3,5-Dimethoxyphenol
- CAS No.
- 500-99-2
- Chemical Name:
- 3,5-Dimethoxyphenol
- Synonyms
- Phenol, 3,5-dimethoxy-;NSC 70955;Taxicatigenin;3,5-DIMETHOXYPHENOL;3,5-Dimethoxyphenol>3,5-Dimethoxyphenol,97%;3,5-DiMethoxyphenol 99%;DIMETHOXYPHENOL, 3,5-(P);Phloroglucinol Impurity 24;Phloroglucin dimethyl ether
- CBNumber:
- CB2268778
- Molecular Formula:
- C8H10O3
- Molecular Weight:
- 154.16
- MDL Number:
- MFCD00008388
- MOL File:
- 500-99-2.mol
- MSDS File:
- SDS
| Melting point | 40-43 °C (lit.) |
|---|---|
| Boiling point | 172-175 °C/17 mmHg (lit.) |
| Density | 1.1690 (rough estimate) |
| refractive index | 1.4745 (estimate) |
| Flash point | 173 °F |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) |
| form | Liquid |
| pka | pK1:9.345 (25°C) |
| color | Clear colorless to orange-red to pale pink-brownish |
| Water Solubility | Soluble in methanol, ethanol, benzene, water (slightly), and chloroform. |
| Sensitive | Air & Light Sensitive |
| BRN | 1239156 |
| InChIKey | XQDNFAMOIPNVES-UHFFFAOYSA-N |
| LogP | 1.640 |
| CAS DataBase Reference | 500-99-2(CAS DataBase Reference) |
| FDA UNII | 23UXW8136A |
| NIST Chemistry Reference | Phenol, 3,5-dimethoxy-(500-99-2) |
| EPA Substance Registry System | Phenol, 3,5-dimethoxy- (500-99-2) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 10 | |||||||||
| Hazard Note | Irritant | |||||||||
| HS Code | 29095090 | |||||||||
| NFPA 704 |
|
3,5-Dimethoxyphenol price More Price(35)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 132632 | 3,5-Dimethoxyphenol 99% | 500-99-2 | 10g | $106 | 2024-03-01 | Buy |
| Sigma-Aldrich | 132632 | 3,5-Dimethoxyphenol 99% | 500-99-2 | 50g | $165 | 2024-03-01 | Buy |
| TCI Chemical | P0320 | 3,5-Dimethoxyphenol >98.0%(GC) | 500-99-2 | 25g | $149 | 2024-03-01 | Buy |
| TCI Chemical | P0320 | 3,5-Dimethoxyphenol >98.0%(GC) | 500-99-2 | 100g | $447 | 2024-03-01 | Buy |
| Alfa Aesar | B22283 | 3,5-Dimethoxyphenol, 98% | 500-99-2 | 10g | $76.65 | 2024-03-01 | Buy |
3,5-Dimethoxyphenol Chemical Properties,Uses,Production
Chemical Properties
slightly pink to yellow crystalline powder
Uses
3,5-dimethoxyphenol is a marker for poisoning from Taxus baccata.
Uses
3,5-Dimethoxyphenol is a phenol derivative as antinitrosating agent.
Definition
ChEBI: 3,5-Dimethoxyphenol is a member of methoxybenzenes and a member of phenols.
Synthesis
Ethanethiol (1.25g, 1.5 ml, 0.02 mole) dissolved in N, N- dimethyl-formamide (20 ml) is added to a suspension of sodium hydride (1 g of 50%oil dispersion) in dry DMF (10 ml) under an atmosphere of nitrogen. The mixture is stirred for 5 min under anhydrous conditions. A solution of phloroglucinol trimethyl ether (1.14) (1 g,0.006 moles) in dry DMF (10 ml)is added, and the mixture is refluxed for 3 hr. The reaction mixture is cooled and acidified with hydrochloric acid (10%). It is extracted with ether(3 x 50 ml). The ether extract is washed with water and extracted with sodium hydroxide solution (5%). The clear alkaline extract is acidified with hydrochloric acid. The mixture is extracted with ether. The ether extract is washed with water, ried (anhydrous sodium sulphate), and drilled. 3,5-Dimethoxyphenol is obtained as an oil. Yield 0.9 g (98.1%).B.p.198-199°/30 mm.
Purification Methods
Purify the phenol by distillation followed by sublimation in a vacuum. [Beilstein 6 IV 7362.]
3,5-Dimethoxyphenol Preparation Products And Raw materials
Raw materials
Preparation Products
1of2
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32957 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29884 | 58 |
| Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 | sales@pioneerbiotech.com | China | 3000 | 58 |
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14332 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49374 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569266 15319487004 | 1015@dideu.com | China | 4084 | 58 |
View Lastest Price from 3,5-Dimethoxyphenol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-19 | 3,5-Dimethoxyphenol
500-99-2
|
US $29.00 / g | 98% | 10g | TargetMol Chemicals Inc. | ||
 |
2022-02-19 | 3,5-Dimethoxyphenol
500-99-2
|
US $0.00 / KG | 1KG | 97.0% | 100 tons | Honest Joy Holdings Limited
|
|
 |
2019-07-06 | 3,5-Dimethoxyphenol
500-99-2
|
US $8.00 / kg | 1kg | 99% | 10MT | Career Henan Chemical Co |
-
- 3,5-Dimethoxyphenol
500-99-2
- US $29.00 / g
- 98%
- TargetMol Chemicals Inc.
-
- 3,5-Dimethoxyphenol
500-99-2
- US $0.00 / KG
- 97.0%
- Honest Joy Holdings Limited
-
- 3,5-Dimethoxyphenol
500-99-2
- US $8.00 / kg
- 99%
- Career Henan Chemical Co