SINIGRIN
- CAS No.
- 3952-98-5
- Chemical Name:
- SINIGRIN
- Synonyms
- GLUCOSINOLATE;Sinigrine;SINIGRIN;Ccris 3715;SINOGROSIDE;Mustard seed;sinigrin(1-);(-)-Sinigrin;SINIGRIN hplc;beta-d-siumsal
- CBNumber:
- CB2333728
- Molecular Formula:
- C10H17NO9S2.K
- Molecular Weight:
- 397.46
- MDL Number:
- MFCD00006616
- MOL File:
- 3952-98-5.mol
- MSDS File:
- SDS
| Melting point | 128 (dec.)(lit.) |
|---|---|
| storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| solubility | DMSO (Slightly), Methanol (Slightly), Water (Slightly) |
| form | Solid |
| color | White |
| biological source | plant (Brassica nigra) |
| optical activity | [α]20/D 17±1°, c = 1% in H2O |
| Water Solubility | almost transparency |
| Merck | 14,8545 |
| Stability | Hygroscopic |
| LogP | 1.049 (est) |
| CAS DataBase Reference | 3952-98-5 |
| FDA UNII | 50UM64RMBJ |
| UNSPSC Code | 85151701 |
| NACRES | NA.25 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P280-P305+P351+P338-P310 |
| Safety Statements | 24/25 |
| WGK Germany | 3 |
| RTECS | LZ5778000 |
| HS Code | 29389090 |
SINIGRIN price More Price(31)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 85440 | (?)-Sinigrin hydrate ≥99.0% (TLC) | 3952-98-5 | 1g | $617 | 2024-03-01 | Buy |
| Sigma-Aldrich | 00290 | (?)-Sinigrin hydrate analytical standard | 3952-98-5 | 10mg | $180 | 2024-03-01 | Buy |
| TCI Chemical | S0156 | Sinigrin Hydrate >98.0%(HPLC) | 3952-98-5 | 100mg | $246 | 2024-03-01 | Buy |
| Sigma-Aldrich | S1647 | (?)-Sinigrin hydrate from horseradish | 3952-98-5 | 500mg | $709 | 2024-03-01 | Buy |
| Sigma-Aldrich | S1647 | (?)-Sinigrin hydrate from horseradish | 3952-98-5 | 1g | $798 | 2024-03-01 | Buy |
SINIGRIN Chemical Properties,Uses,Production
Uses
Sinigrine, is a glucosinolate which is found naturally in Cruciferae including the genus Brassica. When enzymatically hydrolysed, Sinigrine yields isothiocyanates and give a pungent taste. Both Sinigrine, and isothiocyanates, have been shown to have anticancer activity as well as antifungal and antibacterial properties.
Uses
Sinigrin, a glucosinolate, is used as a systrate to identify, differentiate and characterize myrosinase(s)/thioglucoside glucohydrolase(s)/thioglucosidase(s). Sinigrin is used as a reference material in procedures for the isolation and identification of glucosinolates.
Definition
ChEBI: An alkenylglucosinolate that is the conjugate base of sinigrin.
Biochem/physiol Actions
A β-D-thioglucopyranoside occurring in black mustard seeds and horseradish root. Substrate for thioglucosidase.
in vivo
Sinigrin (15-30 mg/kg; Oral administration; for 12 days) exerts protective and therapeutic effects on DSS?induced colitis, by enhancing the anti-oxidant enzymes and suppressing the intestinal inflammatory cascade of markers by regulating the MAPK pathway[2].
| Animal Model: | A dextran sulfate sodium (DSS)-induced mouse model[2] |
| Dosage: | 15 mg/kg or 30 mg/kg |
| Administration: | Oral administration; for 12 days |
| Result: | Significantly mitigated the DSS-induced body weight loss, attenuated the colon length shrinkage, and improved the disease index score. Successfully abrogated the DSS-induced IL-17 levels and improved the colonic barrier in colon tissues. |
SINIGRIN Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21628 | 55 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29859 | 58 |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +8618080483897 | sales@biopurify.com | China | 3772 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49732 | 58 |
View Lastest Price from SINIGRIN manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-19 | Sinigrin
3952-98-5
|
US $69.00-0.00 / mg | 98.92% | 10g | TargetMol Chemicals Inc. | ||
 |
2023-02-24 | Sinigrin
3952-98-5
|
US $0.00 / mg | 20mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. | |
 |
2019-07-06 | SINIGRIN
3952-98-5
|
US $1.00 / kg | 1kg | 95%-99% | 10kg | Career Henan Chemical Co |