DBCO-NHS Ester
- CAS No.
- 1353016-71-3
- Chemical Name:
- DBCO-NHS Ester
- Synonyms
- N-Succinimidyl 4-[(5-Aza-3,4:7,8-dibenzocyclooct-1-yne)-5-yl]-4-oxobutyrate;DBCO-NHS;DBCO-NHS ester;CAS_1353016-71-3;DBCO-NHS Ester (CCT-A133);DBCO-NHS ester, 10 mM in DMSO;DBCO-NHS Ester, ≥98% (CCT-1491);DBCO-NHS ester (DBCO NHS ester);Dibenzocycloctyne n-hydroxysuccinimide;4-[(5-aza-3，4:7，8-dibenzocyclooctan-1-yne)-5-yl]-4-oxobutyrate-n-succinimide
- CBNumber:
- CB23146567
- Molecular Formula:
- C23H18N2O5
- Molecular Weight:
- 402.4
- MDL Number:
- MFCD24386367
- MOL File:
- 1353016-71-3.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 29339900 |
DBCO-NHS Ester price More Price(16)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | D194965 | DBCO-NHSEster | 1353016-71-3 | 1mg | $50 | 2021-12-16 | Buy |
| Chem-Impex | 33411 | DBCO-NHSester,98%(HPLC) 98%(HPLC) | 1353016-71-3 | 5MG | $112 | 2021-12-16 | Buy |
| BroadPharm | BP-22231 | DBCO-NHS 97% | 1353016-71-3 | 50mg | $140 | 2021-12-16 | Buy |
| Chem-Impex | 33411 | DBCO-NHSester,98%(HPLC) 98%(HPLC) | 1353016-71-3 | 25MG | $212.8 | 2021-12-16 | Buy |
| ChemScene | CS-0021839 | DBCO-NHSester 99.22% | 1353016-71-3 | 100mg | $215 | 2021-12-16 | Buy |
DBCO-NHS Ester Chemical Properties,Uses,Production
Description
DBCO-NHS Ester is a very popular amine-reactive click chemistry reagent. It can be used to modify an amine-containing molecule in organic solvents (limited solubility in aqueous media). It reacts with primary amines such as the side chain of lysine residues or aminosilane-coated surfaces at neutral or slightly basic pH to form covalent bonds. The low mass weight will add minimal spacer to modified molecules. DBCO is commonly used for copper-free Click Chemistry reactions.
Uses
DBCO NHS ester contains an NHS carbonate group and a DBCO group. The spacer contains a photocleavable nitrobenzyloxyl group, which can be efficiently cleaved under UV to release the conjugated molecules. DBCO on the other hand readily react with azide bearing biomolecule through a copper-free click reaction instantly and in high yield.
DBCO-NHS Ester is a very popular amine-reactive click chemistry reagent. It can be used to modify an amine-containing molecule in organic solvents (limited solubility in aqueous media). It reacts with primary amines such as the side chain of lysine residues or aminosilane-coated surfaces at neutral or slightly basic pH to form covalent bonds. The low mass weight will add minimal spacer to modified molecules. DBCO is commonly used for copper-free Click Chemistry reactions.
Uses
DBCO-NHS Ester is a derivative of DBCO (Dibenzylcyclooctyne), used in Cu-free click chemistry. It useful in strain-promoted copper-free azide-alkyne cycloaddition reactions. Used in DNA-Assisted protein analysis such as proximity ligation and extention assays. Intracellular Imaging.
IC 50
Cleavable Linker
DBCO-NHS Ester Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
DBCO-NHS Ester Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 9i LLC | +18039569191 | MWan@NiNeiLab.com | United States | 418 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 19825 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 12162 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32159 | 58 |
| Wuhan Borenpharm Co., Ltd | 027-65563561 18717150066 | 3207347307@qq.com | CHINA | 1238 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30231 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6312 | 58 |
| GL Biochem (Shanghai) Ltd. | +86-021-61263370 +86-18901917034 | CHINA | 3904 | 58 |
| Supplier | Advantage |
|---|---|
| 9i LLC | 58 |
| ATK CHEMICAL COMPANY LIMITED | 60 |
| Accela ChemBio Inc. | 58 |
| BOC Sciences | 58 |
| Zhengzhou Alfa Chemical Co.,Ltd | 58 |
| TargetMol Chemicals Inc. | 58 |
| Wuhan Borenpharm Co., Ltd | 58 |
| Career Henan Chemica Co | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 58 |
| GL Biochem (Shanghai) Ltd. | 58 |
View Lastest Price from DBCO-NHS Ester manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-19 | DBCO-NHS ester
1353016-71-3
|
US $31.00-85.00 / mg | 98.02% | 10g | TargetMol Chemicals Inc. | ||
 |
2024-03-20 | DBCO-NHS ester
1353016-71-3
|
US $0.00 / mg | 100mg | >99.00% | 1g | Xian confluore Biological Technology Co., Ltd. |
-
- DBCO-NHS ester
1353016-71-3
- US $31.00-85.00 / mg
- 98.02%
- TargetMol Chemicals Inc.
-
- DBCO-NHS ester
1353016-71-3
- US $0.00 / mg
- >99.00%
- Xian confluore Biological Technology Co., Ltd.