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(R)-(+)-4-HYDROXY-2-PYRROLIDINONE

(R)-(+)-4-HYDROXY-2-PYRROLIDINONE structure

CAS No.: 22677-21-0

Chemical Name:: (R)-(+)-4-HYDROXY-2-PYRROLIDINONE

Synonyms: RHPD;In1122 Impurity 78;Oxiracetam Impurity P;(R)-4-hydoroxyoyrolidone;4-hydroxy-R-2-pyrrolidine;(R)-4-HYDROXY-2-PYRROLIDONE;(r)-β-hydroxy-γ-butyrolactam;（R)+4-hydroxy-2-prrolidinone;(R)-4-hydroxy-2-pyrrolidione;(4R)-4-hydroxy-2-pyrrolidone

CBNumber:: CB2438434

Molecular Formula:: C4H7NO2

Molecular Weight:: 101.1

MDL Number:: MFCD00273364

MOL File:: 22677-21-0.mol

MSDS File:: SDS

Last updated:2023-04-23 13:52:06

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(R)-(+)-4-HYDROXY-2-PYRROLIDINONE Properties

Melting point	156-160 °C
Boiling point	363.6±35.0 °C(Predicted)
Density	1.292±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
solubility	DMSO (Sparingly), Methanol (Slightly), Water (Sparingly)
pka	13.62±0.20(Predicted)
form	Powder
color	White to pale yellow
optical activity	[α]23/D +43°, c = 1 in ethanol
Water Solubility	Slightly soluble in water.
BRN	1524193
InChIKey	IOGISYQVOGVIEU-GSVOUGTGSA-N
CAS DataBase Reference	22677-21-0(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

Hazard Codes

Risk Statements

36/37/38-38-37-36

Safety Statements

WGK Germany

HS Code

29339900

NFPA 704

	1
2		0

(R)-(+)-4-HYDROXY-2-PYRROLIDINONE price More Price(37)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	479160	(R)-(+)-4-Hydroxy-2-pyrrolidinone 97%	22677-21-0	1g	$111	2024-03-01	Buy
Sigma-Aldrich	479160	(R)-(+)-4-Hydroxy-2-pyrrolidinone 97%	22677-21-0	5g	$417	2023-06-20	Buy
Alfa Aesar	H66006	(R)-(+)-4-Hydroxy-2-pyrrolidinone, 97+%	22677-21-0	250mg	$42.7	2023-06-20	Buy
Alfa Aesar	H66006	(R)-(+)-4-Hydroxy-2-pyrrolidinone, 97+%	22677-21-0	1g	$113	2021-12-16	Buy
TRC	H953070	(R)-(+)-4-Hydroxy-2-pyrrolidinone	22677-21-0	1g	$1110	2021-12-16	Buy

Product number	Packaging	Price	Buy
479160	1g	$111	Buy
479160	5g	$417	Buy
H66006	250mg	$42.7	Buy
H66006	1g	$113	Buy
H953070	1g	$1110	Buy

(R)-(+)-4-HYDROXY-2-PYRROLIDINONE Chemical Properties,Uses,Production

Chemical Properties

white to light yellow crystal powde

Uses

The (R)-enantiomer intermediate in the preparation of Oxiracetam

Uses

(R)-(+)-4-Hydroxy-2-pyrrolidinone intermediate in the preparation of Oxiracetam. Also used as enantiomeric intermediate for the asymmetric single isomeric drugs including antitumor, anesthetic, antipasmodic, anti-inflammatory or anti-HIV activity products.

(R)-(+)-4-HYDROXY-2-PYRROLIDINONE synthesis

Synthesis of (R)-(+)-4-HYDROXY-2-PYRROLIDINONE from Butanoic acid, 4-amino-3-hydroxy-, ethyl ester, (3R)-

(R)-(+)-4-HYDROXY-2-PYRROLIDINONE Preparation Products And Raw materials

Raw materials

Butanoic acid, 4-amino-3-hydroxy-, ethyl ester, (3R)- 2-Pyrrolidinone, 1-[(1S)-1-phenylethyl]-4-(phenylmethoxy)-, (4R)-

Preparation Products

(R)-(+)-4-HYDROXY-2-PYRROLIDINONE Suppliers

Global( 180)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29791	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	18777	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29881	58
Klong Industrial Co., Ltd	0086-519-68231162	info@klongchem.com	CHINA	131	58
Changzhou Ansciep Chemical Co., Ltd.	+86 519 86305871	sales@ansciepchem.com	CHINA	4241	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	17322	58
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	sales@chemdad.com	China	39894	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49374	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
career henan chemical co	58
Klong Industrial Co., Ltd	58
Changzhou Ansciep Chemical Co., Ltd.	58
Accela ChemBio Inc.	58
Chongqing Chemdad Co., Ltd	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58

View Lastest Price from (R)-(+)-4-HYDROXY-2-PYRROLIDINONE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2019-07-06	(R)-(+)-4-HYDROXY-2-PYRROLIDINONE 22677-21-0	US $1.00 / kg	1kg	95%-99%	as request	Career Henan Chemical Co

(R)-(+)-4-HYDROXY-2-PYRROLIDINONE
22677-21-0
US $1.00 / kg
95%-99%
Career Henan Chemical Co

22677-21-0((R)-(+)-4-HYDROXY-2-PYRROLIDINONE)Related Search:

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(R)-(+)-4-HYDROXY-2-PYRROLIDINONE (R)-4-HYDROXY-2-PYRROLIDINONE (R)-4-HYDROXY-2-PYRROLIDONE (R)-BETA-HYDROXY-GAMMA-BUTYROLACTAM RHPD 2-PYRROLIDINONE, 4-HYDROXY-, (R) 4-hydroxy-R-2-pyrrolidine (r)-(+)-β-hydroxy-γ-butyrolactam (r)-β-hydroxy-γ-butyrolactam 2-Pyrrolidinone, 4-hydroxy-, (4R)- (R)-4-hydoroxyoyrolidone （R)+4-hydroxy-2-prrolidinone (R)-4-Hydroxy-pyrrolidin-2-one (4R)-4-Hydroxypyrrolidine-2-one (R)-4β-Hydroxypyrrolidine-2-one [4R,(-)]-4-Hydroxypyrrolidin-2-one (R)-4-hydroxy-2-pyrrolidione (4R)-4-hydroxy-2-pyrrolidone (4R)-4-Hydroxy-2-pyrrolidinone In1122 Impurity 78 Oxiracetam Impurity P (R)-(+)-4-Hydroxy-2-pyrrolidinone, 97%, 22677-21-0 Chiral Building Blocks Asymmetric Synthesis Heterocyclic Building Blocks Pyrrolidines Pyrrole&Pyrrolidine&Pyrroline Amines Chiral Reagents Heterocycles Intermediates & Fine Chemicals Pharmaceuticals Drug Intermediates