DBCO-PEG4-SE
- CAS No.
- 1427004-19-0
- Chemical Name:
- DBCO-PEG4-SE
- Synonyms
- DBCO-PEG4-SE;DBCO-PEG4-NHS;DBCO-PEG4-SPA;DBCO-PEG4-NHS easer;DBCO-PEG4-NHS ester;DBCO-CONH-PEG4-NHS ester;DBCO-PEG4-succinimidyl ester;Dibenzocyclooctyne-PEG4-N-hydroxysuccinimidyl ester;inhibit,Inhibitor,DBCO PEG4 NHS ester,DBCOPEG4NHS ester,DBCO-PEG-4-NHS ester,PROTAC Linkers;2,5-Dioxo-1-pyrrolidinyl 20-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-17,20-dioxo-4,7,10,13-tetraoxa-16-azaeicosanoate
- CBNumber:
- CB22984375
- Molecular Formula:
- C34H39N3O10
- Molecular Weight:
- 649.69
- MDL Number:
- MFCD26793797
- MOL File:
- 1427004-19-0.mol
Density | 1.33±0.1 g/cm3(Predicted) |
---|---|
storage temp. | -20°C |
solubility | Soluble in DMSO, DCM, DMF |
pka | 15.14±0.46(Predicted) |
form | gel or oil |
color | Colourless to yellow |
InChIKey | RRCXYKNJTKJNTD-UHFFFAOYSA-N |
SMILES | C(ON1C(=O)CCC1=O)(=O)CCOCCOCCOCCOCCNC(=O)CCC(N1CC2=CC=CC=C2C#CC2=CC=CC=C12)=O |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P261-P305+P351+P338 |
WGK Germany | 3 |
HS Code | 2942000090 |
DBCO-PEG4-SE price More Price(9)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 764019 | Dibenzocyclooctyne-PEG4-N-hydroxysuccinimidyl ester 95% | 1427004-19-0 | 1MG | $37 | 2023-06-20 | Buy |
Sigma-Aldrich | 764019 | Dibenzocyclooctyne-PEG4-N-hydroxysuccinimidyl ester 95% | 1427004-19-0 | 5MG | $118 | 2023-06-20 | Buy |
Sigma-Aldrich | 764019 | Dibenzocyclooctyne-PEG4-N-hydroxysuccinimidyl ester 95% | 1427004-19-0 | 50MG | $510 | 2023-06-20 | Buy |
TRC | D195020 | DBCO-PEG4-NHSEster | 1427004-19-0 | 1mg | $45 | 2021-12-16 | Buy |
Chem-Impex | 35051 | DBCO-PEG4-NHSester,95% 95% | 1427004-19-0 | 5MG | $56 | 2021-12-16 | Buy |
DBCO-PEG4-SE Chemical Properties,Uses,Production
Description
DBCO-PEG4-NHS Ester is a click chemistry PEG reagent containing NHS ester that is able to react specifically and efficiently with primary amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic condition to form a covalent bond. The hydrophilic PEG spacer arm improves water solubility and provides a long and flexible connection that minimizes steric hindrance involved with ligation. DBCO is commonly used for copper-free Click Chemistry reactions.
Uses
Succinimidyl ester (NHS, amine reactive) functionalized cyclooctyne derivative for incorporation of the cyclooctyne moiety into amine containing compounds or biomolecules. Cyclooctynes are useful in strain-promoted copper-free click chemistry cycloaddition reactions. This dibenzocyclooctyne will react with azide functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage.
Applications Include:
- Protein-peptide conjugates
- Antibody-enzyme or antibody-drug conjugates
- Protein or peptide-oligonucleotide conjugates
- Surface modification
DBCO-PEG4-SE Preparation Products And Raw materials
Raw materials
Preparation Products
DBCO-PEG4-SE Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Xian confluore Biological Technology Co., Ltd. | +86-15680926068 +86-15680926068 | 1924344760@confluore.cn | China | 2995 | 58 |
9i LLC | +18039569191 | MWan@NiNeiLab.com | United States | 418 | 58 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32957 | 60 |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10310 | 58 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 13503 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32165 | 58 |
Wuhan Borenpharm Co., Ltd | 027-65563561 18717150066 | 3207347307@qq.com | CHINA | 1238 | 58 |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10473 | 58 |
View Lastest Price from DBCO-PEG4-SE manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-11-19 | DBCO-PEG4-NHS ester
1427004-19-0
|
US $59.00-247.00 / mg | ≥98% | 10g | TargetMol Chemicals Inc. | |||
2024-03-20 | DBCO-PEG4-NHS ester
1427004-19-0
|
US $0.00 / mg | 50mg | >99.00% | 250 | Xian confluore Biological Technology Co., Ltd. |
- DBCO-PEG4-NHS ester
1427004-19-0
- US $59.00-247.00 / mg
- ≥98%
- TargetMol Chemicals Inc.
- DBCO-PEG4-NHS ester
1427004-19-0
- US $0.00 / mg
- >99.00%
- Xian confluore Biological Technology Co., Ltd.