N-{4-[4-(2,3-Dichlorophenyl)-piperazin-1-yl]-trans-but-2-enyl}-4-(pyridin-2-yl)benzamide dihydrochloride hydrate
![N-{4-[4-(2,3-Dichlorophenyl)-piperazin-1-yl]-trans-but-2-enyl}-4-(pyridin-2-yl)benzamide dihydrochloride hydrate price.](/CAS/20180629/GIF/675599-62-9.gif)
|
- $32 - $1305
- Product name: N-{4-[4-(2,3-Dichlorophenyl)-piperazin-1-yl]-trans-but-2-enyl}-4-(pyridin-2-yl)benzamide dihydrochloride hydrate
- CAS: 675599-62-9
- MF: C26H30Cl4N4O2
- MW: 572.354
- EINECS:
- MDL Number:MFCD20527309
- Synonyms:N-[(2E)-4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]-2-buten-1-yl]-4-(2-pyridyl)benzamide dihydrochloride hydrate;N-{4-[4-(2,3-Dichlorophenyl)-piperazin-1-yl]-trans-but-2-enyl}-4-(pyridin-2-yl)benzamide dihydrochloride hydrate;PG01037 dihydrochloride hydrate;PG-01037 (hydrochloride)
9 prices
Selected condition：
Brand
- AK Scientific
- ApexBio Technology
- Cayman Chemical
- TRC
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- ManufacturerAK Scientific
- Product number4505EB
- Product descriptionPG01037dihydrochloride
- Packaging1mg
- Price$133
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number4505EB
- Product descriptionPG01037dihydrochloride
- Packaging5mg
- Price$209
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7524
- Product descriptionPG01037dihydrochloride
- Packaging10mg
- Price$322
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7524
- Product descriptionPG01037dihydrochloride
- Packaging50mg
- Price$1305
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number22079
- Product descriptionPG-01037 (hydrochloride) ≥98%
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number22079
- Product descriptionPG-01037 (hydrochloride) ≥98%
- Packaging5mg
- Price$100
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number22079
- Product descriptionPG-01037 (hydrochloride) ≥98%
- Packaging10mg
- Price$184
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number22079
- Product descriptionPG-01037 (hydrochloride) ≥98%
- Packaging25mg
- Price$420
- Updated2024-03-01
- Buy
- ManufacturerTRC
- Product numberP294213
- Product descriptionPG01037Dihydrochloride
- Packaging10mg
- Price$115
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 4505EB | PG01037dihydrochloride | 1mg | $133 | 2021-12-16 | Buy |
| AK Scientific | 4505EB | PG01037dihydrochloride | 5mg | $209 | 2021-12-16 | Buy |
| ApexBio Technology | B7524 | PG01037dihydrochloride | 10mg | $322 | 2021-12-16 | Buy |
| ApexBio Technology | B7524 | PG01037dihydrochloride | 50mg | $1305 | 2021-12-16 | Buy |
| Cayman Chemical | 22079 | PG-01037 (hydrochloride) ≥98% | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 22079 | PG-01037 (hydrochloride) ≥98% | 5mg | $100 | 2024-03-01 | Buy |
| Cayman Chemical | 22079 | PG-01037 (hydrochloride) ≥98% | 10mg | $184 | 2024-03-01 | Buy |
| Cayman Chemical | 22079 | PG-01037 (hydrochloride) ≥98% | 25mg | $420 | 2024-03-01 | Buy |
| TRC | P294213 | PG01037Dihydrochloride | 10mg | $115 | 2021-12-16 | Buy |
Properties
Melting point :230-232 °C(Solv: isopropanol (67-63-0))
storage temp. :2-8°C
solubility :H2O: ≥8mg/mL at ~60°C
form :powder
color :white to tan
storage temp. :2-8°C
solubility :H2O: ≥8mg/mL at ~60°C
form :powder
color :white to tan
Safety Information
| Symbol(GHS): | ||||||||
|---|---|---|---|---|---|---|---|---|
| Signal word: | ||||||||
| Hazard statements: |
|
|||||||
| Precautionary statements: |
|
Description
PG-01037 is a selective dopamine D3 receptor antagonist (Kis = 0.7, 93, and 375 nM for HEK293 cells expressing human D3, D2, and D4 receptors, respectively). It inhibits quinpirole-induced stimulation of mitogenesis in CHO cells expressing human dopamine D3 receptors (EC50 = 3 nM). PG-01037 (32 mg/kg) reduces progressive-ratio methamphetamine self-administration in rats allowed extended access. It reduces loss of dopaminergic neurons in the substantia nigra pars compacta and improves motor performance in the coat-hanger test in a mouse model of Parkinson''s disease induced by MPTP.Suppliers and manufacturers
TargetMol Chemicals Inc.
Aladdin Scientific
EMMX Biotechnology LLC
MQ (shanghai) Pharmaceuticals Co., Ltd.
BOC Sciences
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
MedBioPharmaceutical Technology Inc
TargetMol Chemicals Inc.
Shanghai Yifei Biotechnology Co. , Ltd.
Shanghai Aladdin Biochemical Technology Co.,Ltd.