppers, scale insects, etc.) in and on citrus, cotton, cucumbers, tomatoes, sweet potatoes, rice, etc.

Uses

Insecticide.

Uses

Buprofezin is a insecticide which works as a chitin synthesis inhibitor. Buprofezin is used to control stubborn rice pests and is effective in controlling green leaf hoppers and white back plant hoppe rs for long durations.

Definition

ChEBI: Buprofezin is a 2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one in which the C=N double bond has Z configuration. It has a role as an insecticide and a member of homopteran inhibitor of chitin biosynthesis.

Hazard

Moderately toxic by ingestion. Low toxic- ity by skin contact.

Agricultural Uses

Insecticide, Acaricide, Insect growth regulator: For insect control in food crops and greenhouse ornamentals.

Trade name

APPLAUD®; NNI-750®

Pharmacology

The foregoing indicates that the modes of action of buprofezin and benzoylureas could be similar or identical. However, one differing biochemical effect of buprofezin is inhibition of prostaglandin biosynthesis (33), a mechanism that has been suggested as responsible for its ovicidal activity. Subsequently, the in vitro and in vivo effects of buprofezin were found to be strongly antagonized by 20- hydroxyecdysone (34), which also affected prostaglandin biosynthesis. Thus, inhibition of both prostaglandin and chitin biosynthesis by buprofezin was prevented by 20- hydroxyecdysone, so that both effects of the insecticide are mediated via an effect on the hormone concentration or its receptor. Consequently, buprofezin seems to inhibit the drop in the 20-hydroxyecdysone titer that triggers epidermal cell proliferation, old cuticle digestion, and new cuticle deposition, but the detailed mechanism of this action has yet to be established.

Metabolic pathway

Buprofezin gradually decomposes in soils under flooded and upland conditions, with half-lives of 104 and 80 days, respectively. After 150 days, five degradation products are identified as 2-tert- butylimino-5-(4-hydroxyphenyl)-3-isopropylperhydro- 1,3,5-thiadiazin-4-one, 3-isopropyl-5-phenylperhydro- 1,3,5-thiadiazin-2,4-dione, 1-tert-butyl-3-ispropyl-5- phenylbiuret, 1-isopropyl-3-phenylurea, and phenylurea. As minor products, 2-tert-butylimino-5- phenylperhydro-1,3,5-thiadiazin-4-one or buprofezin sulfoxide are found in the flooded or in the upland soils. Since neither formation of 14CO2 nor hydroxylation is observed in the sterile soils, buprofezin seems to have undergone complete mineralization in soils under both conditions through biological transformation by soil microorganisms.

Degradation

Buprofezin (1) was degraded under acidic conditions with half-lives (DT₅₀) f 6-12 days (pH 4), 34 days (pH 6) and 65 days (pH 10) at 40 °C. Opening of the thiadiazinanone ring appeared to be the primary hydrolytic degradation pathway, to yield 1-tert-butyl-3-isopropyl-5-phenyl-2- thiobiuret (2) and N-isopropyl-N-phenylurea (3) as major products.
Buprofezin is stable to aqueous photolysis. The estimated DT₅₀ of buprofezin in distilled water when exposed to UV light was 39 days. A more complex photodegradation pathway of buprofezin in methanol was reported recently (Datta and Walia, 1997) with DT9 values of 4 hours and 15 days under UV and sunlight irradiation, respectively.

Buprofezin Preparation Products And Raw materials

Raw materials

Concentrated hydrochloric acid N-T-BUTYL-N'-ISOPROPYLTHIOUREA ISOPROPYLTHIOUREA N-Methylaniline N-Chloromethyl-N-phenylaminoformyl chloride

Toluene Chlorine Formic acid tert-Butanol Ammonium thiocyanate

Carbon tetrachloride PHOSGENE 3-Methyl-1-butanol Isopropylamine Butyl isothiocyanate

N-Methylformanilide Thiourea

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Preparation Products

Imidacloprid+Buprofenzin,W.P. Buprofezin+Isoprocarb,W.P. Buprofenzin+Monosultap,W.P.

Buprofezin Suppliers

Global( 256)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Qingdao Trust Agri Chemical Co.,Ltd	+8613573296305	aroma@qdtrustagri.com	China	301	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21634	55
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29884	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28172	58
Xiamen AmoyChem Co., Ltd	+86-86-5926051114 +8618959220845	sales@amoychem.com	China	6383	58
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	sales@chemdad.com	China	39894	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49374	58
Hebei Mojin Biotechnology Co., Ltd	+86 13288715578 +8613288715578	sales@hbmojin.com	China	12840	58
SIMAGCHEM CORP	+86-13806087780	sale@simagchem.com	China	17365	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32165	58

Supplier	Advantage
Qingdao Trust Agri Chemical Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
career henan chemical co	58
Hubei Jusheng Technology Co.,Ltd.	58
Xiamen AmoyChem Co., Ltd	58
Chongqing Chemdad Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
Hebei Mojin Biotechnology Co., Ltd	58
SIMAGCHEM CORP	58
TargetMol Chemicals Inc.	58

View Lastest Price from Buprofezin manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-11-19	Buprofezin 69327-76-0	US $32.00-80.00 / mg		99.34%	10g	TargetMol Chemicals Inc.
2024-08-27	Buprofezin 69327-76-0	US $0.00 / kg	100kg	98	10000	qingdao trust agri chemical co.,ltd
2023-01-31	Buprofezin 69327-76-0	US $0.00 / KG	1KG	99%	50000KG/month	Hebei Mojin Biotechnology Co., Ltd

Buprofezin
69327-76-0
US $32.00-80.00 / mg
99.34%
TargetMol Chemicals Inc.

Buprofezin
69327-76-0
US $0.00 / kg
98
qingdao trust agri chemical co.,ltd

Buprofezin
69327-76-0
US $0.00 / KG
99%
Hebei Mojin Biotechnology Co., Ltd

Buprofezin Spectrum

Buprofezin(69327-76-0)MS Buprofezin(69327-76-0)¹HNMR Buprofezin(69327-76-0)¹³CNMR Buprofezin(69327-76-0)IR1 Buprofezin(69327-76-0)IR2

69327-76-0(Buprofezin)Related Search:

ISOPROPYL LAURATE Isopropyl acetate Phenylhydrazine PHENYL VALERATE tert-Butyldimethylsilyl chloride

Lithium diisopropylamide 4-tert-Butylbenzyl chloride 2-Chloro-2-methylpropane 3,4'-DIAMINODIPHENYLMETHANE Isopropyl alcohol

Acetamiprid Imidacloprid DI-TERT-BUTYL ETHER Chlormezanone Isoprocarb

BROMOPYRAZONE N'-TERT-BUTYL-N,N-DIMETHYLFORMAMIDINE Buprofezin

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3,5-Thiadiazin-4-one,2-[(1,1-dimethylethyl)imino]tetrahydro-3-(1-methylethyl)-5-phenyl-4H-1 4H-1,3,5-Thiadiazin-4-one, 2-((1,1-dimethylethyl)imino)tetrahydro-3-(1-methylethyl)-5-phenyl- 4h-1,3,5-thiadiazin-4-one,2-((1,1-dimethylethyl)imino)tetrahydro-3-(1-methylet Appland Aproad buprofenzin,w.p. NNI 750 2-tert-Butylimino-3-isopropyl-5-phenyl-3,4,5,6-tetrahydro-2H-1,3,5-thiodiazin-4-one 2-tert-Butylimino-3-isopropyl-5-phenylperhydro-1,3,5-thiadiazinan-4-one (2Z)-2-([(Z)-1,1-Dimethylethyl]imino)-3-isopropyl-5-phenyl-1,3,5-thiadiazinan-4-one 2-((1,1-dimethylethyl)imino)tetrahydro-3-(1-methylethyl)-5-phenyl-4h-1,3,5-t 2-tert-Butylimino-3-isopropyl-5-phenyl-1,3,5-thiadiazinan-4-one 2-tert-Butylimino-3-isopropyl-5-phenyl-3,4,5,6-tetrahydro-2H-1,3,5-thiadiazin-4-one Burprofezin hiadiazin-4-one 2-tert-buthylimino-3-iso-propyl-5-phenyl-3,4,5,6-tetraphydro-2H-1,3,5-thiadiaziana-4-one 2-tert-Butylimino-3-isopropyl-5-phenyl-2,3,5,6-tetrahydro-4H-1,3,5-thiadiazin-4-one 2-tert-Butyliminotetrahydro-3-isopropyl-5-phenyl-4H-1,3,5-thiadiazin-4-one 2-T-BUTYLIMINO-3-ISOPROPYL-5-PHENYLPERHYDRO-1,3,5-THIADIAZINAM-4-ONE 2-((1,1-Dimethylethyl)imino)tetrahydro-3-(1-methylethyl)-5-phenyl-4H-1,3,5-thiadiazin-4-one 2-(tert-Butylimino)-3-isopropyl-5-phenylperhydro-1,3,5-thidiazin-4-one Buprofezin 100mg [69327-76-0] BUPROFEZINSTANDARD (Z)-2-(tert-butylimino)-5-(4-hydroxyphenyl)-3-isopropyl-1,3,5-thiadiazinan-4-one (Z)-buprofezin VIAPPLA hyl)-5-phenyl- PP618 BUPROFEZIN BUPROLEX APPLAUD APPLAUD(R) 2-((1,1-dimethylethyl)imino)tetrahydro-3-(1-methylethyl)-5-phenyl-4h-1,3,5-thiadiazin-4-one 2-(tert-Butylimino)-3-isopropyl-5-phenylperhydro-1,3,5-thidiazin-4-one 2-TERT-BUTYLAMINO-3-ISOPROPYL-5-PHENYL-1,3,5-THIADIAZINAN-4-ONE MARATHON BUPROFEZIN PESTANAL BUPROFEZIN, 100MG, NEAT 2-tert-Butylimino-3-isopropyl-5-phenylperhydro-1,3,5-thiadiazin-4-one 2-tert.-Butylimino-3-isopropyl-5-phenylperhydro-1,3,5-thiodiazin-4-one buprofezin (bsi,iso) 2-tert-butylimino-5-(4-hydroxyphenyl)-3-propan-2-yl-1,3,5-thiadiazinan-4-one Buprofezin@1000 μg/mL in Acetone Buprofezin @100 μg/mL in Methanol BuprofezinSolution,1,000mg/L,1ml Buprofezin Reference Material BuprofezinSolution,100mg/L,1ml Buprofezin 25%SC Insecticides for Rice potatoes citrus CAS No 69327-76-0 (EZ)-Buprofezin Buprofezine BUTYL BUPROFENZIN Mitotane-13C Buprofezin Solution in Methanol Buprofezin in Acetone Buprofezin in Methanol Buprofezin 10 μg/ml Ethyl acetate Buprofezin 100 μg/ml Acetonitrile Buprofezin 100 μg/ml Ethyl acetate