Verbascoside | 61276-17-3

Verbascoside Properties

Melting point	232℃
Boiling point	908.8±65.0 °C(Predicted)
Density	1.60±0.1 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
solubility	DMSO (Slightly), Ethyl Acetate (Very Slightly), Methanol (Slightly)
pka	9.31±0.10(Predicted)
form	Solid
color	White to Pale Yellow
Stability	Hygroscopic
InChIKey	FBSKJMQYURKNSU-ZLSOWSIRSA-N
LogP	0.077 (est)
CAS DataBase Reference	61276-17-3(CAS DataBase Reference)
FDA UNII	3TGX09BD5B

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P280-P301+P312-P302+P352-P305+P351+P338
Safety Statements	24/25
WGK Germany	2
RTECS	LZ5786000
HS Code	29389090
Toxicity	LD50 oral in rat: > 5gm/kg

Verbascoside price More Price(52)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	1711455	Verbascoside United States Pharmacopeia (USP) Reference Standard	61276-17-3	15mg	$539	2024-03-01	Buy
Sigma-Aldrich	00820580	Verbascoside primary pharmaceutical reference standard	61276-17-3	10mg	$570	2024-03-01	Buy
Sigma-Aldrich	PHL89289	Verbascoside phyproof? Reference Substance	61276-17-3	10MG	$435	2023-01-07	Buy
TCI Chemical	V0153	Verbascoside >97.0%(HPLC)	61276-17-3	10mg	$141	2024-03-01	Buy
TCI Chemical	V0153	Verbascoside >97.0%(HPLC)	61276-17-3	50mg	$494	2024-03-01	Buy

Product number	Packaging	Price	Buy
1711455	15mg	$539	Buy
00820580	10mg	$570	Buy
PHL89289	10MG	$435	Buy
V0153	10mg	$141	Buy
V0153	50mg	$494	Buy

Verbascoside Chemical Properties,Uses,Production

Description

Verbascoside is isolated from Lantana camara, acts as an ATP-competitive inhibitor of PKC, with an IC50 of 25 µM, and has antitumor, anti-inflammatory and antineuropathic pain activity.

Natural occurrences

Verbascoside can be found in species in all the families of the order Lamiales (syn. Scrophulariales). Only two examples are known from outside the order,in the clade Asterids.

Mechanism of action

It is known, that amyloid fibrils accumulation in cerebral can easily lead to neurodegenerative disorders. Acteoside has been reported to inhibit Aβ42 aggregation by activating nuclear translocation of the transcription factor NF-E2-related factor 2 (Nrf2), increasing heme oxygenase-1 (HO-1) expression. It has also been shown that acteoside could decrease nitric oxide synthase (NOS) activity and caspase-3 expression.

Chemical Properties

White solid

Uses

Verbascoside is an agent producing effects on anti-GBM nephritis in rats. Effective agent against glomerulonephritis. Phenolic anti-oxidant agent.

Definition

ChEBI: Acteoside is a glycoside that is the alpha-L-rhamnosyl-(1->3)-beta-D-glucoside of hydroxytyrosol in which the hydroxy group at position 4 of the glucopyranosyl moiety has undergone esterification by formal condensation with trans-caffeic acid. It has a role as a neuroprotective agent, an antileishmanial agent, an anti-inflammatory agent, a plant metabolite and an antibacterial agent. It is a cinnamate ester, a disaccharide derivative, a member of catechols, a polyphenol and a glycoside. It is functionally related to a hydroxytyrosol and a trans-caffeic acid.

Enzyme inhibitor

This plant glycoside and antioxidant (FW = 624.60 g/mol; CAS 61276-173), also known as verbascoside, inhibits TNFa-mediated apoptosis in LPSstimulated macrophages as well as 1-methyl-4-phenylpyridiniuminduced apoptosis in cerebellar granule neurons. It also inhibits proliferation of human promyelocytic HL-60 leukemia cells by inducing cell cycle arrest at the G0/G1 phase, followed by differentiation into monocytes. Acteoside inhibits PMA-induced invasion and migration of human fibrosarcoma cells by Ca2+-dependent CaMK/ERK and JNK/NFκB-signaling pathways. Acteoside thus shows the potential as antimetastatic agent. Another intriguing finding is that acteoside inhibits amyloid-β aggregation. Target(s): aldose reductase; protein kinase C; integrase, HIV-1; peptidyl-dipeptidase A, or angiotensin-converting enzyme; tyrosinase, or monophenol monooxygenase; 5-lipoxygenase, or arachidonate 5-lipoxygenase.

Verbascoside Preparation Products And Raw materials

Raw materials

Preparation Products

Verbascoside Suppliers

Global( 292)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21688	55
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	fandachem@gmail.com	China	9341	55
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3620	58
Chengdu GLP biotechnology Co Ltd	028-87075086 13350802083	scglp@glp-china.com	CHINA	1824	58
Chengdu Biopurify Phytochemicals Ltd.	+8618080483897	sales@biopurify.com	China	3424	58
Nanjing Dolon Biotechnology Co.,Ltd.	18905173768	sales@dolonchem.com	CHINA	2972	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Xi'an Kono chem co., Ltd.,	029-86107037 13289246953	info@konochemical.com	China	2995	58
NanJing Spring & Autumn Biological Engineering CO., LTD.	+8613815430202	sale02@cqherb.com	CHINA	376	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58

Supplier	Advantage
Henan Tianfu Chemical Co.,Ltd.	55
Hangzhou FandaChem Co.,Ltd.	55
Shanghai Zheyan Biotech Co., Ltd.	58
Chengdu GLP biotechnology Co Ltd	58
Chengdu Biopurify Phytochemicals Ltd.	58
Nanjing Dolon Biotechnology Co.,Ltd.	58
Hubei Jusheng Technology Co.,Ltd.	58
Xi'an Kono chem co., Ltd.,	58
NanJing Spring & Autumn Biological Engineering CO., LTD.	58
BOC Sciences	58

View Lastest Price from Verbascoside manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-06-03	Cistanche Deserticola Extract Acteoside; Verbascoside; Kusaginin 61276-17-3	US $0.00-0.00 / kg	1kg	1-98%	1000kg	Changsha Staherb Natural Ingredients Co., Ltd.
2024-06-03	Cistanche Deserticola Extract Acteoside; Verbascoside; Kusaginin 61276-17-3	US $0.00-0.00 / kg	1kg	1-98%	1000kg	Changsha Staherb Natural Ingredients Co., Ltd.
2024-06-03	Desertliving Cistanche Extract 61276-17-3	US $0.00 / Kg/Bag	2Kg/Bag	Echinacoside 80%	20 tons	Sinoway Industrial co., ltd.

Cistanche Deserticola Extract Acteoside; Verbascoside; Kusaginin
61276-17-3
US $0.00-0.00 / kg
1-98%
Changsha Staherb Natural Ingredients Co., Ltd.

Cistanche Deserticola Extract Acteoside; Verbascoside; Kusaginin
61276-17-3
US $0.00-0.00 / kg
1-98%
Changsha Staherb Natural Ingredients Co., Ltd.

Desertliving Cistanche Extract
61276-17-3
US $0.00 / Kg/Bag
Echinacoside 80%
Sinoway Industrial co., ltd.

Verbascoside Spectrum

Verbascoside(61276-17-3)¹HNMR

61276-17-3(Verbascoside)Related Search:

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Isoacteoside CAMPNEOSIDE I MARTYNOSIDE

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glucopyranoside,2-(3,4-dihydroxyphenyl)ethyl3-o-(6-deoxy-alpha-l-mannopyranos ACTEOSIDE :B-D-GLUCOPYRANOSIDE, 2-(3,4-DIHYDROXYPHENYL)ETHYL 3-O-(6-DEOXY-A-L-MANNOPYRANOSYL)-,4-[3-(3,4-DIHYDROXYPHENYL)-2-PROPENOATE],(E)-, Extract from Verbena minutiflora (B864379) [(2R,3R,4R,5R,6R)-6-[2-(3,4-Dihydroxyphenyl)ethoxy]-5-hydroxy-2-(hydroxymethyl)-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate VERBASCOSIDE WITH HPLC 2-(3,4-Dihydroxyphenyl)ethyl 3-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside 4-[(E)-3-(3,4-dihydroxyphenyl)propenoate] 3,4-Dihydroxyphenethyl alcohol acteoside Verbacoside Acteoside(Verbascoside) Distinctive PhytosteM Lilac Verbascoside ,98% NSC 603831 Russetinol StereosperMin TJC 160 Verbascoside(Acteoside) Verbascoside, froM Cistanche deserticola Y.C.Ma VERBASCOSIDE B-D-GLUCOPYRANOSIDE, 2-(3,4-DIHYDROXYPHENYL)ETHYL 3-O-(6-DEOXY-ALPHA-L-MANNOPYRANOSYL)-,4-[3-(3,4-DIHYDROXYPHENYL)-2-PROPENOATE],(E)- 4-(3-(3,4-dihydroxyphenyl)-2-propenoate),(e)-beta-d-yl) Verbascoside [(2R,3R,4R,5R,6R)-6-[2-(3,4-Dihydroxyphenyl)ethoxy]-5-hydroxy-2-(hydroxymethyl)-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate β-D-Glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl 3-O-(6-deoxy-α-L-mannopyranosyl)-, 4-[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoate] Nano Liposomal Acteoside Verbascoside, 98%, from Cistanche deserticola Y.C.Ma Acteoside Kusaginin 61276-17-3 Kusagi Acteoside Standard 2-(3,4-Dihydroxyphenyl)ethyl 3-O-(6-Deoxy-alpha-L-mannopyranosyl)-4-O-[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoyl]-beta-D-glucopyranoside Verbascoside USP/EP/BP Acetoside ISOVERBASCOSIDE ACTEOSIDE Cistanche Deserticola Extract Acteoside KUSAGININ (2R,3R,4R,5R,6R)-6-(3,4-Dihydroxyphenethoxy)-5-hydroxy-2-(hydroxymethyl)-4-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-3-yl (E)-3-(3,4-dihydroxyphenyl)acrylate Verbascoside (15 mg) 61276-17-3 reference standards from Chinese medicinal herbs (TCM). standardized herbal extract chemical reagent pharmaceutical intermediate phytochemical Miscellaneous Natural Products