1-oleoyl-2-{6-[4-(dipyrroMetheneboron difluoride)butanoyl]aMino}hexanoyl-sn-glycero-3-phosphoinositol-4,5-bisphosphate (aMMoniuM salt)
- CAS No.
- 1246355-57-6
- Chemical Name:
- 1-oleoyl-2-{6-[4-(dipyrroMetheneboron difluoride)butanoyl]aMino}hexanoyl-sn-glycero-3-phosphoinositol-4,5-bisphosphate (aMMoniuM salt)
- Synonyms
- TopFluor PI(4;1-oleoyl-2-{6-[4-(dipyrroMetheneboron difluoride)butanoyl]aMino}hexanoyl-sn-glycero-3-phosphoinositol-4,5-bisphosphate (aMMoniuM salt);1-OLEOYL-2-{6-[4-(DIPYRROMETHENEBORON DIFLUORIDE)BUTANOYL]AMINO}HEXANOYL-SN-GLYCERO-3-PHOSPHOINOSITOL-4,5-BISPHOSPHATE (AMMONIUM SALT);TOPFLUOR PI(4;5)P2
- CBNumber:
- CB22719775
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD22416762
- MOL File:
- Mol file
1-oleoyl-2-{6-[4-(dipyrroMetheneboron difluoride)butanoyl]aMino}hexanoyl-sn-glycero-3-phosphoinositol-4,5-bisphosphate (aMMoniuM salt) Chemical Properties,Uses,Production
Uses
TopFluor? PI(4,5)P2 or 1-oleoyl-2-{6-[4-(dipyrrometheneboron difluoride)butanoyl]amino}hexanoyl-sn-glycero-3-phosphoinositol-4,5-bisphosphate (ammonium salt) has been used as a fluorescent lipid in living cells to analyse the cellular localization of phosphatidylinositol (PI) and in the preparation of giant unilamellar vesicles (GUVs) for the ezrin-membrane tethering assays.
General Description
Although PI(4,5)P2 is a minor component of cell membranes, it plays a critical role as a substrate for a number of important signaling proteins. PI(4,5)P2 is an intermediate in the IP3/DAG pathway where it is hydrolyzed by phospholipase C to liberate the second messengers, inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG). PI(4,5)P2 is also a substrate for PI 3-kinase where it is phosphorylated to PI(3,4,5)P3, an activator of downstream signaling components such as the protein kinase AKT.
1-oleoyl-2-{6-[4-(dipyrroMetheneboron difluoride)butanoyl]aMino}hexanoyl-sn-glycero-3-phosphoinositol-4,5-bisphosphate (aMMoniuM salt) Preparation Products And Raw materials
Raw materials
Preparation Products
1-oleoyl-2-{6-[4-(dipyrroMetheneboron difluoride)butanoyl]aMino}hexanoyl-sn-glycero-3-phosphoinositol-4,5-bisphosphate (aMMoniuM salt) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Creative Enzymes | 1-516-855-7709 | info@creative-enzymes.com | United States | 8748 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| Chengdu Dianchun Technology Co., Ltd | 400-1166-196 18502815961 | cdhxsj@163.com | China | 14623 | 60 |
| Supplier | Advantage |
|---|---|
| Creative Enzymes | 58 |
| Aladdin Scientific | 58 |
| Chengdu Dianchun Technology Co., Ltd | 60 |