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(8,9-DiHETE

CAS No.
867350-87-6
Chemical Name:
(8,9-DiHETE
Synonyms
(8,9-DiHETE;8,9-dihydroxy-5(Z),11(Z),14(Z),17(Z)-eicosatetraenoic acid
CBNumber:
CB24665672
Molecular Formula:
C20H32O4
Molecular Weight:
336.46568
MDL Number:
MOL File:
867350-87-6.mol
Last updated:2023-06-08 09:03:09

(8,9-DiHETE Properties

solubility DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 0.5 mg/ml

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H319
Precautionary statements  P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501
NFPA 704
3
2 0

(8,9-DiHETE price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 10473 (±)8,9-DiHETE ≥98% 867350-87-6 25μg $105 2024-03-01 Buy
Cayman Chemical 10473 (±)8,9-DiHETE ≥98% 867350-87-6 50μg $195 2024-03-01 Buy
Cayman Chemical 10473 (±)8,9-DiHETE ≥98% 867350-87-6 100μg $369 2024-03-01 Buy
Product number Packaging Price Buy
10473 25μg $105 Buy
10473 50μg $195 Buy
10473 100μg $369 Buy

(8,9-DiHETE Chemical Properties,Uses,Production

Description

(±)8(9)-DiHETE is a major metabolite of the 20:5 ω-3 fatty acid eicosapentaenoic acid (EPA; ).1 It is produced in rat liver microsomes, but not renal microsomes, by the generation of the unstable intermediate 8,9-epoxy eicosatetraenoic acid from EPA by cytochrome P450 monooxygenases.1 Dietary EPA supplementation in humans results in substantial urinary excretion of vicinal diols, including 8,9, 11,12, and 14,15 forms.2

Definition

ChEBI: 8,9-DiHETE is a hydroxy fatty acid and a polyunsaturated fatty acid.

References

1. VanRollins, M., Frade, P.D., and Carretero, O.A. Oxidation of 5,8,11,14,17-eicosapentaenoic acid by hepatic and renal microsomes Biochim. Biophys. Acta 996,133-149(1988).
2. Knapp, H.R., Miller, A.J., and Lawson, J.A. Urinary excretion of diols derived from eicosapentaenoic acid during N-3 fatty acid ingestion Prostaglandins 42,47-53(1991).

(8,9-DiHETE Preparation Products And Raw materials

Raw materials

Preparation Products

(8,9-DiHETE Suppliers

Global( 11)Suppliers
Supplier Tel Email Country ProdList Advantage
Alfa Chemistry
Info@alfa-chemistry.com United States 24072 58
Yichang Zhongyitai Trading Co., Ltd. 0717-6449896 13886658719 root@zhongyitai.com China 1977 58
Alfa Chemistry 1-516-6625404 support@alfa-chemistry.com United States 9171 60
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6777 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11217 58
amyjetsci 027-59626688 18771149750 sales@amyjet.com China 3003 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24648 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11974 58
SHANGHAI ZZBIO CO., LTD. 15102117276 19921389125 tech@zzbioco.com China 12065 58
(8,9-DiHETE 8,9-dihydroxy-5(Z),11(Z),14(Z),17(Z)-eicosatetraenoic acid 867350-87-6