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ChemicalBook >> CAS DataBase List >>N-(2-Aminophenyl)-4-[1-[2-(3-thienyl)ethyl]-1H-1,2,3-triazol-4-yl]benzamide

N-(2-Aminophenyl)-4-[1-[2-(3-thienyl)ethyl]-1H-1,2,3-triazol-4-yl]benzamide

N-(2-Aminophenyl)-4-[1-[2-(3-thienyl)ethyl]-1H-1,2,3-triazol-4-yl]benzamide Structure
N-(2-Aminophenyl)-4-[1-[2-(3-thienyl)ethyl]-1H-1,2,3-triazol-4-yl]benzamide structure
CAS No.
1451042-18-4
Chemical Name:
N-(2-Aminophenyl)-4-[1-[2-(3-thienyl)ethyl]-1H-1,2,3-triazol-4-yl]benzamide
Synonyms
T247;HDAC3INT247;HDAC3-IN-T247;HDAC3 IN T247;HDAC3 inhibitor T247;HDAC3 inhibitor-T247;N-(2-Aminophenyl)-4-[1-[2-(3-thienyl)ethyl]-1H-1,2,3-triazol-4-yl]benzamide;Benzamide, N-(2-aminophenyl)-4-[1-[2-(3-thienyl)ethyl]-1H-1,2,3-triazol-4-yl]-;N-(2-Aminophenyl)-4-(1-(2-(thiophen-3-yl)ethyl)-1H-1,2,3-triazol-4-yl)benzamide;N-(2-Aminophenyl)-4-[1-[2-(3-thienyl)ethyl]-1H-1,2,3-triazol-4-yl]benzamide
CBNumber:
CB23069651
Molecular Formula:
C21H19N5OS
Molecular Weight:
389.47
MDL Number:
MFCD29089340
MOL File:
1451042-18-4.mol
Last updated:2025-04-18 09:51:55
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N-(2-Aminophenyl)-4-[1-[2-(3-thienyl)ethyl]-1H-1,2,3-triazol-4-yl]benzamide Properties

Melting point 236 °C
Density 1.34±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
pka 12.39±0.70(Predicted)
form powder to crystal
color White to Yellow to Orange

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
HS Code  2934.99.4400
NFPA 704
0
2 0

N-(2-Aminophenyl)-4-[1-[2-(3-thienyl)ethyl]-1H-1,2,3-triazol-4-yl]benzamide price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical A2897 N-(2-Aminophenyl)-4-[1-[2-(3-thienyl)ethyl]-1H-1,2,3-triazol-4-yl]benzamide >95.0%(HPLC) 1451042-18-4 5mg $167 2024-03-01 Buy
AK Scientific 2893DV N-(2-Aminophenyl)-4-[1-[2-(3-thienyl)ethyl]-1H-1,2,3-triazol-4-yl]benzamide 1451042-18-4 5mg $291 2021-12-16 Buy
Product number Packaging Price Buy
A2897 5mg $167 Buy
2893DV 5mg $291 Buy

N-(2-Aminophenyl)-4-[1-[2-(3-thienyl)ethyl]-1H-1,2,3-triazol-4-yl]benzamide Chemical Properties,Uses,Production

Uses

HDAC3-IN-T247 is a potent and selective HDAC3 (histone deacetylase 3) inhibitor, with an IC50 of 0.24 μM. HDAC3-IN-T247 induces a selective increase of NF-κB acetylation in HCT116 cells. HDAC3-IN-T247 shows anticancer and antiviral activity. HDAC3-IN-T247 inhibits growth of cancer cells, and activates HIV gene expression in latent HIV-infected cells[1].

IC 50

HDAC3: 0.24 μM (IC50); HDAC1: 19 μM (IC50); HDAC4: >100 μM (IC50); HDAC6: >100 μM (IC50); HDAC8: >100 μM (IC50)

References

[1] Suzuki T, et al. Identification of highly selective and potent histone deacetylase 3 inhibitors using click chemistry-based combinatorial fragment assembly. PLoS One. 2013 Jul 16;8(7):e68669. DOI:10.1371/journal.pone.0068669

N-(2-Aminophenyl)-4-[1-[2-(3-thienyl)ethyl]-1H-1,2,3-triazol-4-yl]benzamide Preparation Products And Raw materials

Raw materials

Preparation Products

N-(2-Aminophenyl)-4-[1-[2-(3-thienyl)ethyl]-1H-1,2,3-triazol-4-yl]benzamide Suppliers

Global( 18)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+17819995354 marketing@targetmol.com United States 32292 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6312 58
Aladdin Scientific 		tp@aladdinsci.com United States 52924 58
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24529 81
TOKYO CHEMICAL INDUSTRY CO., LTD. 03-36680489 Sales-JP@TCIchemicals.com Japan 28387 80
TCI Europe 320-37350700 sales@tcieurope.eu Europe 23671 75
TCI AMERICA 800-4238616 sales@tciamerica.com Americas 23653 75
Shanghai XR Chemical Technology Co., Ltd. 021-31007982 18019432809 info@xrpharma.com China 673 55
Shandong Ono Chemical Co., Ltd. 0539-6362799 20） China 9998 58
Energy Chemical 021-58432009 400-005-6266 marketing1@energy-chemical.com China 44813 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		58
Aladdin Scientific 		58
TCI (Shanghai) Development Co., Ltd. 81
TOKYO CHEMICAL INDUSTRY CO., LTD. 80
TCI Europe 75
TCI AMERICA 75
Shanghai XR Chemical Technology Co., Ltd. 55
Shandong Ono Chemical Co., Ltd. 58
Energy Chemical 58
N-(2-Aminophenyl)-4-[1-[2-(3-thienyl)ethyl]-1H-1,2,3-triazol-4-yl]benzamide N-(2-Aminophenyl)-4-[1-[2-(3-thienyl)ethyl]-1H-1,2,3-triazol-4-yl]benzamide HDAC3-IN-T247 HDAC3INT247 HDAC3 inhibitor-T247 HDAC3 inhibitor T247 HDAC3 IN T247 T247 Benzamide, N-(2-aminophenyl)-4-[1-[2-(3-thienyl)ethyl]-1H-1,2,3-triazol-4-yl]- N-(2-Aminophenyl)-4-(1-(2-(thiophen-3-yl)ethyl)-1H-1,2,3-triazol-4-yl)benzamide 1451042-18-4