Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>(2S,3S)-N-((S)-1-(4-(5-(2-cyclopentylethyl)-1,2,4-oxadiazol-3-yl)phenyl)ethyl)-3-hydroxypyrrolidine-2-carboxamide

(2S,3S)-N-((S)-1-(4-(5-(2-cyclopentylethyl)-1,2,4-oxadiazol-3-yl)phenyl)ethyl)-3-hydroxypyrrolidine-2-carboxamide

(2S,3S)-N-((S)-1-(4-(5-(2-cyclopentylethyl)-1,2,4-oxadiazol-3-yl)phenyl)ethyl)-3-hydroxypyrrolidine-2-carboxamide Structure
(2S,3S)-N-((S)-1-(4-(5-(2-cyclopentylethyl)-1,2,4-oxadiazol-3-yl)phenyl)ethyl)-3-hydroxypyrrolidine-2-carboxamide structure
CAS No.
1218816-71-7
Chemical Name:
(2S,3S)-N-((S)-1-(4-(5-(2-cyclopentylethyl)-1,2,4-oxadiazol-3-yl)phenyl)ethyl)-3-hydroxypyrrolidine-2-carboxamide
Synonyms
SK1-IN-1;SK1 inhibitor 1;SK-1-IN-1,SK1IN1,SK1 IN 1;(2S,3S)-N-((S)-1-(4-(5-(2-cyclopentylethyl)-1,2,4-oxadiazol-3-yl)phenyl)ethyl)-3-hydroxypyrrolidine-2-carboxamide;2-Pyrrolidinecarboxamide, N-[(1S)-1-[4-[5-(2-cyclopentylethyl)-1,2,4-oxadiazol-3-yl]phenyl]ethyl]-3-hydroxy-, (2S,3S)-
CBNumber:
CB23039551
Molecular Formula:
C22H30N4O3
Molecular Weight:
398.5
MDL Number:
MFCD31382196
MOL File:
1218816-71-7.mol
Last updated:2024-10-23 13:36:13
Request For Quotation

(2S,3S)-N-((S)-1-(4-(5-(2-cyclopentylethyl)-1,2,4-oxadiazol-3-yl)phenyl)ethyl)-3-hydroxypyrrolidine-2-carboxamide Properties

Density 1.200±0.06 g/cm3(Predicted)
pka 14.20±0.40(Predicted)
form Solid
color Light yellow to yellow

(2S,3S)-N-((S)-1-(4-(5-(2-cyclopentylethyl)-1,2,4-oxadiazol-3-yl)phenyl)ethyl)-3-hydroxypyrrolidine-2-carboxamide price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-6936 SK1-IN-1 98.75% 1218816-71-7 1mg $180 2021-12-16 Buy
ChemScene CS-6936 SK1-IN-1 98.75% 1218816-71-7 5mg $420 2021-12-16 Buy
ChemScene CS-6936 SK1-IN-1 98.75% 1218816-71-7 10mg $720 2021-12-16 Buy
ChemScene CS-6936 SK1-IN-1 98.75% 1218816-71-7 25mg $1440 2021-12-16 Buy
ChemScene CS-6936 SK1-IN-1 98.75% 1218816-71-7 50mg $2280 2021-12-16 Buy
Product number Packaging Price Buy
CS-6936 1mg $180 Buy
CS-6936 5mg $420 Buy
CS-6936 10mg $720 Buy
CS-6936 25mg $1440 Buy
CS-6936 50mg $2280 Buy

(2S,3S)-N-((S)-1-(4-(5-(2-cyclopentylethyl)-1,2,4-oxadiazol-3-yl)phenyl)ethyl)-3-hydroxypyrrolidine-2-carboxamide Chemical Properties,Uses,Production

Biological Activity

SK1-IN-1 is a potent sphingosine kinase 1 (SPHK1) inhibitor with IC50 of 58 nM.

in vivo

SK1-IN-1 demonstrates significant improvement in the intrinsic clearance, particularly against human liver microsomes. It is selected for rat PK studies and demonstrates modest in oral bioavailability with acceptable half-lives in blood circulation demonstrates .

target

IC50: 58 nM (SPHK1)

(2S,3S)-N-((S)-1-(4-(5-(2-cyclopentylethyl)-1,2,4-oxadiazol-3-yl)phenyl)ethyl)-3-hydroxypyrrolidine-2-carboxamide Preparation Products And Raw materials

Raw materials

Preparation Products

(2S,3S)-N-((S)-1-(4-(5-(2-cyclopentylethyl)-1,2,4-oxadiazol-3-yl)phenyl)ethyl)-3-hydroxypyrrolidine-2-carboxamide Suppliers

Global( 21)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32024 58
TargetMol Chemicals Inc. 		support@targetmol.com United States 38463 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9806 58
Beijing Solarbio Science & Tecnology Co., Ltd. 010-50973130 4009686088 3193328036@qq.com China 29786 68
Angel Pharmatech, Ltd. 17317130613 3358272972@qq.com China 3249 58
Fan De(Beijing) Biotechnology Co., Ltd. 15911056312 liming@bio-fount.com China 9729 58
BOC Sciences -- info@bocsci.com USA 0 65
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11217 58
Shanghai Zeye Biotechnology Co., Ltd. 021-61998551 13122364865 sale1@shzysw.net China 9772 58
Shanghai hongqu biomedical technology co. LTD 88888888888 hongquchem@qq.com China 5132 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
TargetMol Chemicals Inc. 		58
Shanghai EFE Biological Technology Co., Ltd. 58
Beijing Solarbio Science & Tecnology Co., Ltd. 68
Angel Pharmatech, Ltd. 58
Fan De(Beijing) Biotechnology Co., Ltd. 58
BOC Sciences 65
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Shanghai Zeye Biotechnology Co., Ltd. 58
Shanghai hongqu biomedical technology co. LTD 58

View Lastest Price from (2S,3S)-N-((S)-1-(4-(5-(2-cyclopentylethyl)-1,2,4-oxadiazol-3-yl)phenyl)ethyl)-3-hydroxypyrrolidine-2-carboxamide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
SK1-IN-1 pictures 2024-10-24 SK1-IN-1
1218816-71-7
 US $216.00 / mg 98.72% 10g TargetMol Chemicals Inc.
  • SK1-IN-1 pictures
  • SK1-IN-1
    1218816-71-7
  • US $216.00 / mg
  • 98.72%
  • TargetMol Chemicals Inc.
(2S,3S)-N-((S)-1-(4-(5-(2-cyclopentylethyl)-1,2,4-oxadiazol-3-yl)phenyl)ethyl)-3-hydroxypyrrolidine-2-carboxamide SK1-IN-1 2-Pyrrolidinecarboxamide, N-[(1S)-1-[4-[5-(2-cyclopentylethyl)-1,2,4-oxadiazol-3-yl]phenyl]ethyl]-3-hydroxy-, (2S,3S)- SK1 inhibitor 1 SK-1-IN-1,SK1IN1,SK1 IN 1 1218816-71-7