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ChemicalBook >> CAS DataBase List >>Tetrahydro-4-[3-[[4-(2-methyl-1H-imidazol-1-yl)phenyl]thio]phenyl]-2H-pyran-4-carboxamide

Tetrahydro-4-[3-[[4-(2-methyl-1H-imidazol-1-yl)phenyl]thio]phenyl]-2H-pyran-4-carboxamide

Tetrahydro-4-[3-[[4-(2-methyl-1H-imidazol-1-yl)phenyl]thio]phenyl]-2H-pyran-4-carboxamide Structure
Tetrahydro-4-[3-[[4-(2-methyl-1H-imidazol-1-yl)phenyl]thio]phenyl]-2H-pyran-4-carboxamide structure
CAS No.
179420-17-8
Chemical Name:
Tetrahydro-4-[3-[[4-(2-methyl-1H-imidazol-1-yl)phenyl]thio]phenyl]-2H-pyran-4-carboxamide
Synonyms
CJ-13610;CJ-13610 (CJ13610);CJ-13610 >=98% (HPLC);Tetrahydro-4-[3-[[4-(2-methyl-1H-imidazol-1-yl)phenyl]thio]phenyl]-2H-pyran-4-carboxamide;2H-Pyran-4-carboxamide, tetrahydro-4-[3-[[4-(2-methyl-1H-imidazol-1-yl)phenyl]thio]phenyl]-;4-(3-((4-(2-METHYL-1H-IMIDAZOL-1-YL)PHENYL)SULFANYL)PHENYL)TETRAHYDRO-2H-PYRAN-4-CARBOXAMIDE;Lipoxygenase,inhibit,CJ 13,610,LOX,nonredox-type,polymorphonuclear leukocytes,Inhibitor,CJ-13,610,arachidonic acid,CJ13,610
CBNumber:
CB22750572
Molecular Formula:
C22H23N3O2S
Molecular Weight:
393.5
MDL Number:
MFCD00948114
MOL File:
179420-17-8.mol
MSDS File:
SDS
Last updated:2023-05-18 11:31:03
Request For Quotation

Tetrahydro-4-[3-[[4-(2-methyl-1H-imidazol-1-yl)phenyl]thio]phenyl]-2H-pyran-4-carboxamide Properties

Melting point 208-210 °C
Boiling point 681.0±65.0 °C(Predicted)
Density 1.27±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: ≥10mg/mL
form powder
pka 15.77±0.20(Predicted)
color white to tan
FDA UNII 5275PJ1C59

SAFETY

Risk and Safety Statements

WGK Germany  3

Tetrahydro-4-[3-[[4-(2-methyl-1H-imidazol-1-yl)phenyl]thio]phenyl]-2H-pyran-4-carboxamide price More Price(7)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML0187 CJ-13610 ≥98% (HPLC) 179420-17-8 5mg $130 2024-03-01 Buy
Sigma-Aldrich SML0187 CJ-13610 ≥98% (HPLC) 179420-17-8 25mg $505 2024-03-01 Buy
Cayman Chemical 21764 CJ-13610 ≥98% 179420-17-8 1mg $44 2024-03-01 Buy
Cayman Chemical 21764 CJ-13610 ≥98% 179420-17-8 5mg $118 2024-03-01 Buy
Cayman Chemical 21764 CJ-13610 ≥98% 179420-17-8 10mg $214 2024-03-01 Buy
Product number Packaging Price Buy
SML0187 5mg $130 Buy
SML0187 25mg $505 Buy
21764 1mg $44 Buy
21764 5mg $118 Buy
21764 10mg $214 Buy

Tetrahydro-4-[3-[[4-(2-methyl-1H-imidazol-1-yl)phenyl]thio]phenyl]-2H-pyran-4-carboxamide Chemical Properties,Uses,Production

Uses

CJ-13610 may be used to study 5-lipoxygenase-mediated cell signaling.

Biochem/physiol Actions

CJ-13610 inhibits the biosynthesis of leukotriene B4 and regulates the IL-6 mRNA expression in macrophages. It reduces fibrosis and necroinflammation of liver in carbon tetrachloride-treated mice.

Tetrahydro-4-[3-[[4-(2-methyl-1H-imidazol-1-yl)phenyl]thio]phenyl]-2H-pyran-4-carboxamide synthesis

130723-54-5
179420-17-8
Synthesis of Tetrahydro-4-[3-[[4-(2-methyl-1H-imidazol-1-yl)phenyl]thio]phenyl]-2H-pyran-4-carboxamide from 3-IODOPHENYLACETONITRILE

Tetrahydro-4-[3-[[4-(2-methyl-1H-imidazol-1-yl)phenyl]thio]phenyl]-2H-pyran-4-carboxamide Preparation Products And Raw materials

Raw materials

Preparation Products

Tetrahydro-4-[3-[[4-(2-methyl-1H-imidazol-1-yl)phenyl]thio]phenyl]-2H-pyran-4-carboxamide Suppliers

Global( 25)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6313 58
Guangzhou Isun Pharmaceutical Co., Ltd 020-39119399 18927568969 isunpharm@qq.com China 4428 55
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 sales-cpd@caerulumpharma.com China 3465 58
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9707 58
DC Chemicals 021-58447131 13564518121 sales@dcchemicals.com China 9412 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Suzhou Chenrui Biotechnology Co. LTD 17625585511 1580084073@qq.com China 529 58
Energy Chemical 021-58432009 400-005-6266 marketing1@energy-chemical.com China 44843 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		58
Guangzhou Isun Pharmaceutical Co., Ltd 55
ShangHai Caerulum Pharma Discovery Co., Ltd. 58
Sigma-Aldrich 80
Shanghai EFE Biological Technology Co., Ltd. 58
DC Chemicals 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Suzhou Chenrui Biotechnology Co. LTD 58
Energy Chemical 58
Tetrahydro-4-[3-[[4-(2-methyl-1H-imidazol-1-yl)phenyl]thio]phenyl]-2H-pyran-4-carboxamide CJ-13610 CJ-13610 >=98% (HPLC) 2H-Pyran-4-carboxamide, tetrahydro-4-[3-[[4-(2-methyl-1H-imidazol-1-yl)phenyl]thio]phenyl]- CJ-13610 (CJ13610) 4-(3-((4-(2-METHYL-1H-IMIDAZOL-1-YL)PHENYL)SULFANYL)PHENYL)TETRAHYDRO-2H-PYRAN-4-CARBOXAMIDE Lipoxygenase,inhibit,CJ 13,610,LOX,nonredox-type,polymorphonuclear leukocytes,Inhibitor,CJ-13,610,arachidonic acid,CJ13,610 179420-17-8