Tos-PEG5-CH2CO2H
- CAS No.
- 2028284-73-1
- Chemical Name:
- Tos-PEG5-CH2CO2H
- Synonyms
- Tos-PEG5-CH2CO2H;Tos-PEG4-CH2COOH;Tos-PEG5-CH2COOH;14-(Tosyloxy)-3,6,9,12-tetraoxatetradecanoic acid;14-[(4-methylbenzenesulfonyl)oxy]-3,6,9,12-tetraoxatetradecanoic acid;Acetic acid, 2-[2-[2-[2-[2-[[(4-methylphenyl)sulfonyl]oxy]ethoxy]ethoxy]ethoxy]ethoxy]-
- CBNumber:
- CB23364037
- Molecular Formula:
- C17H26O9S
- Molecular Weight:
- 406.45
- MDL Number:
- MFCD30458013
- MOL File:
- 2028284-73-1.mol
Tos-PEG5-CH2CO2H price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| BroadPharm | BP-23360 | Tos-PEG5-CH2CO2H 96% | 2028284-73-1 | 250mg | $350 | 2021-12-16 | Buy |
| BroadPharm | BP-23360 | Tos-PEG5-CH2CO2H 96% | 2028284-73-1 | 500mg | $560 | 2021-12-16 | Buy |
| BroadPharm | BP-23360 | Tos-PEG5-CH2CO2H 96% | 2028284-73-1 | 1g | $880 | 2021-12-16 | Buy |
Tos-PEG5-CH2CO2H Chemical Properties,Uses,Production
Description
Tos-PEG5-CH2CO2H is a PEG linker containing a tosyl group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Uses
Tos-PEG4-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34. DOI:10.1038/s12276-018-0065-6
Tos-PEG5-CH2CO2H Preparation Products And Raw materials
Raw materials
Preparation Products
Tos-PEG5-CH2CO2H Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32159 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
| Jinan elephant international trading co., LTD | 13006575422@163.com | China | 6355 | 58 | |
| Shanghai Chaolan Chemical Technology Center | 021-QQ：65489617 15618227136 | Sales@ATKchemical.com | China | 9330 | 58 |
| Shaanxi Xinyan Bomei Biotechnology Co., Ltd. | 029-86217788 13892832556 | 2440688701@qq.com | China | 1986 | 58 |
| Zhengzhou Convergence Chemical Co. LTD | 0371-0371-53736046 13393710386 | 2853979814@qq.com | China | 9992 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 025-85563444 18351873721 | purchase@synzest.com | China | 10434 | 58 |
| Zhengzhou Akem Chemical Co., Ltd | 13303867194 | 3001317055@qq.com | China | 9967 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223; | psaitong@jm-bio.com | China | 29774 | 58 |
| Bide Pharmatech Ltd. | 400-1647117 13681763483 | product02@bidepharm.com | China | 62072 | 58 |