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SUCCINYL COENZYME A SODIUM SALT

CAS No.
108347-97-3
Chemical Name:
SUCCINYL COENZYME A SODIUM SALT
Synonyms
Succinyl CoA, Li-salt;Succinyl-CoA-sodium-salt;succinyl coenzyme A sodium;SUCCINYL COENZYME A SODIUM SALT;Succinyl coenzyme A sodium salt >=85%;coenzyme A succinyl derivative, trisodium salt;Coenzyme A,S-(hydrogen butanedioate),sodium salt;Coenzyme A, S-(hydrogenbutanedioate), sodium salt (9CI)
CBNumber:
CB2444570
Molecular Formula:
C25H41N7NaO19P3S
Molecular Weight:
891.6
MDL Number:
MFCD00057770
MOL File:
108347-97-3.mol
MSDS File:
SDS
Last updated:2024-11-12 15:22:20

SUCCINYL COENZYME A SODIUM SALT Properties

storage temp. -20°C
solubility PBS (pH 7.2): 10 mg/ml
form A crystalline solid
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  22-26-36
WGK Germany  3
NFPA 704
0
2 0

SUCCINYL COENZYME A SODIUM SALT price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S1129 Succinyl coenzyme A sodium salt ≥85% 108347-97-3 5mg $258 2024-03-01 Buy
Sigma-Aldrich S1129 Succinyl coenzyme A sodium salt ≥85% 108347-97-3 25mg $973 2024-03-01 Buy
Cayman Chemical 23297 Succinyl-Coenzyme A (sodium salt) ≥95% 108347-97-3 1mg $56 2024-03-01 Buy
Cayman Chemical 23297 Succinyl-Coenzyme A (sodium salt) ≥95% 108347-97-3 5mg $201 2024-03-01 Buy
Cayman Chemical 23297 Succinyl-Coenzyme A (sodium salt) ≥95% 108347-97-3 10mg $376 2024-03-01 Buy
Product number Packaging Price Buy
S1129 5mg $258 Buy
S1129 25mg $973 Buy
23297 1mg $56 Buy
23297 5mg $201 Buy
23297 10mg $376 Buy

SUCCINYL COENZYME A SODIUM SALT Chemical Properties,Uses,Production

Description

Succinyl-coenzyme A (succinyl-CoA) is an intermediate in the citric acid cycle. It is converted to succinate, which is a metabolic intermediate with various biological activities. Succinyl-CoA is required, with glycine, to form δ-aminolevulinic acid in the first step of porphyrin and heme synthesis. Succinyl-CoA deficiency, caused by vitamin B12 deficiency can disrupt heme and energy production, leading to neuromotor dysfunction.

Uses

Succinyl coenzyme A sodium salt has been used:

  • for the nonenzymatic succinylation of lysine in vitro,
  • as a substrate for adipic acid biosynthesis in recombinant E. coli
  • in isocitrate dehydrogenase (ICDH)?treatment for the succinylation of proteins
  • as a substrate to study the specificity and kinetics of enzymes such as acetate:succinate CoA-transferase and 5-aminolevulinate synthase (ALA synthase)

Biochem/physiol Actions

Succinyl CoA is an intermediate in the citric acid cycle. It is formed by α-ketoglutarate dehydrogenase by the decarboxylation of α-ketoglutarate. Succinyl CoA is also formed from propionyl CoA during the β-oxidation of odd-chain fatty acids. Succinyl CoA serves as a precursor in heme synthesis. It is also required for the oxidation of ketone bodies.

Purification Methods

If it should be purified further, then it should be dissolved in H2O (0.05g/mL) adjusted to pH 1 with 2M H2SO4 and extracted several times with Et2O. Excess Et2O is removed from the aqueous layer by bubbling N2 through it and is stored frozen at pH 1. When required, the pH should be adjusted to 7 with dilute NaOH and used within 2 weeks (samples should be frozen). Succinyl coenzyme A is estimated by the hydroxamic acid method [Hersch & Jencks J Biol Chem 242 3468 1967]. It is more stable in acidic than in neutral aqueous solutions, but neutral solutions can be stored at –15o with negligible decomposition. [Jordan & Laghai-Newton Methods Enzymol 123 435 1986, Beilstein 26 III/IV 3666.]

SUCCINYL COENZYME A SODIUM SALT Preparation Products And Raw materials

Raw materials

Preparation Products

SUCCINYL COENZYME A SODIUM SALT Suppliers

Global( 35)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32161 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418684 +8618949823763 sales@tnjchem.com China 25356 58
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 57505 58
Shanghai Yingxin laboratory equipment Co., Ltd 021-021-59178156 15300768757 359382369@qq.com China 10674 58
Chengdu HuaXia Chemical Reagent Co. Ltd 400-1166-196 13458535857 cdhxsj@163.com China 13350 58
Shanghai Macklin Biochemical Co.,Ltd. 15221275939 15221275939 shenlinxing@macklin.cn China 16166 55
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51456 80
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9806 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6777 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11218 58

View Lastest Price from SUCCINYL COENZYME A SODIUM SALT manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Succinyl-Coenzyme A sodium salt pictures 2024-11-12 Succinyl-Coenzyme A sodium salt
108347-97-3
US $140.00 / mg 10g TargetMol Chemicals Inc.
SUCCINYL COENZYME A SODIUM SALT succinyl coenzyme A sodium coenzyme A succinyl derivative, trisodium salt Succinyl CoA, Li-salt Succinyl coenzyme A sodium salt >=85% Coenzyme A,S-(hydrogen butanedioate),sodium salt Coenzyme A, S-(hydrogenbutanedioate), sodium salt (9CI) Succinyl-CoA-sodium-salt 108347-97-3 C25H38N7Na2O19P3S Metabolic Libraries Lipid Library Metabolomics BioChemical Aminolevulinate synthase, 5-Saturated fatty acids and derivatives Cofactors Enzymes, Inhibitors, and Substrates Esters Fatty acyl CoAsMetabolic Pathways Lipid Library LipidMetabolomics Metabolic Libraries Metabolites and Cofactors on the Metabolic Pathways Chart Substrates by Enzyme Acyl Transfer ReagentsEnzyme Substrates