Elastase
storage temp. | -20°C |
---|---|
form | lyophilized powder |
color | White to off-white |
CAS DataBase Reference | 9004-06-2 |
EWG's Food Scores | 1 |
FDA UNII | U2974059LF |
EPA Substance Registry System | Elastase (9004-06-2) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07,GHS08 |
---|---|
Signal word | Danger |
Hazard statements | H315-H319-H334-H335 |
Precautionary statements | P261-P264-P271-P302+P352-P304+P340+P312-P305+P351+P338 |
Hazard Codes | B |
WGK Germany | 3 |
F | 3-10 |
Elastase price More Price(9)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | SAB1305716 | ANTI-NEUTROPHIL ELASTASE(N-TERMINAL) antibody produced in rabbit affinity isolated antibody, buffered aqueous solution | 9004-06-2 | 400μl | $481 | 2024-03-01 | Buy |
Sigma-Aldrich | E8140 | Elastase from human leukocytes lyophilized powder, ≥50?units/mg protein (Bradford) | 9004-06-2 | 1unit | $228 | 2024-03-01 | Buy |
Sigma-Aldrich | 324681 | Elastase, Human Neutrophil Elastase, Human Neutrophil, CAS 9004-06-2, is a serine protease that degrades elastin, collagen, and proteoglycans | 9004-06-2 | 50μg | $318 | 2024-03-01 | Buy |
Sigma-Aldrich | 324681 | Elastase, Human Neutrophil Elastase, Human Neutrophil, CAS 9004-06-2, is a serine protease that degrades elastin, collagen, and proteoglycans | 9004-06-2 | 100μg | $513 | 2024-03-01 | Buy |
Usbiological | E2255-25 | Elastase, Human Neutrophil | 9004-06-2 | 100ug | $583 | 2021-12-16 | Buy |
Elastase Chemical Properties,Uses,Production
Uses
Elastase from human leukocytes has been used:
- to measure serum elastase activity
- in proteolytic digestion of fibronectin and salivary glands
- in neutrophil elastase (NE) activity assay
- cell-free NE digestion of E-cadherin
- scratch wound assay
- in a study that determined that fragments of Nle3-angiotensin(1-7) accelerate healing in dermal models
General Description
Elastase is a proteolytic enzyme. It is a member of the subgroup named, peptidyl peptide hydrolases. It is a major anatomic constituent of arteries. It is mainly found in the pancreas and pancreatic juice of various birds and mammals. It is also present in human serum, granulocytes and erythrocytes.
Biochem/physiol Actions
Elastase enzyme is capable of releasing soluble peptides from insoluble elastin fibers with the help of a proteolytic process. It can stimulate disintegration of the axoneme with the help of adenosine triphosphate (ATP). Unlike pancreatic elastase the leukocyte enzyme has a preferential cleavage for the carboxyl side of valine, but will also cleave to a lesser extent after alanine. Natural substrates include elastin, cartilage proteoglycans, collagen types I, II, II and IV, and fibronectin.
Elastase Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 22784 | 58 |
AFINE CHEMICALS LIMITED | +86-0571-85134551 | sales@afinechem.com | China | 15352 | 58 |
SUZHOU SENFEIDA CHEMICAL CO.,LTD | +86-0512-83500002 +8615195660023 | sales@senfeida.com | China | 23046 | 58 |
Greek Shandong Pharmaceutical Co., Ltd. | 010-63830020 | China | 3 | 60 | |
J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15839 | 69 |
Hangzhou Yuhao Chemical Technology Co., Ltd | 0571-82693216 | info@yuhaochemical.com | China | 9387 | 52 |
Wuhan Fortuna Chemical Co., Ltd | 027-59207852 13308628970 | buy@fortunachem.com | China | 2866 | 58 |
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