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DBCO-PEG4-SE

CAS No.
1427004-19-0
Chemical Name:
DBCO-PEG4-SE
Synonyms
DBCO-PEG4-SE;DBCO-PEG4-NHS;DBCO-PEG4-SPA;DBCO-PEG4-NHS easer;DBCO-PEG4-NHS ester;DBCO-CONH-PEG4-NHS ester;DBCO-PEG4-succinimidyl ester;Dibenzocyclooctyne-PEG4-N-hydroxysuccinimidyl ester;inhibit,Inhibitor,DBCO PEG4 NHS ester,DBCOPEG4NHS ester,DBCO-PEG-4-NHS ester,PROTAC Linkers;2,5-Dioxo-1-pyrrolidinyl 20-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-17,20-dioxo-4,7,10,13-tetraoxa-16-azaeicosanoate
CBNumber:
CB22984375
Molecular Formula:
C34H39N3O10
Molecular Weight:
649.69
MDL Number:
MFCD26793797
MOL File:
1427004-19-0.mol
Last updated:2024-11-19 23:02:33

DBCO-PEG4-SE Properties

Density 1.33±0.1 g/cm3(Predicted)
storage temp. -20°C
solubility Soluble in DMSO, DCM, DMF
pka 15.14±0.46(Predicted)
form gel or oil
color Colourless to yellow
InChIKey RRCXYKNJTKJNTD-UHFFFAOYSA-N
SMILES C(ON1C(=O)CCC1=O)(=O)CCOCCOCCOCCOCCNC(=O)CCC(N1CC2=CC=CC=C2C#CC2=CC=CC=C12)=O

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
WGK Germany  3
HS Code  2942000090

DBCO-PEG4-SE price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 764019 Dibenzocyclooctyne-PEG4-N-hydroxysuccinimidyl ester 95% 1427004-19-0 1MG $37 2023-06-20 Buy
Sigma-Aldrich 764019 Dibenzocyclooctyne-PEG4-N-hydroxysuccinimidyl ester 95% 1427004-19-0 5MG $118 2023-06-20 Buy
Sigma-Aldrich 764019 Dibenzocyclooctyne-PEG4-N-hydroxysuccinimidyl ester 95% 1427004-19-0 50MG $510 2023-06-20 Buy
TRC D195020 DBCO-PEG4-NHSEster 1427004-19-0 1mg $45 2021-12-16 Buy
Chem-Impex 35051 DBCO-PEG4-NHSester,95% 95% 1427004-19-0 5MG $56 2021-12-16 Buy
Product number Packaging Price Buy
764019 1MG $37 Buy
764019 5MG $118 Buy
764019 50MG $510 Buy
D195020 1mg $45 Buy
35051 5MG $56 Buy

DBCO-PEG4-SE Chemical Properties,Uses,Production

Description

DBCO-PEG4-NHS Ester is a click chemistry PEG reagent containing NHS ester that is able to react specifically and efficiently with primary amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic condition to form a covalent bond. The hydrophilic PEG spacer arm improves water solubility and provides a long and flexible connection that minimizes steric hindrance involved with ligation. DBCO is commonly used for copper-free Click Chemistry reactions.

Uses

Succinimidyl ester (NHS, amine reactive) functionalized cyclooctyne derivative for incorporation of the cyclooctyne moiety into amine containing compounds or biomolecules. Cyclooctynes are useful in strain-promoted copper-free click chemistry cycloaddition reactions. This dibenzocyclooctyne will react with azide functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage.

Applications Include:

  • Protein-peptide conjugates
  • Antibody-enzyme or antibody-drug conjugates
  • Protein or peptide-oligonucleotide conjugates
  • Surface modification

DBCO-PEG4-SE Preparation Products And Raw materials

Raw materials

Preparation Products

DBCO-PEG4-SE Suppliers

Global( 80)Suppliers
Supplier Tel Email Country ProdList Advantage
Xian confluore Biological Technology Co., Ltd.
+86-15680926068 +86-15680926068 1924344760@confluore.cn China 2995 58
9i LLC
+18039569191 MWan@NiNeiLab.com United States 418 58
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32957 60
Shenzhen Nexconn Pharmatechs Ltd
+86-755-89396905 +86-15013857715 admin@nexconn.com China 10310 58
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19553 58
Chongqing Chemdad Co., Ltd
+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39894 58
Zhengzhou Alfa Chemical Co.,Ltd
+8618530059196 sale04@alfachem.cn China 13503 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32165 58
Wuhan Borenpharm Co., Ltd
027-65563561 18717150066 3207347307@qq.com CHINA 1238 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10473 58

View Lastest Price from DBCO-PEG4-SE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
DBCO-PEG4-NHS ester pictures 2024-11-19 DBCO-PEG4-NHS ester
1427004-19-0
US $59.00-247.00 / mg ≥98% 10g TargetMol Chemicals Inc.
DBCO-PEG4-NHS ester pictures 2024-03-20 DBCO-PEG4-NHS ester
1427004-19-0
US $0.00 / mg 50mg >99.00% 250 Xian confluore Biological Technology Co., Ltd.
  • DBCO-PEG4-NHS ester pictures
  • DBCO-PEG4-NHS ester
    1427004-19-0
  • US $0.00 / mg
  • >99.00%
  • Xian confluore Biological Technology Co., Ltd.
DBCO-PEG4-NHS ester DBCO-PEG4-SE DBCO-PEG4-succinimidyl ester Dibenzocyclooctyne-PEG4-N-hydroxysuccinimidyl ester DBCO-CONH-PEG4-NHS ester 2,5-Dioxo-1-pyrrolidinyl 20-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-17,20-dioxo-4,7,10,13-tetraoxa-16-azaeicosanoate 4,7,10,13-Tetraoxa-16-azaeicosanoic acid, 20-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-17,20-dioxo-, 2,5-dioxo-1-pyrrolidinyl ester DBCO-PEG4-SPA DBCO-PEG4-NHS inhibit,Inhibitor,DBCO PEG4 NHS ester,DBCOPEG4NHS ester,DBCO-PEG-4-NHS ester,PROTAC Linkers DBCO-PEG4-NHS easer 1427004-19-0 peg ADC-Linkers