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ChemicalBook >> CAS DataBase List >>(2S-cis)-(+)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one

(2S-cis)-(+)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one

(2S-cis)-(+)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one Structure
(2S-cis)-(+)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one structure
CAS No.
42399-49-5
Chemical Name:
(2S-cis)-(+)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one
Synonyms
HYDROXY LACTAM;(2S,3S)-DHMB;96.0%(LC&DiltiazeM IMpurity E;(2S) -cis-hydroxy lactam;CIS(+) HYDROXY DILTIAZEM;(2S,3S)-3-Hydroxy-2-(4-methoxypheny;Diltiazem Hydrochloride EP Impurity E;Des[3-Acetyl-5-(2-dimethylamino)ethyl] Diltiazem;3-hydroxy-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one
CBNumber:
CB2319542
Molecular Formula:
C16H15NO3S
Molecular Weight:
301.36
MDL Number:
MFCD01321316
MOL File:
42399-49-5.mol
Last updated:2024-11-13 18:13:23
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(2S-cis)-(+)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one Properties

Melting point 203-206 °C(lit.)
alpha 112 º (c=0.5 in MeOH)
Boiling point 545.4±50.0 °C(Predicted)
Density 1.2458 (rough estimate)
refractive index 114 ° (C=0.5, MeOH)
storage temp. Sealed in dry,2-8°C
solubility DMSO (Slightly), Methanol (Slightly, Sonicated)
pka 12.37±0.40(Predicted)
form Solid
color Off-White
InChIKey LHBHZALHFIQJGJ-CABCVRRESA-N
CAS DataBase Reference 42399-49-5(CAS DataBase Reference)
FDA UNII 6RN4N3305M

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
HS Code  29349990
NFPA 704
0
2 0

(2S-cis)-(+)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one price More Price(20)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical D3661 (2S,3S)-(+)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one >96.0%(HPLC)(N) 42399-49-5 5g $36 2024-03-01 Buy
TCI Chemical D3661 (2S,3S)-(+)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one >96.0%(HPLC)(N) 42399-49-5 25g $111 2024-03-01 Buy
TRC D288450 Des[3-Acetyl-5-(2-dimethylamino)ethyl]Diltiazem 42399-49-5 50mg $80 2021-12-16 Buy
Biosynth Carbosynth FD21106 Des[3-acetyl-5-(2-dimethylamino)ethyl] diltiazem 42399-49-5 50g $95 2021-12-16 Buy
Biosynth Carbosynth FD21106 Des[3-acetyl-5-(2-dimethylamino)ethyl] diltiazem 42399-49-5 25g $55 2021-12-16 Buy
Product number Packaging Price Buy
D3661 5g $36 Buy
D3661 25g $111 Buy
D288450 50mg $80 Buy
FD21106 50g $95 Buy
FD21106 25g $55 Buy

(2S-cis)-(+)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one Chemical Properties,Uses,Production

Chemical Properties

white to slightly beige powder

Uses

A key intermediate for Diltiazem (D460620) synthesis.

(2S-cis)-(+)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one Preparation Products And Raw materials

Raw materials

Preparation Products

Diltiazem

(2S-cis)-(+)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one Suppliers

Global( 203)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Daken Advanced Materials Co.,Ltd 		+86-371-66670886 info@dakenam.com China 18751 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21634 55
Hubei Jusheng Technology Co.,Ltd. 		18871490254 linda@hubeijusheng.com CHINA 28172 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49374 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29811 58
SIMAGCHEM CORP 		+86-13806087780 sale@simagchem.com China 17365 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58
Dideu Industries Group Limited 		+86-29-89586680 +86-15129568250 1026@dideu.com China 22784 58
AFINE CHEMICALS LIMITED 		+86-0571-85134551 sales@afinechem.com China 15352 58
Dayang Chem (Hangzhou) Co.,Ltd. 		571-88938639 +8617705817739 info@dycnchem.com China 52849 58
Supplier Advantage
Shanghai Daken Advanced Materials Co.,Ltd 		58
Henan Tianfu Chemical Co.,Ltd. 		55
Hubei Jusheng Technology Co.,Ltd. 		58
CONIER CHEM AND PHARMA LIMITED 		58
career henan chemical co 		58
SIMAGCHEM CORP 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58
Dideu Industries Group Limited 		58
AFINE CHEMICALS LIMITED 		58
Dayang Chem (Hangzhou) Co.,Ltd. 		58

View Lastest Price from (2S-cis)-(+)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(2S-cis)-(+)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one pictures 2024-11-18 (2S-cis)-(+)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one
42399-49-5
 US $0.00 / KG 1KG 98.0% 10000KGS Shaanxi Dideu New Materials Co. Ltd
Hydroxy Lactam pictures 2024-11-18 Hydroxy Lactam
42399-49-5
 US $0.00 / KG 1KG 99% 100000KGS Shaanxi Dideu New Materials Co. Ltd
(2S-cis)-(+)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one USP/EP/BP pictures 2021-07-29 (2S-cis)-(+)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one USP/EP/BP
42399-49-5
 US $1.10 / g 1g 99.9% 100 Tons min Dideu Industries Group Limited
  • Hydroxy Lactam pictures
  • Hydroxy Lactam
    42399-49-5
  • US $0.00 / KG
  • 99%
  • Shaanxi Dideu New Materials Co. Ltd

42399-49-5((2S-cis)-(+)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one)Related Search:

CHLOROPHOSPHONAZO III Diltiazem Impurity 3 (2S,3S)-3-(Acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one 1-oxide N-DESMETHYLDILTIAZEM, HYDROCHLORIDE DESACETYL DILTIAZEM HCL
Diltiazem EP Impurity B Diltiazem EP Impurity C Glycolic acid Hydroxy silicone oil 2-Phenylphenol
Triphenylphosphine Hydroxyapatite 4-Amino-5-chloro-N-(2-(diethylamino)ethyl)-2-methoxybenzamide Methoxyammonium chloride Camptothecin Series--10-hydroxycamptothecin
Phenylacetone (+)-5-[2-(Dimethylamino)ethyl]-cis-2,3-dihydro-3-hydroxy-2-(p-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one acetate (ester) (2S-cis)-(+)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one

1of4

(2S-CIS)-(+)-2,3-DIHYDRO-3-HYDROXY-2-(4-METHOXYPHENYL)-1,5-BENZOTHIAZEPIN-4(5H)-ONE (2S-cis)-(+)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one ,99% DiltiazeM IMpurity E 3-hydroxy-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one (2S,3S)-3-Hydroxy-2-(4-methoxyphenyl)-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one (2S,3S)-(+)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one Des[3-Acetyl-5-(2-dimethylamino)ethyl] Diltiazem 5-benzothiazepin-4(5h)-one,2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-(2s-c CIS-2,3-DIHYDRO-3-HYDROXY-2-(4-METHOXYPHENYL)-1,5-BENZOTHIAZEPIN-4(5H)-ONE (2S-CIS)-(+)-DIHYDRO-3-OH-2-(4-MEO-PH)-1 ,5-BENZOTHIAZEPIN-4(5H)-ONE, 98% (2S,3S)-(+)-3-Hydroxy-2-(4'-Methoxyphenyl)-2.3-Dihydro-1,5-Benzothiazepin-4(5H)-One[Cis-(+)-HydroxyLactam] 1,5-Benzothiazepin-4(5H)-one, 2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-, (2S-cis) (2S-CIS)-2,3-DIHYDRO-3-HYDROXY-2-(4-METHOXYPHENYL)-1,5-BENZOTHIAZEPIN- (2S)-cis-(+)-2， 3-Dihydro-3-hydroxy-2- (4-methoxyphenyl)-1，5-benzothiazepin- 4(5H)-one (cis-Lactam) (2S,3S)-(+)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one (2S)-2,3-Dihydro-3β-hydroxy-2β-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one (2S)-2β-(4-Methoxyphenyl)-3β-hydroxy-2,3,4,5-tetrahydro-1,5-benzothiazepine-4-one (2S,3S)-DHMB (2S-cis)-(+)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one,98% (2S-cis)-(+)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one(Dilthiazem hydrochloride) 3-hydroxy-2-(4-methoxyphenyl)-3,5-dihydro-2H-1,5-benzothiazepin-4-one (2S,3S)-(+)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one> (2S,3S)-3-Hydroxy-2-(4-methoxypheny 96.0%(LC& 1,5-Benzothiazepin-4(5H)-one, 2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-, (2S,3S)- (2S,3S)-3-hydroxy-2-(4-methoxyphenyl)-2,3,4,5-tet rahydro-1,5-benzothiazepin-4-one (2S,3S)-3-HYDROXY-2-(4-METHOXYPHENYL)-2,3-DIHYDRO-1,5-BENZOTHIAZEPIN- (2S-cis)-(+)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one USP/EP/BP (2S-cis)-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzo... (2S-cis)-(+)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-b 42399-49-5 HYDROXY LACTAM (2S) -cis-hydroxy lactam CIS(+) HYDROXY DILTIAZEM (2S,3S)-(+)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one, ≥ 96.0% Diltiazem EP Impurity E (2S,3S)-3-Hydroxy-2-(4-methoxyphenyl)-2,3- dihydro-1,5-benzothiazepin-4(5H)-one Diltiazem Hydrochloride EP Impurity E 42399-49-5 C16H15NO3S Heterocyclic Building Blocks Others Chiral Building Blocks Asymmetric Synthesis Pharmaceutical Intermediates Chiral Building Blocks Heterocyclic Building Blocks Others Heterocycles series INTERMEDIATESOFDILTIAZEM API intermediates Aromatics Chiral Reagents Intermediates & Fine Chemicals Pharmaceuticals Sulfur & Selenium Compounds