ChemicalBook >> CAS DataBase List >>Aminoacetaldehyde dimethyl acetal
Aminoacetaldehyde dimethyl acetal
- CAS No.
- 22483-09-6
- Chemical Name:
- Aminoacetaldehyde dimethyl acetal
- Synonyms
- AMINOACETALDEHYDE DIMETHYL ACETAL;2,2-Dimethoxyethanamine;AMINOACETOLDEHYDE DIMETHYL ACETOL;2,2-Dimethyethanamine;Aminoacetaldehyde dimethyl acetal ,98%;AMINOACETALDEHYDE DIMETHYL ACETAL (OR) 2,2- DIMETHOXYETHYLAMINE (ADMA);anjiahuanchun;DIMETHYLAMINOACETAL;Dimethoxyethylamine;Aminoacetaldehyde di
- CBNumber:
- CB2394455
- Molecular Formula:
- C4H11NO2
- Molecular Weight:
- 105.14
- MDL Number:
- MFCD00008135
- MOL File:
- 22483-09-6.mol
- MSDS File:
- SDS
Last updated:2024-10-31 13:32:20
| Melting point | -78°C |
|---|---|
| Boiling point | 135-139 °C/95 mmHg (lit.) |
| Density | 0.965 g/mL at 25 °C (lit.) |
| refractive index |
n |
| Flash point | 128 °F |
| storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
| solubility | soluble in Chloroform, Methanol |
| pka | 6.95±0.10(Predicted) |
| form | Liquid |
| color | Clear colorless to pale yellow |
| Water Solubility | miscible |
| BRN | 741868 |
| InChIKey | QKWWDTYDYOFRJL-UHFFFAOYSA-N |
| CAS DataBase Reference | 22483-09-6(CAS DataBase Reference) |
| FDA UNII | XF4JYB7VV5 |
| NIST Chemistry Reference | Aminoacetaldehyde dimethyl acetal(22483-09-6) |
| EPA Substance Registry System | Ethanamine, 2,2-dimethoxy- (22483-09-6) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H226-H314 | |||||||||
| Precautionary statements | P210-P233-P240-P280-P303+P361+P353-P305+P351+P338 | |||||||||
| Hazard Codes | C,F,Xi | |||||||||
| Risk Statements | 10-34-36/37/38 | |||||||||
| Safety Statements | 26-36/37/39-45-16-36 | |||||||||
| RIDADR | UN 1993 3/PG 3 | |||||||||
| WGK Germany | 2 | |||||||||
| Hazard Note | Flammable/Corrosive | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 3 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29225000 | |||||||||
| NFPA 704 |
|
Aminoacetaldehyde dimethyl acetal price More Price(44)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 121967 | Aminoacetaldehyde dimethyl acetal 99% | 22483-09-6 | 25ml | $64.5 | 2024-03-01 | Buy |
| Sigma-Aldrich | 121967 | Aminoacetaldehyde dimethyl acetal 99% | 22483-09-6 | 100ml | $171 | 2024-03-01 | Buy |
| TCI Chemical | A0801 | Aminoacetaldehyde Dimethyl Acetal >98.0%(GC)(T) | 22483-09-6 | 25mL | $38 | 2024-03-01 | Buy |
| TCI Chemical | A0801 | Aminoacetaldehyde Dimethyl Acetal >98.0%(GC)(T) | 22483-09-6 | 250mL | $289 | 2024-03-01 | Buy |
| Alfa Aesar | A15498 | Aminoacetaldehyde dimethyl acetal, 99% | 22483-09-6 | 25g | $47.65 | 2024-03-01 | Buy |
Aminoacetaldehyde dimethyl acetal Chemical Properties,Uses,Production
Description
Aminoacetaldehyde dimethyl acetal, also known as 2,2-dimethoxy-ethylamine, is a critical intermediate in the synthesis of ivabradine hydrochloride, proline analogs, praziquantel, and other raw materials. The existing process for producing aminoacetal dimethyl acetate uses vinyl acetate as the starting material, and the target product is synthesized through bromination, Gabriel synthesis, and hydrazinolysis.
Chemical Properties
clear colorless to pale yellow liquid
Uses
Amino acetaldehyde dimethyl was used in preparation of chitosan- dendrimer hybrids having various functional groups such as carboxyl, ester and poly(ethylene glycol). It was used in an synthesis of a bicyclic proline analog from L-ascorbic acid and in 3-component reaction catalyzed by MgClO4 leading to α-aminophosphonates.
General Description
Aminoacetaldehyde dimethyl acetal reacts with sulfone, followed by hydrolysis and reductive amination by adding desired piperazine derivative to yield piperazine derivatives of 2-furanyl[1,2,4]triazolo[1,5-a][1,3,5]triazine.
Purification Methods
Dry the acetal over KOH pellets and distil it through a 30cm vacuum jacketed Vigreux column (p 11). [Lawson J Am Chem Soc 75 3398 1953, Erickson et al. J Am Chem Soc 77 6640 1955, Beilstein 4 IV 1918.]
Aminoacetaldehyde dimethyl acetal Preparation Products And Raw materials
Raw materials
Preparation Products
ethyl 2-(3-bromo-2-oxopyrazin-1(2H)-yl)acetate
6-Bromoisoquinoline
ethyl 2-(3,4-dihydro-2,3-dioxopyrazin-1(2H)-yl)acetate
6-(bromomethyl)isoquinoline
6-Methylisoquinoline
2-MERCAPTOIMIDAZOLE
8-METHYL-ISOQUINOLINE
2-Aminoimidazole
1-Methyl-1,3-dihydro-imidazol-2-one
Glycine, N-(2,2-dimethoxyethyl)-, ethyl ester
1of4
Global( 575)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Asia Chem I and E (Jiangsu) Co Ltd | +8615105181882 | mera.z@nitrobenzenechemical.com | China | 132 | 58 |
| Hangzhou Qiwei Pharmatech Co.,Ltd | 13282840061 | mw@qwpharmatech.com | China | 109 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12839 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 5857 | 58 |
| Hebei Weibang Biotechnology Co., Ltd | +8617732866630 | bess@weibangbio.com | China | 18153 | 58 |
| Hangzhou ICH Biofarm Co., Ltd | +86-0571-28186870; +undefined8613073685410 | sales@ichemie.com | China | 998 | 58 |
| airuikechemical co., ltd. | +undefined86-15315557071 | sales02@sdzhonghuimaterial.com | China | 983 | 58 |
| hebei hongtan Biotechnology Co., Ltd | +86-86-1913198-3935 +8617331935328 | sales03@chemcn.cn | China | 970 | 58 |
| Apeloa production Co.,Limited | +8619933239880 | admin@apcl.com.cn | China | 852 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 3002 | 58 |
Related articles
- Aminoacetaldehyde Dimethyl Acetal: Crucial Role in Medicinal Chemistry and its Production Method
- Aminoacetaldehyde dimethyl acetal (also known as 2,2-dimethoxy-ethylamine) is the key intermediate of bulk drugs such as proli....
- Oct 24，2024
View Lastest Price from Aminoacetaldehyde dimethyl acetal manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-25 | Aminoacetaldehyde dimethyl acetal
22483-09-6
|
US $70.00-25.00 / kg | 1kg | 99% | 20ton | Hebei Zhuanglai Chemical Trading Co.,Ltd | |
 |
2024-11-25 | Aminoacetaldehyde dimethyl acetal
22483-09-6
|
US $39.10 / Kg/Drum | 200Kg/Drum | 99.00%HPLC | 10tons/month | Asia Chem I and E (Jiangsu) Co Ltd | |
 |
2024-11-25 | 2,2-Dimethoxyethylamine
22483-09-6
|
US $0.00 / KG | 1KG | ≥99% | 1000mt/year | Jinan Finer Chemical Co., Ltd |
-
- Aminoacetaldehyde dimethyl acetal
22483-09-6
- US $70.00-25.00 / kg
- 99%
- Hebei Zhuanglai Chemical Trading Co.,Ltd
-
- Aminoacetaldehyde dimethyl acetal
22483-09-6
- US $39.10 / Kg/Drum
- 99.00%HPLC
- Asia Chem I and E (Jiangsu) Co Ltd
-
- 2,2-Dimethoxyethylamine
22483-09-6
- US $0.00 / KG
- ≥99%
- Jinan Finer Chemical Co., Ltd
22483-09-6(Aminoacetaldehyde dimethyl acetal)Related Search:
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AMINOACETOLDEHYDE DIMETHYL ACETOL
Aminoacetaldehyde dimethyl acetal ,98%
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2,2-Dimethoxyethanamine
AMINOACETALDEHYDE DIMETHYL ACETAL
AMINOACETALDEHYDE DIMETHYL ACETAL (OR) 2,2- DIMETHOXYETHYLAMINE (ADMA)
2,2-DIMETHOXY ETHYLAMINE(ADMA)
2'2-Dimethoxyethylamine
22483-09-6
22483-09-06
22483-09-5
22483-09-4
22843-09-6
H2NCH2CHOCH32
CH32NCH2CHOC2H52
NH2CH2CHOCH32
Aldehydes
Acetals/Ketals/Ortho Esters
Organic Building Blocks
Oxygen Compounds
Carbonyl Compounds
C1 to C6
Building Blocks
Pharmaceutical Intermediates
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22483-09-6