ChemicalBook >> CAS DataBase List >>9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-OIC ACID, 1,15-LACTONE

9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-OIC ACID, 1,15-LACTONE

9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-OIC ACID, 1,15-LACTONE structure

CAS No.: 55314-49-3

Chemical Name:: 9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-OIC ACID, 1,15-LACTONE

Synonyms: u47473;13e,15s)-1-alph;pgf2-alpha1,15-lactone;Prostaglandin F2α 1,15-lactone;PROSTAGLANDIN F2ALPHA 1,15-LACTONE;prosta-5,13-dien-1-oicacid,9,11,15-trihydroxy-,lambda-lactone,(5z,9-alpha,1;9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-OIC ACID, 1,15-LACTONE;(1R,3Z,10S,11E,13R,14R,16S)-14,16-dihydroxy-10-pentyl-9-oxabicyclo[11.3.0]hexadeca-3,11-dien-8-one

CBNumber:: CB2305970

Molecular Formula:: C20H32O4

Molecular Weight:: 336.47

MDL Number:: MFCD00065774

MOL File:: 55314-49-3.mol

Last updated:2025-04-17 18:22:24

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9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-OIC ACID, 1,15-LACTONE Properties

storage temp.	Store at -20°C
solubility	DMF: >20.4 mg/ml; DMSO: >10 mg/ml; Ethanol: >105 mg/ml; Ethanol:PBS (30:70): 8 mg/ml; PBS (pH 7.2): <50 ug/ml
form	A crystalline solid

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07,GHS08

Signal word

Danger

Hazard statements

H302-H360

Precautionary statements

P201-P202-P264-P270-P280-P301+P312-P330-P308+P313-P405-P501

NFPA 704

	0
2		0

9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-OIC ACID, 1,15-LACTONE price More Price(4)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	16120	Prostaglandin F2α 1,15-lactone ≥99%	55314-49-3	1mg	$87	2024-03-01	Buy
Cayman Chemical	16120	Prostaglandin F2α 1,15-lactone ≥99%	55314-49-3	5mg	$384	2024-03-01	Buy
Cayman Chemical	16120	Prostaglandin F2α 1,15-lactone ≥99%	55314-49-3	10mg	$680	2024-03-01	Buy
AK Scientific	1548AH	9alpha,11alpha,15S-Trihydroxy-prosta-5Z,13E-dien-1-oicacid,1,15-lactone	55314-49-3	1mg	$194	2021-12-16	Buy

Product number	Packaging	Price	Buy
16120	1mg	$87	Buy
16120	5mg	$384	Buy
16120	10mg	$680	Buy
1548AH	1mg	$194	Buy

9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-OIC ACID, 1,15-LACTONE Chemical Properties,Uses,Production

Description

PGF_2α 1,15-lactone is a lipid-soluble internal ester of PGF_2α. Hydrolysis of the lactone readily produces free PGF_2α in plasma. In rhesus monkeys, a total dose of 15 mg of PGF_2α 1,15-lactone terminates early pregnancy, whereas PGF_2α is ineffective.

Uses

PGF2α 1,15-lactone (Prostaglandin F2α 1,15-lactone) is a lipid-soluble internal ester of PGF2α. PGF2α 1,15-lactone decreases menstrual cycle lengths in non-pregnant rhesus monkeys. PGF2α 1,15-lactone terminates early pregnancy in the monkey[1].

in vivo

PGF2α 1,15-lactone (5 mg for i.v.; 3 mg for intramuscularly) terminates early pregnancy in the monkey^[1].

Animal Model:	Rhesus monkey (trimester pregnant)^[1]
Dosage:	5 mg for i.v.; 3 mg for intramuscularly
Administration:	IV on days 30 and 31, 31 and 32, or 33 and 34; Intramuscularly on days 29 and 30, 30 and 31, or 33 and 34
Result:	Aborted between 36 and 48 hr after treatment, Within 10 minutes after treatment there was a significant increase in uterine tone and frequency of contractions.

References

[1] Spilman CH, et al. Effects of PGF2alpha and PGF2alpha, 1-15 lactone on the corpus luteum and on early pregnancy in the rhesus monkey. Prostaglandins. 1977 Sep;14(3):477-88. DOI:10.1016/0090-6980(77)90262-3

9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-OIC ACID, 1,15-LACTONE Preparation Products And Raw materials

Raw materials

Prosta-5,13-dien-1-oic acid, 9,11-[(butylborylene)bis(oxy)]-15-hydroxy-, λ-lactone, (5Z,9α,11α,13E,15S)- (9CI)

Preparation Products

9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-OIC ACID, 1,15-LACTONE Suppliers

Global( 21)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32159	58
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6777	58
Hangzhou Synstar pharmaceutical Technology CO.,Ltd	0571-85361029	synstar518@163.com	China	1990	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24641	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	11973	58
Cayman Chemical Company	800-3649897	Caymanname@qq.com	China	21645	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
Shanghai Hongye Biotechnology Co. Ltd	58
Hangzhou Synstar pharmaceutical Technology CO.,Ltd	58
TargetMol Chemicals Inc.	58
Shanghai Yifei Biotechnology Co. , Ltd.	58
Cayman Chemical Company	58

View Lastest Price from 9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-OIC ACID, 1,15-LACTONE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-10-24	Prostaglandin F2α 1,15-lactone 55314-49-3	US $218.00-1700.00 / mg			10g	TargetMol Chemicals Inc.

Prostaglandin F2α 1,15-lactone
55314-49-3
US $218.00-1700.00 / mg
TargetMol Chemicals Inc.

55314-49-3(9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-OIC ACID, 1,15-LACTONE)Related Search:

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1of4

pgf2-alpha1,15-lactone prosta-5,13-dien-1-oicacid,9,11,15-trihydroxy-,lambda-lactone,(5z,9-alpha,1 u47473 Prostaglandin F2α 1,15-lactone 9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-OIC ACID, 1,15-LACTONE PROSTAGLANDIN F2ALPHA 1,15-LACTONE 13e,15s)-1-alph (1R,3Z,10S,11E,13R,14R,16S)-14,16-dihydroxy-10-pentyl-9-oxabicyclo[11.3.0]hexadeca-3,11-dien-8-one 55314-49-3