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Azadibenzocyclooctyne-Biotin conjugate

Azadibenzocyclooctyne-Biotin conjugate Structure
Azadibenzocyclooctyne-Biotin conjugate structure
CAS No.
1418217-95-4
Chemical Name:
Azadibenzocyclooctyne-Biotin conjugate
Synonyms
DBCO-Biotin;DBCO-(CH2)2-NH2-BIOTIN;Azadibenzocyclooctyne-Biotin conjugate;DBCO-Biotin,Azadibenzocyclooctyne-Biotin conjugate;(3AS,4S,6aR)-N-[3-(11,12-Didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl]hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide;1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[3-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl]hexahydro-2-oxo-, (3aS,4S,6aR)-
CBNumber:
CB63309380
Molecular Formula:
C28H30N4O3S
Molecular Weight:
502.63
MDL Number:
MFCD22380751
MOL File:
1418217-95-4.mol
Last updated:2025-04-18 09:51:20
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Azadibenzocyclooctyne-Biotin conjugate Properties

Boiling point 905.9±65.0 °C(Predicted)
Density 1.35±0.1 g/cm3(Predicted)
pka 13.90±0.40(Predicted)
form Solid
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338

Azadibenzocyclooctyne-Biotin conjugate price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Iris Biotech GmbH LS-4270 Biotin-DBCO 1418217-95-4 100mg $810 2021-12-16 Buy
Iris Biotech GmbH LS-4270 Biotin-DBCO 1418217-95-4 250mg $1620 2021-12-16 Buy
DC Chemicals DC21887 DBCO-Biotin >98% 1418217-95-4 250mg $1700 2021-12-16 Buy
DC Chemicals DC21887 DBCO-Biotin >98% 1418217-95-4 1g $3400 2021-12-16 Buy
purepeg 288702 DBCO-Biotin min.95% 1418217-95-4 100mg $650 2021-12-16 Buy
Product number Packaging Price Buy
LS-4270 100mg $810 Buy
LS-4270 250mg $1620 Buy
DC21887 250mg $1700 Buy
DC21887 1g $3400 Buy
288702 100mg $650 Buy

Azadibenzocyclooctyne-Biotin conjugate Chemical Properties,Uses,Production

Uses

DBCO-Biotin is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-Biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

IC 50

Alkyl-Chain

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Azadibenzocyclooctyne-Biotin conjugate Preparation Products And Raw materials

Raw materials

Preparation Products

Azadibenzocyclooctyne-Biotin conjugate Suppliers

Global( 32)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32190 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6312 58
Alfa Chemistry 		Info@alfa-chemistry.com United States 24072 58
TargetMol Chemicals Inc. 		support@targetmol.com United States 38633 58
Xian confluore Biological Technology Co., Ltd. 		+86-15680926068 +86-15680926068 1924344760@confluore.cn China 2996 58
Shanghai Macklin Biochemical Co.,Ltd. 15221275939 shenlinxing@macklin.cn China 15874 55
Shanghai Send Pharmaceutical Technology Co., Ltd. 021-58088081 3252066219 sale1@shsendpharm.com China 3095 55
ATK CHEMICAL COMPANY LIMITED 021-51619050 13301662590 mandy@atkchemical.com China 9109 55
Xi'an Confluore Biological Technology Co., Ltd. +86-156-80926068 +86-15680926068 1924344760@qq.com China 4838 58
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
TargetMol Chemicals Inc. 		58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		58
Alfa Chemistry 		58
TargetMol Chemicals Inc. 		58
Xian confluore Biological Technology Co., Ltd. 		58
Shanghai Macklin Biochemical Co.,Ltd. 55
Shanghai Send Pharmaceutical Technology Co., Ltd. 55
ATK CHEMICAL COMPANY LIMITED 55
Xi'an Confluore Biological Technology Co., Ltd. 58

View Lastest Price from Azadibenzocyclooctyne-Biotin conjugate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
DBCO-Biotin pictures 2025-04-27 DBCO-Biotin
1418217-95-4
 US $45.00-163.00 / mg 10g TargetMol Chemicals Inc.
DBCO-Biotin pictures 2024-03-20 DBCO-Biotin
1418217-95-4
 US $0.00 / mg 25mg >99.00% 100 Xian confluore Biological Technology Co., Ltd.
  • DBCO-Biotin pictures
  • DBCO-Biotin
    1418217-95-4
  • US $45.00-163.00 / mg
  • TargetMol Chemicals Inc.
  • DBCO-Biotin pictures
  • DBCO-Biotin
    1418217-95-4
  • US $0.00 / mg
  • >99.00%
  • Xian confluore Biological Technology Co., Ltd.

1418217-95-4(Azadibenzocyclooctyne-Biotin conjugate)Related Search:

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DBCO-(CH2)3-Acid

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Azadibenzocyclooctyne-Biotin conjugate DBCO-(CH2)2-NH2-BIOTIN DBCO-Biotin,Azadibenzocyclooctyne-Biotin conjugate 1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[3-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl]hexahydro-2-oxo-, (3aS,4S,6aR)- (3AS,4S,6aR)-N-[3-(11,12-Didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl]hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide DBCO-Biotin 1418217-95-4