Crocin
- CAS No.
- 42553-65-1
- Chemical Name:
- Crocin
- Synonyms
- GARDENIN;Crocin A;Crocins;Crocin 1;CROCETIN DIGENTIOBIOSYL ESTER;CROCIN;Crocin-Ⅰ;α-Crocin;CCRIS 7705;Crocin ,98%
- CBNumber:
- CB2311935
- Molecular Formula:
- C44H64O24
- Molecular Weight:
- 976.97
- MDL Number:
- MFCD00017495
- MOL File:
- 42553-65-1.mol
- MSDS File:
- SDS
Melting point | 186° (effervescence) |
---|---|
Boiling point | 1169.0±65.0 °C(Predicted) |
Density | 1.54±0.1 g/cm3(Predicted) |
storage temp. | 2-8°C |
solubility | DMSO (Slightly, Heated), Methanol (Very Slightly, Sonicated) |
form | Powder |
pka | 12.20±0.70(Predicted) |
color | Orange to Very Dark Purple |
Merck | 14,2589 |
Stability | Light Sensitive |
InChIKey | OXNHRKGZZFWUQZ-QORFUXSJSA-N |
LogP | -4.742 (est) |
CAS DataBase Reference | 42553-65-1 |
EWG's Food Scores | 1 |
FDA UNII | 877GWI46C2 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
Safety Statements | 24/25 |
WGK Germany | 3 |
RTECS | HL7380000 |
F | 1-8-10 |
HS Code | 32129000 |
Crocin price More Price(46)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 17304 | Crocin for microscopy | 42553-65-1 | 1g | $58.4 | 2024-03-01 | Buy |
Sigma-Aldrich | PHL80391 | Crocin phyproof? Reference Substance | 10MG | $187 | 2024-03-01 | Buy | |
Sigma-Aldrich | 17304 | Crocin for microscopy | 42553-65-1 | 5g | $186 | 2024-03-01 | Buy |
TCI Chemical | C1527 | Crocin (Gardenia Fruits Extract) | 42553-65-1 | 25g | $184 | 2024-03-01 | Buy |
Cayman Chemical | 26337 | Crocin/Gardenia Extract | 42553-65-1 | 500mg | $32 | 2024-03-01 | Buy |
Crocin Chemical Properties,Uses,Production
Introduction
Crocin (crocin) is also known as a-crocin and crocetin. It is a series of ester glycosides combining water-soluble carotenoids crocetin and different sugars. It is one of the main active ingredients of saffron, including crocin -1, crocin -2, crocin -3, crocin-4 and crocetin.It is centrally acting antihypertensive and can prevent atherosclerosis and be of antithrombosis, antiplatelet aggregation, and anti myocardial ischemia.
Efficacy and effect
The traditional medicine believes that the stigma croci can dredge and activate the collaterals, remove blood stasis, eradicate depression and relieve swelling and pain. It is mainly used for the treatment of anxiety depression, chest distention, irregular menstruation, postpartum haemorrhage and traumatic injury. The main effective components are crocetin and crocin, which has many pharmacological activities, such as being anti-inflammatory and analgesic, antitumor, antidepressant, hypoglycemic and lowering blood pressure. Because the water solution of stigma croci is bright yellow with sweet smell, it is often used as a food additive and high-grade edible pigment, but also can be used as high dye for silk, cotton and wool products. In recent years, pharmacological researches indicate that stigma croci has good control effect for a variety of diseases, including cancer, coronary heart disease, atherosclerosis and hyperlipidemia.
Pharmacological effects
Crocin has the effect of the anti-inflammation and treatment of soft tissue injury, gall liver protection, anti-tumor and other pharmacological effects. It is widely used in food, medicine, chemical industry and other industries. It is used in the treatment of patients with cardiovascular disease and fatty liver.with good medicinal value.
Description
Crocin/Gardenia Extract is a Gardenia extract that contains crocin I, II, and III, and crocetin, among other compounds.
Chemical Properties
Crocin is a reddish brown needle-like crystal. Slightly odor. Easily soluble in hot water, becomes the orange solution. Slightly soluble in anhydrous ethanol, ether, and other organic solvents. Insoluble in oil. The aqueous solution is weakly acidic or neutral transparent bright yellow, with a maximum absorption wavelength of 442nm. color is almost unaffected by pH value. Light and heat resistance is good in neutral or alkaline, and poor in acidic. Metal ion resistance (except iron, blackened by iron) is good. The coloring of protein is better than that of starch and is not affected by pH (pH4-10).
Uses
Crocin, is a natural carotenoid derived the flowers crocus and gardenia. Crocin has been shown to be a potent antioxidant. It has also been shown to have an antiproliferative action against cancer cells in vitro, and also possessing possible antidepressant properties.
Definition
ChEBI: Crocin-1 is a diester that is crocetin in which both of the carboxy groups have been converted to their gentiobiosyl esters. It is one of the water-soluble yellow-red pigments of saffron and is used as a spice for flavouring and colouring food. Note that in India, the term 'Crocin' is also used by GlaxoSmithKline as a brand-name for paracetamol. It has a role as an antioxidant, a food colouring, a plant metabolite and a histological dye. It is a diester, a disaccharide derivative and a diterpenoid. It is functionally related to a beta-D-gentiobiosyl crocetin and a gentiobiose.
General Description
Crocin (CR) is a water-soluble carotenoid found in Gardenia jasmi-noides Ellis and Crocus sativus (saffron). It has two D-gentiobioside glycosyl esters in its structure. CR is one of the major bioactive compounds of saffron contributing to its red color. A highly unsaturared diterpene dicarboxylic acid ester found in saffron.
Biochem/physiol Actions
Crocin alleviates some ethanol-induced impairments of learning and prevents ethanol-induced inhibition of hippocampal long-term potentiation (LTP), a form of activity-dependent synaptic plasticity that may underly learning and memory. Related CNS effects are specific to the digentiobiose ester; crocetin glucose gentiobiose ester is half as potent, and the diglucose ester has no effect at all.
Crocin Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3772 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12502 | 58 |
Henan Bao Enluo International TradeCo.,LTD | +86-17331933971 +86-17331933971 | deasea125996@gmail.com | China | 2503 | 58 |
BINBO BIOLOGICAL CO.,LTD | +8618629063126 | info@binbobiological.com | China | 346 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21663 | 55 |
Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
Chengdu Greenpure Biopharma CO.,Ltd | 18283602253; +8618283602253 | jancyzheng@gcgreenpure.com | China | 953 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29890 | 58 |
Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
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View Lastest Price from Crocin manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-10-09 | Crocin; Saffron Extract; Gardenia Extract
42553-65-1
|
US $0.00 / KG | 1KG | 40%-99% HPLC | 1000KG | Changsha Staherb Natural Ingredients Co., Ltd. | ||
2024-09-28 | CROCIN
42553-65-1
|
US $3660.00-3600.00 / kg | 1kg | 99.99% | 100Tons | Hebei Dangtong Import and export Co LTD | ||
2024-04-27 | Crocin
42553-65-1
|
US $0.00 / kg | 1kg | 40% 50% 55% 95% | 1000 kg | BINBO BIOLOGICAL CO.,LTD |
- Crocin; Saffron Extract; Gardenia Extract
42553-65-1
- US $0.00 / KG
- 40%-99% HPLC
- Changsha Staherb Natural Ingredients Co., Ltd.
- CROCIN
42553-65-1
- US $3660.00-3600.00 / kg
- 99.99%
- Hebei Dangtong Import and export Co LTD
- Crocin
42553-65-1
- US $0.00 / kg
- 40% 50% 55% 95%
- BINBO BIOLOGICAL CO.,LTD