ChemicalBook >> CAS DataBase List >>GS 39783
GS 39783
- CAS No.
- 39069-52-8
- Chemical Name:
- GS 39783
- Synonyms
- GS 39783;N,N'-DICYCLOPENTYL-2-(METHYLTHIO)-5-NITRO-4,6-PYRIMIDINEDIAMINE;N4,N6-Dicyclopentyl-2-(methylthio)-5-nitropyrimidine-4,6-diamine;N,N'-Dicyclopentyl-2-(methylthio)-5-nitro-4,6-pyrimidinediaamine;4,6-Pyrimidinediamine, N4,N6-dicyclopentyl-2-(methylthio)-5-nitro-;N,N'-DICYCLOPENTYL-2-METHYLSULFANYL-5-NITRO-PYRIMIDINE-4,6-DIAMINE
- CBNumber:
- CB2323806
- Molecular Formula:
- C15H23N5O2S
- Molecular Weight:
- 337.44
- MDL Number:
- MFCD06201849
- MOL File:
- 39069-52-8.mol
Last updated:2023-06-30 15:45:59
| storage temp. | Store at RT |
|---|---|
| solubility | DMSO: ~8 mg/mL |
| form | powder |
| color | yellow |
| FDA UNII | HD3T22A5DM |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P301+P312+P330-P305+P351+P338 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| NFPA 704 |
|
GS 39783 price More Price(19)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML1520 | GS39783 ≥98% (HPLC) | 39069-52-8 | 5mg | $95.7 | 2022-05-15 | Buy |
| Sigma-Aldrich | SML1520 | GS39783 ≥98% (HPLC) | 39069-52-8 | 25mg | $386 | 2022-05-15 | Buy |
| Cayman Chemical | 29482 | GS-39783 | 39069-52-8 | 5mg | $68 | 2024-03-01 | Buy |
| Cayman Chemical | 29482 | GS-39783 | 39069-52-8 | 10mg | $121 | 2024-03-01 | Buy |
| Cayman Chemical | 29482 | GS-39783 | 39069-52-8 | 25mg | $286 | 2024-03-01 | Buy |
GS 39783 Chemical Properties,Uses,Production
Uses
GS 39783 is an allosteric positive modulator of GABAB receptors. GS 39783 attenuates acute cocaine-induced hyperlocomotion and blocks cocaine-induced Fos induction in the striatal complex.
Definition
ChEBI: N4,N6-dicyclopentyl-2-(methylthio)-5-nitropyrimidine-4,6-diamine is an aryl sulfide.
Biological Activity
Novel positive allosteric modulator of GABA B receptor function. Potentiates the effects of GABA on [ 35 S]GTP γ S binding at recombinant and native GABA B receptors (EC 50 values are 2.1 and 3.1 μ M respectively). Decreases cocaine self-administration, blocks the rewarding properties of nicotine and produces anxiolytic-like activity without the side effects associated with baclofen or benzodiazepines.
storage
Store at RT
GS 39783 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 42)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| Shanghai T&W Pharmaceutical Co., Ltd. | +86 21 61551611 | China | 9900 | 58 | |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8449 | 60 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9707 | 58 |
| Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 3770 | 55 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 | sales@rrkchem.com | China | 56077 | 58 |
| Jiangsu aikang biomedical research and development co., LTD | 025-66110311 13155353615 | qzhang@aikonchem.com | China | 15527 | 58 |
39069-52-8(GS 39783)Related Search:
N,N'-DICYCLOPENTYL-2-METHYLSULFANYL-5-NITRO-PYRIMIDINE-4,6-DIAMINE
N,N'-DICYCLOPENTYL-2-(METHYLTHIO)-5-NITRO-4,6-PYRIMIDINEDIAMINE
GS 39783
N,N'-Dicyclopentyl-2-(methylthio)-5-nitro-4,6-pyrimidinediaamine
N4,N6-Dicyclopentyl-2-(methylthio)-5-nitropyrimidine-4,6-diamine
4,6-Pyrimidinediamine, N4,N6-dicyclopentyl-2-(methylthio)-5-nitro-
39069-52-8
GABA/Glycine receptor