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JAK3 covalent inhibitor-1
- CAS No.
- 2300106-50-5
- Chemical Name:
- JAK3 covalent inhibitor-1
- Synonyms
- JAK3 COVALENT INHIBITOR-1;JAK3 covalent inhibitor1,JAK3 covalent inhibitor 1,JAK-3 covalent inhibitor-1;Benzenesulfonamide, N-[(1R,3S)-3-(cyanoamino)-2,3-dihydro-5-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-inden-1-yl]-3-fluoro-
- CBNumber:
- CB25540374
- Molecular Formula:
- C22H17FN6O2S
- Molecular Weight:
- 448.47
- MDL Number:
- MFCD32067927
- MOL File:
- 2300106-50-5.mol
Last updated:2023-05-21 10:59:17
JAK3 covalent inhibitor-1 Chemical Properties,Uses,Production
Description
JAK3 covalent inhibitor-1 is a potent and selective janus kinase 3 (JAK3) covalent inhibitor with an IC50 of 11 nM and shows 246-fold selectivity vs other JAKs[1]. JAK3|11 nM (IC50)
References
[1]. Casimiro-Garcia A, et al. Identification of Cyanamide-Based Janus Kinase 3 (JAK3) Covalent Inhibitors. J Med Chem. 2018 Dec 13;61(23):10665-10699.
JAK3 covalent inhibitor-1 Preparation Products And Raw materials
Raw materials
Preparation Products
JAK3 covalent inhibitor-1 Suppliers
Global( 4)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Chengdu Peter-like Biotechnology Co., Ltd. | 028-81700200 18108052721 | 2850505130@qq.com | China | 5178 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24647 | 58 |
| Nantong Hanfang Biotechnology Co. , Ltd. | 18616537568 | hanfangpharma@126.com | China | 30968 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| Chengdu Peter-like Biotechnology Co., Ltd. | 58 |
| TargetMol Chemicals Inc. | 58 |
| Nantong Hanfang Biotechnology Co. , Ltd. | 58 |
JAK3 COVALENT INHIBITOR-1
JAK3 covalent inhibitor1,JAK3 covalent inhibitor 1,JAK-3 covalent inhibitor-1
Benzenesulfonamide, N-[(1R,3S)-3-(cyanoamino)-2,3-dihydro-5-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-inden-1-yl]-3-fluoro-
2300106-50-5