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ChemicalBook >> CAS DataBase List >>N-{4-[4-(2,3-Dichlorophenyl)-piperazin-1-yl]-trans-but-2-enyl}-4-(pyridin-2-yl)benzamide dihydrochloride hydrate

N-{4-[4-(2,3-Dichlorophenyl)-piperazin-1-yl]-trans-but-2-enyl}-4-(pyridin-2-yl)benzamide dihydrochloride hydrate

N-{4-[4-(2,3-Dichlorophenyl)-piperazin-1-yl]-trans-but-2-enyl}-4-(pyridin-2-yl)benzamide dihydrochloride hydrate Structure
N-{4-[4-(2,3-Dichlorophenyl)-piperazin-1-yl]-trans-but-2-enyl}-4-(pyridin-2-yl)benzamide dihydrochloride hydrate structure
CAS No.
675599-62-9
Chemical Name:
N-{4-[4-(2,3-Dichlorophenyl)-piperazin-1-yl]-trans-but-2-enyl}-4-(pyridin-2-yl)benzamide dihydrochloride hydrate
Synonyms
PG 01037 2HCl;PG-01037 (hydrochloride);PG01037 dihydrochloride hydrate;N-[(2E)-4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]-2-buten-1-yl]-4-(2-pyridyl)benzamide dihydrochloride hydrate;N-{4-[4-(2,3-Dichlorophenyl)-piperazin-1-yl]-trans-but-2-enyl}-4-(pyridin-2-yl)benzamide dihydrochloride hydrate
CBNumber:
CB22750471
Molecular Formula:
C26H30Cl4N4O2
Molecular Weight:
572.354
MDL Number:
MFCD20527309
MOL File:
675599-62-9.mol
Last updated:2024-11-19 23:02:33
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N-{4-[4-(2,3-Dichlorophenyl)-piperazin-1-yl]-trans-but-2-enyl}-4-(pyridin-2-yl)benzamide dihydrochloride hydrate Properties

Melting point 230-232 °C(Solv: isopropanol (67-63-0))
storage temp. 2-8°C
solubility H2O: ≥8mg/mL at ~60°C
form powder
color white to tan
FDA UNII MV7454V7DG

SAFETY

Risk and Safety Statements

WGK Germany  3

N-{4-[4-(2,3-Dichlorophenyl)-piperazin-1-yl]-trans-but-2-enyl}-4-(pyridin-2-yl)benzamide dihydrochloride hydrate price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 22079 PG-01037 (hydrochloride) ≥98% 675599-62-9 1mg $32 2024-03-01 Buy
Cayman Chemical 22079 PG-01037 (hydrochloride) ≥98% 675599-62-9 5mg $100 2024-03-01 Buy
Cayman Chemical 22079 PG-01037 (hydrochloride) ≥98% 675599-62-9 10mg $184 2024-03-01 Buy
Cayman Chemical 22079 PG-01037 (hydrochloride) ≥98% 675599-62-9 25mg $420 2024-03-01 Buy
TRC P294213 PG01037Dihydrochloride 675599-62-9 10mg $115 2021-12-16 Buy
Product number Packaging Price Buy
22079 1mg $32 Buy
22079 5mg $100 Buy
22079 10mg $184 Buy
22079 25mg $420 Buy
P294213 10mg $115 Buy

N-{4-[4-(2,3-Dichlorophenyl)-piperazin-1-yl]-trans-but-2-enyl}-4-(pyridin-2-yl)benzamide dihydrochloride hydrate Chemical Properties,Uses,Production

Description

PG-01037 is a selective dopamine D3 receptor antagonist (Kis = 0.7, 93, and 375 nM for HEK293 cells expressing human D3, D2, and D4 receptors, respectively). It inhibits quinpirole-induced stimulation of mitogenesis in CHO cells expressing human dopamine D3 receptors (EC50 = 3 nM). PG-01037 (32 mg/kg) reduces progressive-ratio methamphetamine self-administration in rats allowed extended access. It reduces loss of dopaminergic neurons in the substantia nigra pars compacta and improves motor performance in the coat-hanger test in a mouse model of Parkinson''s disease induced by MPTP.

Uses

PG01037 dihydrochloride is a selective D3DR antagonist.

storage

Desiccate at +4°C

N-{4-[4-(2,3-Dichlorophenyl)-piperazin-1-yl]-trans-but-2-enyl}-4-(pyridin-2-yl)benzamide dihydrochloride hydrate Preparation Products And Raw materials

Raw materials

Preparation Products

N-{4-[4-(2,3-Dichlorophenyl)-piperazin-1-yl]-trans-but-2-enyl}-4-(pyridin-2-yl)benzamide dihydrochloride hydrate Suppliers

Global( 16)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32165 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 57505 58
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8447 60
MQ (shanghai) Pharmaceuticals Co., Ltd. 13761635123 1014988033@qq.com China 4983 55
BOC Sciences -- info@bocsci.com USA 0 65
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11217 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8140 58
Jinan Jiuli Biotechnology Co. , Ltd. 15865264761 486064515@qq.com China 3732 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24647 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11974 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Aladdin Scientific 		58
EMMX Biotechnology LLC 60
MQ (shanghai) Pharmaceuticals Co., Ltd. 55
BOC Sciences 65
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
MedBioPharmaceutical Technology Inc 58
Jinan Jiuli Biotechnology Co. , Ltd. 58
TargetMol Chemicals Inc. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58

View Lastest Price from N-{4-[4-(2,3-Dichlorophenyl)-piperazin-1-yl]-trans-but-2-enyl}-4-(pyridin-2-yl)benzamide dihydrochloride hydrate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
PG 01037 dihydrochloride pictures 2024-11-19 PG 01037 dihydrochloride
675599-62-9
 US $35.00-75.00 / mg 99.77% 10g TargetMol Chemicals Inc.

N-{4-[4-(2,3-Dichlorophenyl)-piperazin-1-yl]-trans-but-2-enyl}-4-(pyridin-2-yl)benzamide dihydrochloride hydrate Spectrum

N-{4-[4-(2,3-Dichlorophenyl)-piperazin-1-yl]-trans-but-2-enyl}-4-(pyridin-2-yl)benzamide dihydrochloride hydrate(675599-62-9)1HNMR
N-[(2E)-4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]-2-buten-1-yl]-4-(2-pyridyl)benzamide dihydrochloride hydrate N-{4-[4-(2,3-Dichlorophenyl)-piperazin-1-yl]-trans-but-2-enyl}-4-(pyridin-2-yl)benzamide dihydrochloride hydrate PG01037 dihydrochloride hydrate PG-01037 (hydrochloride) PG 01037 2HCl 675599-62-9