Malonamide
- CAS No.
- 108-13-4
- Chemical Name:
- Malonamide
- Synonyms
- PROPANEDIAMIDE;MALONDIAMIDE;NSC 2134;MALONAMIDE;MALONODIAMIDE;Malonamide>AURORA KA-4099;malonicdiamide;Malonyldiamide;Malonamide 98%
- CBNumber:
- CB2418973
- Molecular Formula:
- C3H6N2O2
- Molecular Weight:
- 102.09
- MDL Number:
- MFCD00008034
- MOL File:
- 108-13-4.mol
- MSDS File:
- SDS
| Melting point | 172-175 °C (lit.) |
|---|---|
| Boiling point | 191.38°C (rough estimate) |
| Density | 1.3516 (rough estimate) |
| refractive index | 1.5110 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Soluble in HCl. |
| form | powder to crystal |
| pka | 7.00±0.70(Predicted) |
| color | White to Almost white |
| Water Solubility | 180 g/L (20 ºC) |
| BRN | 1751401 |
| InChI | InChI=1S/C3H6N2O2/c4-2(6)1-3(5)7/h1H2,(H2,4,6)(H2,5,7) |
| InChIKey | WRIRWRKPLXCTFD-UHFFFAOYSA-N |
| SMILES | C(N)(=O)CC(N)=O |
| CAS DataBase Reference | 108-13-4(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | QVQ8CNG255 |
| NIST Chemistry Reference | Propanediamide(108-13-4) |
| EPA Substance Registry System | Propanediamide (108-13-4) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H332-H335 | |||||||||
| Precautionary statements | P261-P280-P305+P351+P338 | |||||||||
| Safety Statements | 22-24/25 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | ON9125000 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29241900 | |||||||||
| NFPA 704 |
|
Malonamide price More Price(27)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 129593 | Malonamide 97% | 108-13-4 | 100g | $56.58 | 2024-03-01 | Buy |
| TCI Chemical | M0027 | Malonamide >98.0%(N) | 108-13-4 | 25g | $26 | 2024-03-01 | Buy |
| TCI Chemical | M0027 | Malonamide >98.0%(N) | 108-13-4 | 500g | $199 | 2024-03-01 | Buy |
| Alfa Aesar | A17939 | Malonamide, 98% | 108-13-4 | 100g | $65.65 | 2024-03-01 | Buy |
| Alfa Aesar | A17939 | Malonamide, 98% | 108-13-4 | 500g | $204.65 | 2024-03-01 | Buy |
Malonamide Chemical Properties,Uses,Production
Description
Malonamide is a dicarboxylic acid diamide that is malonic acid in which both carboxy groups have been replaced by carbamoyl groups. It is functionally related to a malonic acid.
Chemical Properties
White crystalline powder
Uses
Malonamide is a reagent for fluorimetric determination of reducing carbohydrates. The malonamide-based ionic liquid extractant was used in the extraction of europium(iii) and other trivalent rare earth elements from nitric acid medium.
Uses
The malonamide-based ionic liquid extractant was used in the extraction of europium(iii) and other trivalent rare-earth ions from nitric acid medium.
Uses
Malonamide is used in the synthesis of malonamic acid, malonamate and malonamide derivative of some heterocyclic compounds with antiinflammatory activity.
Definition
ChEBI: Malonamide is a dicarboxylic acid diamide that is malonic acid in which both carboxy groups have been replaced by carbamoyl groups. It is functionally related to a malonic acid.
General Description
The malonamide derivatives are obtained by the one-pot, five-component condensation reaction of isocyanide, Meldrum′s acid, arylidene malononitrile, and two amine molecules in CH2Cl2.
Hazard
Mildly toxic by ingestion.
Synthesis
The synthesis of Malonamide is as follows:
A typical reaction was carried out in a 10 mL flask. Benzonitrile (2 mmol), CuII-4 ? (0.2 g), acetaldoxime (6 mmol) and MeOH (4 mL) were stirred at 65 °C for 4 h. The solid was filtered, washed with MeOH and the filtrate evaporated. The residue was subjected to GC-MS analysis and NMR spectroscopy. The filtered catalyst can be recycled after drying at about 150 °C for 1 h.
Purification Methods
Crystallise the amide from water. [Beilstein 2 IV 1887.]
Malonamide Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanjing Triumpharm Co.,Ltd | +86-02586182925 +86-15105172550 | info@triumpharm.com | China | 129 | 58 |
| Nanjing Bicbiotechnology Co., Ltd | +86-2552131256 +86-18251840740 | sales@bicbiotech.com | China | 5994 | 58 |
| Hebei Weibang Biotechnology Co., Ltd | +8615531157085 | abby@weibangbio.com | China | 8810 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12839 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5892 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
| SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 | sales@sdzschem.com | China | 2930 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
View Lastest Price from Malonamide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-11 | Malonamide
108-13-4
|
US $10.00 / kg | 1kg | 99% | 10 mt | Hebei Weibang Biotechnology Co., Ltd | |
 |
2024-10-11 | Malonamide
108-13-4
|
US $9.00 / KG | 1KG | 99.8% | 100tons | Hebei Chuanghai Biotechnology Co,.LTD | |
 |
2023-08-26 | Malonamide
108-13-4
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd |
-
- Malonamide
108-13-4
- US $10.00 / kg
- 99%
- Hebei Weibang Biotechnology Co., Ltd
-
- Malonamide
108-13-4
- US $9.00 / KG
- 99.8%
- Hebei Chuanghai Biotechnology Co,.LTD
-
- Malonamide
108-13-4
- US $0.00 / KG
- 99%
- Hebei Mojin Biotechnology Co., Ltd