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CYM-5478

CAS No.
870762-83-7
Chemical Name:
CYM-5478
Synonyms
CYM-5478;1-[2-(1-benzyl-2,5-dimethyl-1H-pyrrol-3-yl)-2-oxoethyl]-5-(trifluoromethyl)-1,2-dihydropyridin-2-one;1-[2-[2,5-dimethyl-1-(phenylmethyl)-1H-pyrrol-3-yl]-2-oxoethyl]-5-(trifluoromethyl)-2(1H)-pyridinone;2(1H)-Pyridinone, 1-[2-[2,5-dimethyl-1-(phenylmethyl)-1H-pyrrol-3-yl]-2-oxoethyl]-5-(trifluoromethyl)-
CBNumber:
CB24718602
Molecular Formula:
C21H19F3N2O2
Molecular Weight:
388.38
MDL Number:
MFCD07342414
MOL File:
870762-83-7.mol
Last updated:2024-10-23 13:36:13

CYM-5478 Properties

Boiling point 527.1±50.0 °C(Predicted)
Density 1.23±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO: soluble
form A crystalline solid
pka -2.22±0.70(Predicted)
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H302-H335-H319
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362-P264-P270-P301+P312-P330-P501

CYM-5478 price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 29024 CYM 5478 870762-83-7 1mg $93 2024-03-01 Buy
Cayman Chemical 29024 CYM 5478 870762-83-7 5mg $412 2024-03-01 Buy
AK Scientific 8735CQ 1-[2-(1-Benzyl-2,5-dimethylpyrrol-3-yl)-2-oxoethyl]-5-(trifluoromethyl)pyridin-2-one 870762-83-7 1mg $201 2021-12-16 Buy
Product number Packaging Price Buy
29024 1mg $93 Buy
29024 5mg $412 Buy
8735CQ 1mg $201 Buy

CYM-5478 Chemical Properties,Uses,Production

Description

CYM 5478 is a sphingosine-1-phosphate receptor 2 (S1P2) agonist (EC50 = 0.78 μM in a reporter assay). It is selective for S1P2 over S1P1 and S1P3-5 in a TGFα-shedding assay (EC50s = 119, 1,690, 1,950, >10,000, and >10,000 nM, respectively). CYM 5478 (0.1-10 μM) reduces serum starvation-induced decreases in C6 rat glioma cell viability. It also reduces accumulation of reactive oxygen species (ROS) and apoptosis induced by cisplatin in C6 cells when used at a concentration of 10 μM.

CYM-5478 Preparation Products And Raw materials

Raw materials

Preparation Products

CYM-5478 Suppliers

Global( 14)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32063 58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd
+86-18341751992 +86-15382112998 757984502@qq.com China 892 58
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696,15000506266 15000506266 China 4456 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9806 58
ShangHai Biochempartner Co.,Ltd 177-54423994 17754423994 2853530910@QQ.com China 8014 62
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6777 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11217 58
Changzhou Furuisi Biotechnology Co., Ltd 0519-85524369 3477467573@qq.com China 8617 58
Jinan Jiuli Biotechnology Co. , Ltd. 15865264761 486064515@qq.com China 3547 58
Shanghai Universal Biotech Co.,Ltd 13774214275 gaojun@univ-bio.com China 24990 58

View Lastest Price from CYM-5478 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
CYM-5478 pictures 2024-10-24 CYM-5478
870762-83-7
US $233.00-987.00 / mg 10g TargetMol Chemicals Inc.
  • CYM-5478 pictures
  • CYM-5478
    870762-83-7
  • US $233.00-987.00 / mg
  • TargetMol Chemicals Inc.
CYM-5478 2(1H)-Pyridinone, 1-[2-[2,5-dimethyl-1-(phenylmethyl)-1H-pyrrol-3-yl]-2-oxoethyl]-5-(trifluoromethyl)- 1-[2-[2,5-dimethyl-1-(phenylmethyl)-1H-pyrrol-3-yl]-2-oxoethyl]-5-(trifluoromethyl)-2(1H)-pyridinone 1-[2-(1-benzyl-2,5-dimethyl-1H-pyrrol-3-yl)-2-oxoethyl]-5-(trifluoromethyl)-1,2-dihydropyridin-2-one 870762-83-7