ChemicalBook >> CAS DataBase List >>Abacavir Related CoMpound D
Abacavir Related CoMpound D
- CAS No.
- 1443421-69-9
- Chemical Name:
- Abacavir Related CoMpound D
- Synonyms
- Abacavir EP Imp B;Abacavir Impurity B;Abacavir Impurity D;Abacavir EP Impurity B;ABACAVIR O-PYRIMIDYL IMP;Abacavir Related CoMpound D;O-Pyrimidine Derivative Abacavir (USP);Abacavir Impurity 2(Abacavir EP Impurity B);Abacavir 5'-4-Chloro-6-methylpyrimidine-2,5-diamine;N6-Cyclopropyl-9-{(1R,4S)-4-[(2,5-diamino-6-chloropyrimidin-4-yloxy)methyl]cyclopent-2-enyl}-9H-purine-2,6-diamine
- CBNumber:
- CB22714699
- Molecular Formula:
- C18H21ClN10O
- Molecular Weight:
- 428.88
- MDL Number:
- MFCD28137825
- MOL File:
- 1443421-69-9.mol
- MSDS File:
- SDS
Last updated:2022-12-21 16:56:50
| Boiling point | 830.1±75.0 °C(Predicted) |
|---|---|
| Density | 1.90±0.1 g/cm3(Predicted) |
| pka | 4.86±0.10(Predicted) |
| FDA UNII | 8YR0EYX97M |
Abacavir Related CoMpound D price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 1000437 | Abacavir Related Compound D | 1443421-69-9 | 20mg | $1360 | 2024-03-01 | Buy |
| TRC | A105035 | Abacavir5’-4-Chloro-6-methylpyrimidine-2,5-diamine | 1443421-69-9 | 25mg | $1050 | 2021-12-16 | Buy |
| TRC | A105035 | Abacavir5’-4-Chloro-6-methylpyrimidine-2,5-diamine | 1443421-69-9 | 2.5mg | $130 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0027217 | ABACAVIR O-PYRIMIDINE IMPURITY 95.00% | 1443421-69-9 | 5MG | $504.96 | 2021-12-16 | Buy |
Abacavir Related CoMpound D Chemical Properties,Uses,Production
Uses
Abacavir 5’-4-Chloro-6-methylpyrimidine-2,5-diamine (Abacavir EP Impurity B) is a degradation product of Abacavir Sulfate (A105000). Abacavir is a carbocyclic 2''-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.
Abacavir Related CoMpound D Preparation Products And Raw materials
Raw materials
Preparation Products
Abacavir Related CoMpound D Suppliers
Global( 36)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14332 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| CR Corporation Limited | +8613062833949 | fred.wen@crcorporation.cn | China | 8647 | 58 |
| sgtlifesciences pvt ltd | +8617013299288 | dj@sgtlifesciences.com | China | 12373 | 58 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 010-50973186 4009686088 | 3193328036@qq.com | China | 18338 | 68 |
| Shanghai CR Corporation Limited | 021-80270511; 4006653949 | fred.wen@crcorporation.cn | China | 10044 | 58 |
| Shenzhen SUNGENING Bio-Medical Co., Ltd. | 0755-28967200 13631290199 | wxf@sungening.com | China | 9577 | 60 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 +86-13028896684; | sales@rrkchem.com | China | 57412 | 58 |
| Shenzhen Botel Biotechnology Co. Ltd. | 0755-22202135 13316968096 | 1979313431@qq.com | China | 8967 | 58 |
| TOSUN PHARM | 020-61855200 13326451905 | 260366801@qq.com | China | 7781 | 58 |
1443421-69-9(Abacavir Related CoMpound D)Related Search:
Abacavir sulfate
2-Cyclopentene-1-methanol, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, (1R-cis)-
Abacavir
(1S–4R)-4-(2-amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol hydrochloride
6-aminocarbovir
1of4
Abacavir Related CoMpound D
N6-Cyclopropyl-9-{(1R,4S)-4-[(2,5-diamino-6-chloropyrimidin-4-yloxy)methyl]cyclopent-2-enyl}-9H-purine-2,6-diamine
Abacavir 5'-4-Chloro-6-methylpyrimidine-2,5-diamine
Abacavir EP Impurity B
O-Pyrimidine Derivative Abacavir (USP)
6-(Cyclopropylamino)-9-[(1R,4S)-4-[[(2,5-diamino-6-chloropyrimidin-4-yl)oxy]methyl]cyclopent-2-enyl]-9H-purine-2-amine
9H-Purine-2,6-diamine, N6-cyclopropyl-9-[(1R,4S)-4-[[(2,5-diamino-6-chloro-4-pyrimidinyl)oxy]methyl]-2-cyclopenten-1-yl]-
Abacavir Impurity D
Abacavir Impurity B
6-N-Cyclopropyl-9-[(1R,4S)-4-[[(2,5-diamino-6-chloro-4- pyrimidinyl)oxy]methyl]cyclopent-2-en-1-yl]-9H-purine-2,6- diamine
Abacavir EP Imp B
Abacavir Impurity 2(Abacavir EP Impurity B)
ABACAVIR O-PYRIMIDYL IMP
N6-Cyclopropyl-9-((1R,4S)-4-(((2,5-Diamino-6-chloropyrimidin-4-yl)oxy)methyl)cyclopent-2-en-1-yl)-9H-purine-2,6-diamine (Abacavir Impurity)
Abacavir Related Compound D (20 mg) (N6-Cyclopropyl-9-{(1R,4S)-4-[(2,5-diamino-6-chloropyrimidin-4-yloxy)methyl]cyclopent-2-enyl}-9H-purine-2,6-diamine)
1443421-69-9
C18H21ClN10O